Product image of Somatuline AutoGel 120mg-SW (Lanreotide ) 120mg Injection supplied by GNH India

Somatuline AutoGel 120mg-SW

Active Ingredient:
Lanreotide
Form:
Injection
Brand:
Somatuline AutoGel 120mg-SW
Origin:
Switzerland

Somatuline AutoGel 120mg-SW (Lanreotide Injection) 120mg

Lanreotide, the active ingredient in Somatuline AutoGel 120mg-SW, is a somatostatin analog presented as a 120mg injection for subcutaneous use. It is used to treat acromegaly and symptoms associated with neuroendocrine tumors.

GNH India supplies Somatuline AutoGel 120mg-SW as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

120mg

Pack Size

1s

Storage

2-8°

Manufacturer / TM Owner

IPSEN PHARMA SCHWEIZ Switzerland

1
Pack/s
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Indications & Clinical Uses

Somatuline AutoGel 120mg-SW is a somatostatin analog used to manage conditions related to hormone secretion and neuroendocrine tumors.

  • Acromegaly: Reduces growth hormone and IGF-1 levels to manage symptoms of acromegaly.
  • Neuroendocrine tumors: Controls symptoms and slows disease progression in gastroenteropancreatic neuroendocrine tumors (GEP-NETs).
  • Carcinoid syndrome: Alleviates symptoms such as diarrhea and flushing associated with carcinoid tumors.

How It Works

  • Lanreotide is a synthetic analogue of somatostatin that binds to somatostatin receptors, primarily SSTR2 and SSTR5. By binding to these receptors, it inhibits the secretion of growth hormone, insulin-like growth factor-1 (IGF-1), and other hormones, thereby reducing their effects on the body.

Side Effects

Somatuline AutoGel 120mg-SW may cause several side effects, ranging from common to serious.

Common Side Effects

  • Gastrointestinal issues: Diarrhea, abdominal pain, nausea.
  • Injection site reactions: Pain, swelling, or redness at the injection site.
  • Gallbladder issues: Gallstones, often asymptomatic.
  • Fatigue: General tiredness or weakness.
  • Hypoglycemia: Low blood sugar levels.
  • Constipation: Difficulty in bowel movements.

Serious or Rare Side Effects

  • Allergic reactions: Angioedema, anaphylaxis.
  • Gallbladder complications: Severe gallstone-related issues.
  • Cardiovascular issues: Bradycardia, changes in heart rate.
  • Hypothyroidism: Reduced thyroid function.
  • Vitamin B12 deficiency: Due to reduced absorption.

Precautions & Warnings

Somatuline AutoGel 120mg-SW should be used with caution and under medical supervision.

  • Monitoring: Regular monitoring of gallbladder function and blood glucose levels is recommended.
  • Pregnancy: Use during pregnancy should be carefully considered due to potential risks.
  • Breastfeeding: Consult a healthcare provider before use while breastfeeding.
  • Pre-existing conditions: Inform your doctor about any pre-existing conditions, especially gallbladder or heart issues.
  • Drug interactions: Inform your doctor about all medications you are taking.
  • Storage: Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Somatuline AutoGel 120mg-SW may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects.

Major Interactions (Avoid)

  • Cyclosporine: May increase cyclosporine levels, leading to toxicity.
  • Bromocriptine: May reduce the effectiveness of bromocriptine.
  • Insulin and oral hypoglycemic agents: May require dose adjustment due to changes in blood sugar levels.

Moderate Interactions (Monitor Closely)

  • Beta-blockers: May enhance the bradycardic effects.
  • Calcium channel blockers: May require monitoring for changes in blood pressure.
  • Immunosuppressants: May require dose adjustment due to potential interactions.

Frequently Asked Questions

Somatuline AutoGel 120mg-SW is used to treat acromegaly and symptoms associated with neuroendocrine tumors. It helps reduce growth hormone and IGF-1 levels, manage symptoms of carcinoid syndrome, and control the progression of gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

Lanreotide is a synthetic analogue of somatostatin that binds to somatostatin receptors, primarily SSTR2 and SSTR5. By binding to these receptors, it inhibits the secretion of growth hormone, insulin-like growth factor-1 (IGF-1), and other hormones, thereby reducing their effects on the body.

The usual dose of Somatuline AutoGel 120mg-SW is determined by a healthcare provider based on the patient's condition and response to treatment. The recommended starting dose for acromegaly or carcinoid syndrome is 60 mg to 120 mg injected every 28 days.

The safety of Somatuline AutoGel 120mg-SW during pregnancy has not been established. Use during pregnancy should be carefully considered and discussed with a healthcare provider, weighing the potential benefits and risks.

To order Somatuline AutoGel 120mg-SW from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then provide pricing, availability, shipping, and the necessary import paperwork.

Somatuline AutoGel 120mg-SW is a long-acting somatostatin analog that offers convenient dosing compared to other treatments like octreotide. It is effective in reducing growth hormone and IGF-1 levels, making it a suitable option for managing acromegaly and related conditions.

Somatuline AutoGel 120mg-SW should be stored at 2-8°C, refrigerated, and protected from light. It should not be frozen or shaken. After removal from the refrigerator, it can be kept at room temperature for up to 72 hours if not used immediately.

Somatuline AutoGel 120mg-SW is administered as a deep subcutaneous injection in the upper outer quadrant of the buttock or the upper outer thigh. The injection should be performed by a healthcare professional.

The most serious risks associated with Somatuline AutoGel 120mg-SW include allergic reactions such as angioedema and anaphylaxis, severe gallbladder complications, and significant changes in heart rate. Patients should be monitored closely for these potential adverse effects.

Patients with known hypersensitivity to lanreotide or any of the excipients in Somatuline AutoGel 120mg-SW should not use this medication. Additionally, patients with severe gallbladder disease or those who have experienced severe allergic reactions to similar medications should avoid using it.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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