Product image of Tiberal 500mg (Ornidazole) 500mg Tablet supplied by GNH India

Tiberal 500mg

Active Ingredient:
Ornidazole
Form:
Tablet
Brand:
Tiberal 500mg
Origin:
Switzerland

Tiberal 500mg (Ornidazole Tablet) 500mg

Ornidazole, the active ingredient in Tiberal 500mg, is a nitroimidazole presented as a 500mg tablet for oral use. It is used to treat various infections caused by protozoa and anaerobic bacteria, including amoebiasis, giardiasis, and trichomoniasis. GNH India supplies Tiberal 500mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Tiberal 500mg is a well-established medication known for its efficacy in treating specific types of infections. It is widely used in clinical settings to address conditions caused by sensitive microorganisms.

Strength

500mg

Pack Size

10s

Storage

Ambient

Manufacturer / TM Owner

ORPHA SWISS GmBH

1
Pack/s
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Indications & Clinical Uses

Tiberal 500mg is an antiprotozoal and antimicrobial agent used to treat infections caused by protozoa and anaerobic bacteria. It is effective in managing the following conditions:

  • Amoebiasis: Treats infections caused by Entamoeba histolytica, including intestinal and extraintestinal amoebiasis.
  • Giardiasis: Effective against Giardia lamblia, which causes gastrointestinal infections.
  • Trichomoniasis: Used to treat infections caused by Trichomonas vaginalis, a common sexually transmitted infection.
  • Bacterial vaginosis: Helps manage infections caused by anaerobic bacteria in the vaginal area.
  • Anaerobic bacterial infections: Treats infections where anaerobic bacteria are the primary cause, such as in the abdominal region or oral cavity.

How It Works

  • Ornidazole, the active ingredient in Tiberal 500mg, works by being reduced in anaerobic organisms to reactive metabolites. These metabolites damage the DNA and inhibit nucleic acid synthesis of the sensitive microorganisms, leading to their death. This mechanism makes it effective against a range of protozoa and anaerobic bacteria.

Side Effects

Tiberal 500mg may cause various side effects, ranging from common to serious. Common Side Effects:

  • Nausea and vomiting
  • Headache
  • Dizziness
  • Dry mouth
  • Metallic taste in the mouth
  • Loss of appetite

Serious or Rare Side Effects

  • Allergic reactions, such as rash, itching, or swelling
  • Seizures
  • Peripheral neuropathy
  • Leukopenia (low white blood cell count)
  • Hepatic dysfunction (liver problems)

Precautions & Warnings

Tiberal 500mg should be used with caution and under medical supervision. Important precautions include:

  • Avoid alcohol during treatment: Consuming alcohol can cause severe reactions, including nausea, vomiting, and headache.
  • Inform your doctor: If you have a history of epilepsy, blood disorders, or liver disease, inform your doctor before starting treatment.
  • Pregnancy and breastfeeding: Consult your doctor before using Tiberal 500mg if you are pregnant, planning to become pregnant, or breastfeeding.
  • Driving and operating machinery: Be cautious as Tiberal 500mg may cause dizziness or drowsiness.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Tiberal 500mg may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects. Major Interactions (Avoid):

  • Alcohol: Can cause severe reactions, including nausea, vomiting, and headache.
  • Warfarin: May enhance the anticoagulant effect, increasing the risk of bleeding.
  • Lithium: May increase the risk of lithium toxicity.

Moderate Interactions (Monitor Closely)

  • Phenobarbital: May decrease the effectiveness of Tiberal 500mg.
  • Phenytoin: May decrease the effectiveness of Tiberal 500mg.
  • Cimetidine: May increase the concentration of Ornidazole in the blood.

Frequently Asked Questions

Tiberal 500mg is used to treat infections caused by protozoa and anaerobic bacteria. It is effective against conditions such as amoebiasis, giardiasis, trichomoniasis, bacterial vaginosis, and other anaerobic bacterial infections. The medication works by damaging the DNA of these microorganisms, leading to their death.

Ornidazole, the active ingredient in Tiberal 500mg, is reduced in anaerobic organisms to reactive metabolites. These metabolites damage the DNA and inhibit nucleic acid synthesis of the sensitive microorganisms, effectively killing them. This mechanism makes it useful against a range of protozoa and anaerobic bacteria.

The dosage of Tiberal 500mg is determined by a healthcare professional based on the specific condition being treated, the patient's weight, and other factors. It is important to follow the prescribed dosage and complete the full course of treatment as directed by your doctor.

The safety of Tiberal 500mg during pregnancy and breastfeeding should be discussed with a healthcare provider. It is generally not recommended during the first trimester of pregnancy and should be used with caution in breastfeeding mothers. Always consult your doctor for personalized advice.

To order Tiberal 500mg from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will then provide pricing, availability, shipping details, and the necessary import paperwork.

Tiberal 500mg is a nitroimidazole antibiotic, similar to other medications in its class such as metronidazole. It is effective against a range of protozoa and anaerobic bacteria. The choice between Tiberal 500mg and other antiprotozoal medications depends on the specific infection, patient factors, and the prescribing doctor's recommendation.

Tiberal 500mg should be stored below 25°C, in the original pack, and protected from moisture. It is important to keep the medication out of reach of children and to follow the storage instructions provided on the packaging to ensure its effectiveness and safety.

Tiberal 500mg is administered orally, typically after a meal. The dosage and duration of treatment are determined by a healthcare professional based on the specific condition being treated. It is important to follow the prescribed dosage and complete the full course of treatment as directed.

The most serious risks associated with Tiberal 500mg include allergic reactions, seizures, peripheral neuropathy, leukopenia, and hepatic dysfunction. If you experience any severe side effects or symptoms such as rash, itching, swelling, seizures, or signs of liver problems, seek immediate medical attention.

Tiberal 500mg should not be used by individuals with a known hypersensitivity to Ornidazole or other nitroimidazoles. It should also be used with caution in patients with a history of epilepsy, blood disorders, or liver disease. Pregnant women, especially in the first trimester, and breastfeeding mothers should consult their doctor before using Tiberal 500mg.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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