Product image of Thiomed 15mg (Thiotepa) 15mg Vials supplied by GNH India

Thiomed 15mg

Active Ingredient:
Thiotepa
Form:
Vials
Brand:
Thiomed
Origin:
India

Thiomed 15mg (Thiotepa Vials) 15mg

Thiotepa, the active ingredient in Thiomed 15mg, is an alkylating agent presented as a 15mg vial for intravenous, intramuscular, or intravesical use. It is used in the treatment of various cancers, including ovarian, bladder, and breast cancer, as well as in preparation for bone marrow transplantation.

GNH India supplies Thiomed 15mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, transplant centres, and oncology centres worldwide.

Strength

15mg

Pack Size

1s

Storage

2-8°

Manufacturer / TM Owner

Mediclone Health Care Pvt Ld

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Thiomed 15mg is an antineoplastic agent used in the treatment of various cancers. It acts by damaging the DNA of cancer cells, which slows or stops their growth and multiplication.

  • Bladder cancer: Used for superficial papillary bladder carcinoma, typically administered directly into the bladder (intravesically) to treat the tumor locally.
  • Breast cancer: Used to treat adenocarcinoma of the breast, generally through intravenous infusion.
  • Ovarian cancer: Indicated for adenocarcinoma of the ovary, typically administered intravenously.
  • Malignant effusions: Helps manage fluid buildup in body cavities caused by cancerous tumours.
  • Stem cell transplant conditioning: Used in combination with other chemotherapy drugs as part of the conditioning regimen before hematopoietic progenitor cell transplantation (HPCT).

How It Works

  • Thiotepa works by alkylating DNA, which leads to cross-linking of DNA strands and inhibition of cell division. This process interferes with the replication and transcription of DNA, ultimately leading to cell death. It is particularly effective against rapidly dividing cells, such as those found in cancerous tumours.

Side Effects

Thiomed 15mg may cause various side effects, ranging from common to serious or rare.

Common Side Effects

  • Nausea and vomiting
  • Fatigue
  • Hair loss
  • Loss of appetite
  • Diarrhea
  • Mouth sores
  • Fever
  • Injection site reactions

Serious or Rare Side Effects

  • Bone marrow depression (e.g., leucopenia, thrombocytopenia, anaemia, pancytopenia)
  • Septicaemia
  • Haemorrhage
  • Encephalopathy (high dose)
  • Secondary malignancies (e.g., myelodysplastic syndrome, acute myeloid leukaemia)
  • Hepatic veno-occlusive disease
  • Impaired fertility

Precautions & Warnings

Thiomed 15mg should be used with caution in certain patient populations and conditions. It is important to follow the prescribed dosage and administration guidelines to minimize risks.

  • Bone marrow damage: Patients with existing bone marrow damage should be monitored closely.
  • Cardiac disease: Patients with a history of cardiac disease should be carefully evaluated.
  • Prior radiation therapy: Patients who have received prior radiation therapy may be at increased risk of side effects.
  • Renal and hepatic impairment: Dosage adjustments may be necessary for patients with renal or hepatic impairment.
  • Pregnancy and lactation: Use during pregnancy and lactation should be avoided unless clearly necessary.
  • Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Thiomed 15mg may interact with other medications, which can affect its efficacy or increase the risk of side effects. It is important to inform healthcare providers about all medications being taken.

Major Interactions (Avoid)

  • Live or live-attenuated viral vaccines (e.g., yellow fever vaccine)
  • Other myelosuppressive drugs
  • Drugs that are metabolized by the liver

Moderate Interactions (Monitor Closely)

  • Anticoagulants
  • Immunosuppressants
  • Drugs that affect renal function
  • Drugs that affect hepatic function
  • Drugs that are excreted renally

Frequently Asked Questions

Thiomed 15mg is used in the treatment of various cancers, including ovarian, bladder, and breast cancer. It is also used in preparation for bone marrow transplantation and to manage malignant effusions caused by cancerous tumours. The active ingredient, Thiotepa, works by damaging the DNA of cancer cells, which slows or stops their growth and multiplication.

Thiotepa works by alkylating DNA, which leads to cross-linking of DNA strands and inhibition of cell division. This process interferes with the replication and transcription of DNA, ultimately leading to cell death. It is particularly effective against rapidly dividing cells, such as those found in cancerous tumours.

The dosage of Thiomed 15mg is determined by a healthcare provider based on the patient's condition, response to treatment, and other factors. It is important to follow the prescribed dosage and administration guidelines to minimize risks and ensure effective treatment.

Use of Thiomed 15mg during pregnancy and breastfeeding should be avoided unless clearly necessary. Thiotepa can cause harm to a developing fetus or nursing infant. It is important to discuss the potential risks and benefits with a healthcare provider before using this medication.

To order Thiomed 15mg from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask the buyer to confirm trade or institutional credentials and will reply with pricing, availability, shipping (including cold-chain where relevant), and the import paperwork.

Thiomed 15mg is an alkylating agent that works by damaging the DNA of cancer cells. It is used in the treatment of various cancers and in preparation for bone marrow transplantation. Compared to other chemotherapy drugs, Thiotepa may have a different side effect profile and may be used in specific clinical situations where other drugs are not effective or appropriate.

Thiomed 15mg should be stored at 2-8°C, kept refrigerated, and protected from light. It should not be frozen or shaken. Proper handling and storage are important to maintain the efficacy and safety of the medication. Follow the storage instructions provided by the manufacturer and healthcare provider.

Thiomed 15mg is administered by a healthcare professional. It can be given intravenously, intramuscularly, or intravesically, depending on the condition being treated. The administration method and dosage are determined by a healthcare provider based on the patient's specific needs and response to treatment.

The most serious risks associated with Thiomed 15mg include bone marrow depression, septicaemia, haemorrhage, encephalopathy (high dose), secondary malignancies, hepatic veno-occlusive disease, and impaired fertility. Patients should be closely monitored for these and other potential side effects during treatment.

Thiomed 15mg should not be used by patients with a known hypersensitivity to Thiotepa or any of its components. It should also be used with caution in patients with existing bone marrow damage, a history of cardiac disease, prior radiation therapy, renal or hepatic impairment, and during pregnancy and breastfeeding. Always consult a healthcare provider before using this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.