Product image of Trikafta 80mg/40mg/60mg (Elexacaftor + Tezacaftor+ Ivacaftor+ Ivacaftor Oral Granules) 80mg/40mg/60mg + 59.5MG GRANULE supplied by GNH India

Trikafta 80mg/40mg/60mg

Active Ingredient:
Elexacaftor + Tezacaftor+ Ivacaftor+ Ivacaftor Oral Granules
Form:
GRANULE
Brand:
Trikafta
Origin:
Portugal

Trikafta 80mg/40mg/60mg (Elexacaftor + Tezacaftor+ Ivacaftor+ Ivacaftor Oral Granules) 80mg/40mg/60mg + 59.5MG

Trikafta 80mg/40mg/60mg oral granules combine elexacaftor, tezacaftor, and ivacaftor to support cystic fibrosis treatment. This cystic fibrosis transmembrane conductance regulator modulator therapy is designed for daily use in eligible patients. Store below 25°C and protect from moisture.

Strength

80mg/40mg/60mg + 59.5MG

Pack Size

56s

Storage

Below 25°C

Manufacturer / TM Owner

Vertex Pharmaceuticals Incorporated

1
Pack/s
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Indications & Clinical Uses

  • Trikafta oral granules are used to treat cystic fibrosis in patients aged 6 and older with specific gene mutations. The combination therapy helps improve lung function and reduce symptoms by enhancing CFTR protein function. It is prescribed for those with at least one F508del mutation or other responsive mutations. This medication is part of a long-term management plan for cystic fibrosis.

Side Effects

  • Common effects of Trikafta may include headache, upper respiratory tract infection, and abdominal pain. Some users report improved breathing and reduced coughing over time. Digestive discomfort and nausea are occasionally noted. These effects vary by individual and should be monitored by a healthcare provider.

Precautions & Warnings

  • Keep Trikafta oral granules in their original packaging until use to protect from moisture. Store below 25°C and avoid exposure to high humidity. Do not use if the granules appear discolored or clumped. Consult a healthcare professional before starting or stopping this medication.

Avoid Interactions

  • Trikafta may interact with strong CYP3A inducers like rifampin or St. John’s wort, reducing effectiveness. Avoid grapefruit products, as they can increase drug levels. Hormonal contraceptives may be less effective; use alternative birth control methods. Always inform your doctor about all medications and supplements in use.

References

Frequently Asked Questions

Trikafta is used to treat cystic fibrosis in patients with specific gene mutations, such as F508del.

Store Trikafta below 25°C in the original packaging to protect from moisture.

Avoid grapefruit products while taking Trikafta, as they may increase side effects.

Do not use Trikafta if you are allergic to any of its components or have severe liver problems.

Trikafta is a brand-name medication; generic versions may not be available.

Published by GNH India Pharmaceuticals Limited

Last updated:

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