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Uman Big

Active Ingredient:
Human Hepatitis B Immunoglobulin
Origin:
EU

Uman Big (Human Hepatitis B Immunoglobulin)

Uman Big is a Human Hepatitis B Immunoglobulin used for post-exposure prophylaxis and treatment of hepatitis B virus infection. This immunoglobulin provides passive immunity by supplying antibodies against the virus. It is administered intramuscularly and is derived from human plasma. Ideal for patients requiring immediate protection.

Manufacturer / TM Owner

Kedrion S.P.A.

1
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Indications & Clinical Uses

  • Human Hepatitis B Immunoglobulin, like Uman Big, is used to prevent hepatitis B infection after exposure, such as needlestick injuries or mucosal contact with infected blood. It is also used for infants born to hepatitis B-positive mothers to prevent vertical transmission. Additionally, it may be used in immunocompromised individuals or those awaiting liver transplants to provide temporary protection against the virus.

Side Effects

  • Uman Big works by providing pre-formed antibodies that bind to the hepatitis B virus, neutralizing its ability to infect cells. This passive immunity offers immediate but temporary protection, typically lasting a few weeks to months. Patients may experience mild discomfort at the injection site, such as redness or swelling. Some individuals might feel general fatigue or headache after administration.

Precautions & Warnings

  • Uman Big should be stored refrigerated but not frozen, and protected from light. It is important to inspect the solution for particles or discoloration before use. Patients with a history of severe allergic reactions to blood products should use this medication with caution. Always inform healthcare providers about any known allergies or medical conditions before receiving this immunoglobulin.

Avoid Interactions

  • Uman Big may interact with live vaccines, potentially reducing their effectiveness. It is generally recommended to avoid live vaccines for at least 3 months after receiving this immunoglobulin. No significant interactions with other medications have been widely reported, but always disclose all medications and supplements to your healthcare provider. Alcohol and certain foods do not typically interfere with the action of this medication.

Frequently Asked Questions

It is used to prevent hepatitis B infection after exposure or in high-risk individuals, such as newborns of infected mothers.

Uman Big is administered via intramuscular injection, typically in the upper arm or thigh.

Patients with a history of severe allergic reactions to blood products should consult their healthcare provider before use.

The passive immunity provided by Uman Big typically lasts a few weeks to months, depending on the dose and individual response.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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