Jodek Sodu Na 131i Narodowe Centrum Badań Jądrowych (Sodium Iodide (131i))

• Jodek Sodu Na 131i Narodowe Centrum Badań Jądrowych is used in diagnostic procedures that target the thyroid gland and related pathologies.
• Thyroid scintigraphy: provides functional imaging of thyroid tissue distribution for diagnostic evaluation.
• Thyroid cancer metastasis detection: identifies iodine‑avid metastatic lesions to guide staging.
• Thyroid function assessment: evaluates gland activity and hormone synthesis capacity in clinical investigations.

• Sodium Iodide (I-131) is selectively taken up by thyroid follicular cells via the sodium‑iodide symporter. Once inside the gland, the radioactive iodine emits beta particles that cause localized radiation and gamma photons that are captured by imaging equipment, allowing visualization of thyroid tissue and functional assessment without significantly affecting surrounding structures.

Adverse reactions may occur following intravenous administration of I‑131 diagnostic solutions.

Common Side Effects

• Nausea or mild vomiting
• Transient headache or dizziness
• Temporary alteration of taste sensation
• Mild injection‑site pain or erythema
• Low‑grade fever or chills

Serious or Rare Side Effects

• Allergic reaction including urticaria or anaphylaxis
• Radiation thyroiditis causing painful swelling
• Hematologic changes such as leukopenia
• Pulmonary radiation pneumonitis (very rare)
• Severe radiation‑induced organ injury in high‑dose exposures

• Prior to use, clinicians should evaluate patient‑specific factors and follow radiation safety guidelines.
• Pregnancy: avoid unless essential, as fetal thyroid may be exposed.
• Breastfeeding: discontinue nursing or consider alternative imaging.
• Baseline thyroid function: assess before administration to interpret results accurately.
• Radiation safety: implement shielding and limit exposure for staff and nearby patients.
• Concurrent iodine‑containing drugs: review and possibly withhold to prevent uptake interference.
• Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

I‑131 diagnostic agents can interact with substances that alter iodine handling or thyroid activity.

Major Interactions (Avoid)

• Therapeutic doses of stable iodine (e.g., potassium iodide) – blocks thyroid uptake.
• High‑dose thyroid hormone suppressive therapy – may reduce diagnostic accuracy.

Moderate Interactions (Monitor Closely)

• Amiodarone – high iodine content, may affect uptake.
• Iodinated contrast agents – schedule imaging to avoid interference.
• Antithyroid medications – may diminish tracer accumulation.