Product image of Lamisil Huidschimmelcrème (Terbinafine Hydrochloride) supplied by GNH India

Lamisil Huidschimmelcrème

Active Ingredient:
Terbinafine Hydrochloride
Origin:
EU

Lamisil Huidschimmelcrème (Terbinafine Hydrochloride)

Terbinafine, the active ingredient in Lamisil Huidschimmelcrème, is an allylamine presented as a topical cream for skin application. It is used to treat dermatophyte infections, including tinea corporis, tinea cruris, and tinea pedis, in both adult and pediatric patients.

GNH India supplies Lamisil Huidschimmelcrème as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant documentation for global distribution. Customers benefit from reliable supply chains, temperature‑controlled logistics where required, and responsive technical support.

Manufacturer / TM Owner

Karo Healthcare Ab

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Indications & Clinical Uses

Terbinafine cream is an allylamine antifungal used to treat superficial dermatophyte infections of the skin.

  • Tinea corporis: clears body ringworm lesions by inhibiting fungal growth.
  • Tinea cruris: resolves jock‑itch symptoms and eradicates the causative fungus.
  • Tinea pedis: treats athlete's foot, reducing scaling and itching.

How It Works

  • Terbinafine inhibits fungal squalene epoxidase, an enzyme essential for ergosterol synthesis in the cell membrane. This blockade leads to accumulation of toxic squalene and depletion of ergosterol, causing fungal cell membrane dysfunction and ultimately cell death, thereby eliminating the infection at the site of application.

Side Effects

Terbinafine cream is generally well tolerated, but local reactions may occur.

Common Side Effects

  • Application site irritation or burning sensation.
  • Redness or erythema at the treated area.
  • Itching or pruritus.
  • Dryness or scaling of the skin.
  • Mild stinging or tingling.
  • Localized swelling.

Serious or Rare Side Effects

  • Allergic contact dermatitis with widespread rash.
  • Severe skin reactions such as urticaria or angioedema.
  • Rare cases of Stevens‑Johnson syndrome.
  • Significant swelling or blistering at the application site.
  • Systemic hypersensitivity reactions.

Precautions & Warnings

Before using Lamisil Huidschimmelcrème, consider the following precautions.

  • Pregnancy: consult a healthcare provider; safety data are limited.
  • Breastfeeding: discuss use with a physician; limited data are available.
  • Age: use in children only as directed by a prescriber.
  • Allergy: avoid if known hypersensitivity to terbinafine or any cream excipients.
  • Concurrent antifungal therapy: inform the prescriber of any oral or topical antifungal use.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Terbinafine cream may interact with other systemic or topical agents.

Major Interactions (Avoid)

  • Oral terbinafine: concurrent use can increase systemic exposure and risk of toxicity.
  • Strong CYP450 inhibitors (e.g., oral ketoconazole): avoid combined systemic exposure.

Moderate Interactions (Monitor Closely)

  • Other topical irritants (corticosteroids, retinoids): may increase local irritation.
  • Alcohol‑based skin cleansers: can enhance dryness at the application site.
  • Phototherapy: monitor for increased photosensitivity.
  • Systemic antifungal agents: assess for overlapping toxicity.

Frequently Asked Questions

Lamisil Huidschimmelcrème is a topical cream containing terbinafine, an allylamine antifungal. It is indicated for the treatment of superficial dermatophyte infections of the skin, such as tinea corporis (body ringworm), tinea cruris (jock itch), and tinea pedis (athlete's foot).

Terbinafine inhibits the fungal enzyme squalene epoxidase, which is essential for ergosterol synthesis in the fungal cell membrane. By blocking this pathway, the drug causes toxic squalene buildup and loss of membrane integrity, leading to fungal cell death at the site of application.

The dosing regimen for Lamisil Huidschimmelcrème is determined by the prescribing healthcare professional based on the infection type, severity, patient age, and other clinical factors. Patients should follow the prescriber’s instructions and apply the cream as directed.

Safety data for topical terbinafine during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Terbinafine belongs to the allylamine class, which differs from azole antifungals that target lanosterol 14α‑demethylase. Allylamines like terbinafine often achieve rapid fungicidal activity and are effective against many dermatophytes, making them a preferred option for common skin fungal infections.

Store Lamisil Huidschimmelcrème at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct heat, and ensure the cap is tightly closed to maintain stability.

The cream should be applied to clean, dry skin in a thin layer over the affected area, usually twice daily or as directed by a healthcare professional. Hands should be washed before and after application, and the treated skin should be covered only if advised.

Although rare, serious adverse reactions can include allergic contact dermatitis, severe skin reactions such as urticaria, angioedema, or Stevens‑Johnson syndrome. Patients should discontinue use and seek immediate medical attention if they experience widespread rash, swelling, or difficulty breathing.

Individuals with a known hypersensitivity to terbinafine, any component of the cream, or other allylamine antifungals should avoid using the product. Additionally, patients should consult a healthcare provider before use if they are pregnant, breastfeeding, or taking systemic antifungal medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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