Thiotepa Injection (Thiomed)

Storage/Handling:

Store at a temperature below 30°C.

Uses of Thiotepa Injection (Thiomed):

Used in the treatment of several types of cancer such as -
#Brain tumor
#Breast cancer
#Non-small cell lung cancer
#Ovarian cancer

Product Introduction:

Thiotepa Injection is used to treat various cancers such as those affecting the brain, breast, lungs, and ovaries. Typically administered alongside other cancer medications during hematopoietic progenitor cell transplantation (HPCT), its usage may extend to treating other conditions, as determined by the doctor.

A healthcare professional usually administers Thiotepa Injection, and your doctor will determine the appropriate dosage and treatment duration based on the severity of your condition. It may take some weeks or months to observe the benefits, so it's crucial not to discontinue the injections without your doctor's guidance.

Common side effects include reduced white blood count, anemia, low blood platelets, increased liver enzymes, elevated bilirubin levels, mucosal inflammation, hemorrhage, diarrhea, blood in urine, and rash. This medicine may decrease blood cell count, making you more susceptible to infections. Regular blood tests are necessary to monitor blood cells, as well as kidney, liver, and heart function during the treatment.

Before taking Thiotepa Injection, inform your doctor about any bleeding, liver, or kidney issues, and disclose any medications you are taking. Due to potential interactions, it's essential to communicate all medicines in use. Avoid using this medicine during pregnancy or breastfeeding, and both males and females should practice effective contraception during treatment to prevent pregnancy.

Side Effects of Thiotepa Injection (Thiomed):

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them -
#Common side effects of Thioplan
#Decreased white blood cell count (neutrophils)
#Anemia (low number of red blood cells)
#Low blood platelets
#Increased liver enzymes
#Increased bilirubin in the blood
#Mucosal inflammation
#Hemorrhage
#Rash
#Diarrhea
#Blood in urine

Drug Interactions:

When different medicines interact, they can affect how well your medications work or increase the chance of serious side effects. Remember that this information might not include all possible interactions. Keep a complete list of all the products you use, including prescribed and over-the-counter medicines, herbal products, and share this list with your doctor and pharmacist. Don't change your medications or dosages without getting approval from your doctor.

How Thiotepa Injection (Thiomed) Works:

Thiotepa Injection is a type of medicine in the alkylating agents class, commonly used for treating cancer. It works by harming the DNA in cells, stopping them from dividing and growing. Although this is beneficial in halting the growth of cancer cells, it may also impact healthy cells, resulting in side effects.

How To Use Thiotepa Injection (Thiomed):

The dose of Thiotepa Injection depends on your weight, medical condition, lab results, and how well you respond to the treatment. For preventing rejection after a stem cell transplant, the dose may also consider your body size.

A healthcare professional administers Thiotepa Injection through a vein. Sometimes, it's directly injected into the tumor. If you feel pain, burning, or notice redness at the injection site, inform your doctor or nurse immediately.

When handling this drug, wear gloves and wash your hands thoroughly afterward. Avoid contact with your eyes or skin. In case the medication comes in contact with your eyes, rinse them well with water and consult your doctor. If it touches your skin, wash the area thoroughly with soap and water.

Safety Instructions For Thiotepa Injection (Thiomed):

ALCOHOL Consult your doctor It's unclear whether consuming alcohol is safe while undergoing treatment with Thiotepa Injection. It is advisable to consult your doctor for guidance.   PREGNANCY Consult your doctor Do not take Thiotepa Injection if you're pregnant. It can harm your developing baby. In very rare, life-threatening situations, your doctor might consider it, but only if the benefits outweigh the risks. Talk to your doctor for more information.   BREAST FEEDING Unsafe Do not breastfeed while taking Thiotepa Injection. It can pass into your milk and harm your baby.   Driving Unsafe Be cautious when driving or operating machinery while taking Thiotepa Injection. It can cause dizziness, headache, and blurred vision, which can affect your ability to drive safely.   LIVER Caution If you have liver problems, talk to your doctor before taking Thiotepa Injection. They may need to adjust your dose or monitor you more closely.   KIDNEY Caution Thiotepa Injection is likely safe for people with kidney problems, but talk to your doctor to be sure. They may need to adjust your dose.  

Habit Forming

No

Remember:

1. Thiotepa Injection is administered through an intravenous infusion (IV infusion) under the supervision of a doctor.

2. Regular blood tests may be conducted by your doctor to monitor your blood cell count, platelet count, and liver function.

3. In the treatment of bladder cancer, thiotepa is typically delivered into the bladder using a tube (catheter).

4. Adhere to your doctor's instructions regarding precautions, frequency of showering/bathing, and changing bandages/dressings.

5. While thiotepa is primarily used for cancer treatment, there is a potential risk of developing another form of cancer in some individuals. Discuss the risks and benefits of this medication with your doctor.

6. Thiotepa may increase susceptibility to infections or worsen existing infections. Avoid contact with individuals who have contagious infections like chickenpox, COVID-19, measles, or the flu.

7. To lower your risk of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.

FAQs:

1. Can Thiotepa Injection cause allergies?

Prior to using thiotepa, inform your doctor or pharmacist about any existing allergies to thiotepa or other substances. The product may contain inactive ingredients that can potentially trigger allergic reactions or other complications. For more details, consult with your pharmacist.

2. Are any tests required before consuming Thiotepa Injection?

While using this medication and for several weeks after your last dose, it is recommended to undergo lab and/or medical tests such as a complete blood count, kidney/liver function tests. Ensure you attend all scheduled medical and lab appointments. For additional details, consult your doctor.

3. What if I overdose on Thiotepa Injection?

In case of an overdose with serious symptoms like loss of consciousness or difficulty breathing, seek immediate medical attention. Otherwise, contact a poison control center promptly.

4. What if I miss a dose of Thiotepa Injection?

If you miss a dose, take it as soon as possible. However, if it's almost time for your next dose, skip the missed one and resume your regular dosing schedule. Avoid doubling the dose.