Product image of Iodeto De Sódio (131i) Ge Healthcare (Sodium Iodide (131i)) supplied by GNH India

Iodeto De Sódio (131i) Ge Healthcare

Active Ingredient:
Sodium Iodide (131i)
Origin:
EU

Iodeto De Sódio (131i) Ge Healthcare (Sodium Iodide (131i))

Sodium Iodide (131I), the active ingredient in Iodeto De Sódio (131i) Ge Healthcare, is a diagnostic radiopharmaceutical presented as an oral preparation for thyroid imaging use. It enables visualization of thyroid function and structure in patients undergoing evaluation for thyroid disorders.

GNH India supplies Iodeto De Sódio (131i) Ge Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ge Healthcare Buchler Gmbh & Co. Kg

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Indications & Clinical Uses

Iodeto De Sódio (131i) is employed in diagnostic procedures that assess thyroid function and anatomy.

  • Thyroid scintigraphy: visualizes functional thyroid tissue to assess hormone production patterns.
  • Hyperthyroidism evaluation: distinguishes toxic nodular disease from Graves' disease by measuring iodine uptake.
  • Thyroid cancer staging: detects residual or metastatic thyroid tissue after thyroidectomy.
  • Ectopic thyroid tissue identification: locates thyroid tissue outside the neck for surgical planning.

How It Works

  • Sodium Iodide (131I) is a radioactive isotope that mimics natural iodine. After oral ingestion, it is selectively taken up by thyroid follicular cells via the sodium‑iodide symporter. The emitted gamma radiation allows external imaging devices to generate high‑resolution pictures of thyroid tissue distribution, facilitating functional and anatomical assessment.

Side Effects

Adverse reactions may occur following administration of Iodeto De Sódio (131i).

Common Side Effects

  • Nausea: mild to moderate feeling of stomach upset.
  • Metallic taste: transient alteration of taste perception.
  • Headache: mild to moderate headache lasting a few hours.
  • Dry mouth: temporary reduction in salivary flow.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, or swelling requiring medical attention.
  • Radiation thyroiditis: inflammation of the thyroid gland causing pain.
  • Severe hypothyroidism: marked reduction in thyroid hormone production.
  • Bone marrow suppression: rare decrease in blood cell counts.

Precautions & Warnings

Before using Iodeto De Sódio (131i), consider the following safety measures.

  • Pregnancy: avoid unless the diagnostic benefit outweighs potential fetal radiation risk.
  • Breastfeeding: discontinue nursing or choose an alternative, as iodine can be secreted in milk.
  • Baseline thyroid function: assess thyroid hormone levels prior to administration.
  • Radiation safety: limit close contact with pregnant persons and young children for 24 hours after dosing.
  • Renal impairment: evaluate kidney function, as excretion may be delayed.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture and light.

Avoid Interactions

Iodeto De Sódio (131i) may interact with other agents that affect iodine metabolism or radiation exposure.

Major Interactions (Avoid)

  • Concurrent radioactive iodine therapies: may lead to cumulative radiation dose.
  • Iodinated contrast media: can block thyroid uptake of the radiopharmaceutical.
  • Antithyroid drugs (e.g., methimazole, propylthiouracil): reduce iodine uptake and compromise imaging quality.

Moderate Interactions (Monitor Closely)

  • Thyroid hormone replacement (levothyroxine): may alter baseline thyroid activity.
  • Diuretics: can affect renal clearance of iodine.
  • Iodine‑rich supplements (e.g., kelp, seaweed): may compete with tracer uptake.

Frequently Asked Questions

Iodeto De Sódio (131i) is a diagnostic radiopharmaceutical used to image the thyroid gland. It helps clinicians assess thyroid function, detect abnormal tissue such as nodules or cancer, and evaluate conditions like hyperthyroidism by visualizing how the gland takes up iodine.

Sodium Iodide (131I) behaves like natural iodine and is actively transported into thyroid cells. The radioactive iodine emits gamma photons that can be captured by a gamma camera, producing images that reflect the distribution and activity of thyroid tissue throughout the body.

The prescribed dose of Iodeto De Sódio (131i) is determined by the treating physician based on the specific diagnostic indication, patient weight, thyroid status, and local regulatory guidelines. Exact dosing information is not provided in product literature and must be individualized.

Data on the safety of radioactive iodine in pregnancy and lactation are limited. Because the tracer delivers radiation to the fetus or infant, it is generally avoided unless the diagnostic benefit is essential and no safer alternative exists. Consultation with a specialist is required.

To request Iodeto De Sódio (131i), submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The most common alternative is Technetium‑99m pertechnetate, which also images thyroid uptake but provides lower radiation dose and faster imaging. Sodium Iodide (131I) offers both diagnostic imaging and therapeutic potential, delivering higher-energy gamma photons that yield superior image resolution for certain clinical scenarios.

Store the product at ambient temperature below 25 °C, in its original sealed container, protected from moisture and direct light. Keep the package closed when not in use and handle it according to local radiation safety regulations to avoid contamination.

Iodeto De Sódio (131i) is administered orally. The patient swallows the prescribed dose with a glass of water, typically on an empty stomach, and follows any fasting instructions provided by the nuclear medicine team before imaging.

Serious risks include allergic reactions, radiation‑induced thyroiditis, severe hypothyroidism, and, rarely, bone‑marrow suppression. Patients should be monitored for signs of these events, and any unexpected symptoms should be reported to a healthcare professional promptly.

Contraindications include known hypersensitivity to iodine or radioactive iodine compounds, pregnancy unless absolutely necessary, active breastfeeding, and patients with uncontrolled thyroid disorders where imaging could alter management without benefit. Clinicians should evaluate each case individually.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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