Product image of TOPROL-XL 25 mg ER (Metoprolol Succinate) 25mg Tablet supplied by GNH India

TOPROL-XL 25 mg ER

Active Ingredient:
Metoprolol Succinate
Form:
Tablet
Brand:
TOPROL-XL ER
Origin:
USA

TOPROL-XL 25 mg ER (Metoprolol Succinate Tablet) 25mg

Metoprolol succinate, the active ingredient in TOPROL-XL 25 mg ER, is a beta blocker presented as a 25 mg extended-release tablet for oral use. It is used to treat hypertension, angina pectoris, and heart failure in adults. GNH India supplies TOPROL-XL 25 mg ER as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

GNH India is a trusted supplier of high-quality pharmaceuticals, ensuring that TOPROL-XL 25 mg ER meets international standards and regulatory requirements.

Strength

25mg

Pack Size

100s

Storage

Ambient

Manufacturer / TM Owner

MELINTA THERAPEUTICS INC

1
Pack/s
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Indications & Clinical Uses

TOPROL-XL 25 mg ER is a beta blocker used to manage cardiovascular conditions. It is prescribed for the following indications:

  • Hypertension: Reduces blood pressure by decreasing the heart's workload.
  • Angina pectoris: Helps prevent chest pain by improving blood flow to the heart.
  • Heart failure: Improves heart function and reduces symptoms in patients with chronic heart failure.

How It Works

  • Metoprolol succinate works by selectively blocking beta-1 adrenergic receptors in the heart. This action decreases heart rate, myocardial contractility, and cardiac output, thereby reducing myocardial oxygen demand and improving heart function in conditions like hypertension, angina, and heart failure.

Side Effects

TOPROL-XL 25 mg ER may cause various side effects, ranging from common to serious. Common Side Effects:

  • Fatigue: Feeling unusually tired or weak.
  • Dizziness: A sensation of lightheadedness or unsteadiness.
  • Nausea: A feeling of sickness in the stomach.
  • Shortness of breath: Difficulty breathing or feeling breathless.

Serious or Rare Side Effects

  • Bradycardia: An abnormally slow heart rate.
  • Hypotension: Abnormally low blood pressure.
  • Worsening heart failure: Transient worsening of heart failure symptoms.
  • Allergic reactions: Rash, itching, or swelling.

Precautions & Warnings

TOPROL-XL 25 mg ER should be used with caution and under medical supervision. Important precautions include:

  • Avoid sudden discontinuation: Suddenly stopping the medication can worsen conditions like angina or heart failure.
  • Monitor heart rate and blood pressure: Regular check-ups are essential to adjust the dosage as needed.
  • Inform your doctor about other medications: Some drugs may interact with TOPROL-XL 25 mg ER.
  • Avoid alcohol: It can enhance the side effects of the medication.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

TOPROL-XL 25 mg ER may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects. Major Interactions (Avoid):

  • Calcium channel blockers: May cause severe hypotension or bradycardia.
  • Antiarrhythmic drugs: Can enhance the risk of heart block.
  • Monoamine oxidase inhibitors: May lead to severe hypertension.

Moderate Interactions (Monitor Closely)

  • Nonsteroidal anti-inflammatory drugs (NSAIDs): May reduce the blood pressure-lowering effect.
  • Diabetes medications: May mask symptoms of hypoglycemia.
  • Antidepressants: May exacerbate depressive symptoms.

Frequently Asked Questions

TOPROL-XL 25 mg ER is used to treat hypertension, angina pectoris, and heart failure. It works by reducing heart rate and blood pressure, improving heart function, and preventing chest pain.

Metoprolol succinate is a beta blocker that selectively blocks beta-1 adrenergic receptors in the heart. This action decreases heart rate, myocardial contractility, and cardiac output, reducing myocardial oxygen demand and improving heart function.

The usual initial dose of TOPROL-XL 25 mg ER is determined by the prescribing doctor based on the patient's condition. The dosage may be gradually increased at weekly intervals until the desired therapeutic effect is achieved.

TOPROL-XL 25 mg ER is classified as a pregnancy category C drug, meaning it should be used during pregnancy only if the potential benefits outweigh the risks. It is not recommended for use during breastfeeding without consulting a healthcare provider.

To order TOPROL-XL 25 mg ER from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.

TOPROL-XL 25 mg ER is an extended-release formulation of metoprolol succinate, designed to provide a steady release of the medication over 24 hours. This can result in more consistent blood levels and fewer side effects compared to immediate-release formulations.

TOPROL-XL 25 mg ER should be stored below 25°C, kept in the original pack, and protected from moisture. It should be kept out of reach of children and pets, and any unused or expired medication should be disposed of properly.

TOPROL-XL 25 mg ER is taken orally, usually once daily, with or without food. The tablet should be swallowed whole and not crushed, chewed, or broken to ensure the extended-release mechanism works properly.

The most serious risks associated with TOPROL-XL 25 mg ER include severe hypotension, bradycardia, worsening heart failure, and allergic reactions. Patients should seek immediate medical attention if they experience symptoms such as severe dizziness, fainting, or difficulty breathing.

TOPROL-XL 25 mg ER should not be used by individuals with certain medical conditions, such as severe bradycardia, heart block, or uncontrolled heart failure. It should also be avoided by patients with a known allergy to metoprolol or any of the excipients in the formulation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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