Product image of Tisseel Lyo (Aprotinin, Human Fibrinogen, Calcium Chloride Dihydrate, Human Thrombin, Human Coagulation Factor Xi) supplied by GNH India

Tisseel Lyo

Active Ingredient:
Aprotinin, Human Fibrinogen, Calcium Chloride Dihydrate, Human Thrombin, Human Coagulation Factor Xi
Origin:
EU

Tisseel Lyo (Aprotinin, Human Fibrinogen, Calcium Chloride Dihydrate, Human Thrombin, Human Coagulation Factor Xi)

Tisseel Lyo is a fibrin sealant used in surgical procedures to help control bleeding and promote tissue sealing. It combines human fibrinogen and thrombin to form a stable clot. Ideal for epilesional use, it supports wound healing in various medical settings.

Manufacturer / TM Owner

Baxter D.O.O.

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Indications & Clinical Uses

  • Tisseel Lyo is used in surgical procedures where standard techniques are insufficient for controlling bleeding. It helps seal tissues and promotes wound healing by mimicking the final stage of the blood coagulation cascade. Commonly used in cardiac, vascular, and general surgeries, it supports hemostasis and tissue adhesion. Patients often ask, 'what is Tisseel Lyo used for' in procedures requiring precise tissue sealing.

Side Effects

  • When applied, Tisseel Lyo forms a fibrin clot that adheres to tissue surfaces, providing temporary mechanical support during healing. The product mimics the body’s natural clotting process, helping to reduce minor oozing and stabilize surgical sites. Its effects are localized to the application area, with no systemic impact expected.

Precautions & Warnings

  • Handle Tisseel Lyo with care, as it is derived from human blood components and may carry a risk of transmitting infectious agents. Store the product as directed, typically refrigerated, and avoid freezing. Use only as prescribed by a healthcare professional. Discard any unused portion after opening to maintain sterility.

Avoid Interactions

  • Tisseel Lyo is a biological product and does not interact with medications in the traditional sense. However, avoid mixing with other hemostatic agents or solutions containing alcohol, as this may affect its efficacy. Always inform your healthcare provider about all medications and treatments you are using before application.

Frequently Asked Questions

Tisseel Lyo is used in surgical procedures to help control bleeding and promote tissue sealing where standard methods are insufficient.

It is applied directly to the surgical site using a specialized applicator system as directed by a healthcare professional.

It is typically used in procedures where precise tissue sealing and hemostasis are required, such as cardiac or vascular surgeries.

It is derived from human blood components, so it may not be suitable for individuals with known allergies to blood products.

Tisseel Lyo is available through licensed medical suppliers and pharmacies with a prescription.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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