Product image of Tenectelex 40mg (Tenecteplase ) 40mg Vials supplied by GNH India

Tenectelex 40mg

Active Ingredient:
Tenecteplase
Form:
Vials
Brand:
Tenectelex 40mg
Origin:
India

Tenectelex 40mg (Tenecteplase Vials) 40mg

Tenecteplase, the active ingredient in Tenectelex 40mg, is a thrombolytic presented as a 40mg vial for intravenous use. It is used to dissolve blood clots in the heart during acute myocardial infarction (STEMI).

GNH India supplies Tenectelex 40mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Strength

40mg

Pack Size

1s

Storage

2-8°

Manufacturer / TM Owner

Abbott Healthcare Pvt Ltd

1
Pack/s
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Indications & Clinical Uses

Tenectelex 40mg is a thrombolytic agent used to treat conditions involving blood clots.

  • Acute myocardial infarction (STEMI): Dissolves blood clots in the coronary arteries to restore blood flow and minimize heart damage.
  • Pulmonary embolism: Breaks down clots in the lungs to improve oxygenation and reduce strain on the heart.
  • Ischemic stroke: Helps dissolve clots in the brain to restore blood flow and reduce neurological damage.

How It Works

  • Tenecteplase is a recombinant tissue-type plasminogen activator that converts plasminogen to plasmin, leading to the degradation of fibrin clots. This action helps to restore blood flow in blocked vessels, particularly in the heart during a heart attack.

Side Effects

Tenectelex 40mg may cause several side effects, ranging from common to serious.

Common Side Effects

  • Bleeding at the injection site
  • Nosebleeds
  • Bruising
  • Blood in the urine
  • Gastrointestinal bleeding
  • Injection site reactions

Serious or Rare Side Effects

  • Severe bleeding
  • Stroke
  • Allergic reactions
  • Internal bleeding
  • Anaphylaxis

Precautions & Warnings

Tenectelex 40mg should be used with caution and under medical supervision.

  • Allergies: Inform your doctor if you are allergic to Tenecteplase or any other medicines.
  • Age and Weight: Use with caution in patients aged over 75 years and who weigh less than 60 kg.
  • Pregnancy and Breastfeeding: Inform your doctor if you are pregnant or breastfeeding.
  • Recent Surgery or Trauma: Inform your doctor if you have had recent major surgery or trauma.
  • Cardiovascular Conditions: Inform your doctor if you have a history of bleeding disorders or recent bleeding.
  • Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Tenectelex 40mg may interact with other medications, requiring careful monitoring.

Major Interactions (Avoid)

  • Blood thinners (e.g., ticlopidine, clopidogrel, heparin, vitamin K antagonists): Increased risk of bleeding.
  • Other thrombolytics: Increased risk of severe bleeding.

Moderate Interactions (Monitor Closely)

  • Antiplatelet drugs: Increased risk of bleeding.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Increased risk of gastrointestinal bleeding.
  • Anticoagulants: Increased risk of bleeding.

Frequently Asked Questions

Tenectelex 40mg is used to dissolve blood clots in the heart during acute myocardial infarction (STEMI). It helps to restore blood flow and minimize heart damage. It may also be used for other conditions involving blood clots, such as pulmonary embolism and ischemic stroke.

Tenecteplase is a recombinant tissue-type plasminogen activator that converts plasminogen to plasmin. This action leads to the degradation of fibrin clots, helping to restore blood flow in blocked vessels, particularly in the heart during a heart attack.

The dose of Tenectelex 40mg is determined by a healthcare professional based on the patient's condition and medical history. It is important to follow the prescribed dosage and administration instructions provided by your doctor.

The safety of Tenectelex 40mg during pregnancy or breastfeeding has not been established. It is important to inform your doctor if you are pregnant or breastfeeding before receiving this medication.

To order Tenectelex 40mg from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.

Tenectelex 40mg is a thrombolytic agent that is specifically designed for the treatment of acute myocardial infarction (STEMI). It has a longer half-life and more selective action compared to other thrombolytics, which may reduce the risk of bleeding complications.

Tenectelex 40mg should be stored at 2-8°C, kept refrigerated, protected from light, and not frozen or shaken. It is important to follow the storage instructions provided by the manufacturer to ensure the medication's effectiveness and safety.

Tenectelex 40mg is administered intravenously by a healthcare professional. It is given directly into a vein as soon as possible after the first signs of a heart attack. Your breathing, blood pressure, oxygen levels, and other vital signs will be closely monitored during the administration.

The most serious risks associated with Tenectelex 40mg include severe bleeding, stroke, and allergic reactions. It is important to inform your doctor immediately if you experience any unusual symptoms or side effects while receiving this medication.

Tenectelex 40mg is not suitable for everyone. It should not be used by individuals who have had a head injury or surgery on the brain or spinal cord, any current bleeding anywhere in the body, or those who have been given cardiopulmonary resuscitation for more than 2 minutes duration in the last two weeks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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