Acebutolol Hydrochloride (Acebutolol Hydrochloride)

Trade Name : Acebutolol Hydrochloride

Mylan Pharmaceuticals Inc.

CAPSULE

Strength 200 mg/1

ACEBUTOLOL HYDROCHLORIDE Adrenergic beta-Antagonists [MoA],beta-Adrenergic Blocker [EPC]

Delivery Process

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Product information is meant for

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Acebutolol Hydrochloride (Acebutolol Hydrochloride) which is also known as Acebutolol Hydrochloride and Manufactured by Mylan Pharmaceuticals Inc.. It is available in strength of 200 mg/1 per ml. Read more

Acebutolol Hydrochloride (Acebutolol Hydrochloride) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Acebutolol hydrochloride is a selective, hydrophilic beta-adrenoreceptor blocking agent with mild intrinsic sympathomimetic activity for use in treating patients with hypertension and ventricular arrhythmias. It is marketed in capsule form for oral administration. Acebutolol Hydrochloride Capsules, USP are available in two strengths which contain 200 mg or 400 mg of acebutolol as the hydrochloride salt. The inactive ingredients are povidone, pregelatinized starch and stearic acid. The empty gelatin capsules contain D&C Red No. 28, D&C Yellow No. 10, FD&C Blue No. 1, FD&C Red No. 40, gelatin, sodium lauryl sulfate and titanium dioxide. In addition, the imprinting ink contains black iron oxide, D&C Yellow No. 10 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake, FD&C Blue No. 2 Aluminum Lake, FD&C Red No. 40 Aluminum Lake, propylene glycol and shellac glaze.
  • Acebutolol hydrochloride, USP is a white or slightly off-white powder freely soluble in water, and less soluble in alcohol. Chemically it is defined as the hydrochloride salt of (u00b1) N-[3-Acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl] butanamide.
  • Acebutolol is a cardioselective, beta-adrenoreceptor blocking agent, which possesses mild intrinsic sympathomimetic activity (ISA) in its therapeutically effective dose range.
  • No data
  • Acebutolol hydrochloride capsules are contraindicated in: 1) persistently severe bradycardia; 2) second- and third-degree heart block; 3) overt cardiac failure; and 4) cardiogenic shock (see ).
  • No data
  • No data
  • Acebutolol is well tolerated in properly selected patients. Most adverse reactions have been mild, not required discontinuation of therapy, and tended to decrease as duration of treatment increases.
  • The following table shows the frequency of treatment-related side effects derived from controlled clinical trials in patients with hypertension, angina pectoris, and arrhythmia. These patients received acebutolol, propranolol, or hydrochlorothiazide as monotherapy, or placebo.
  • The following selected (potentially important) side effects were seen in up to 2% of acebutolol patients:
  • Arrayn- Cardiovascular:
  • Arrayn- Central Nervous System
  • Arrayn- Dermatological:
  • Arrayn- Gastrointestinal:
  • Arrayn- Genitourinary:
  • Arrayn- Liver and Biliary System:
  • Arrayn- Musculoskeletal:
  • Arrayn- Respiratory:
  • Arrayn- Special Senses:
  • Arrayn- Autoimmune:
  • The incidence of drug-related adverse effects (volunteered and solicited) according to acebutolol dose is shown below. (Data from 266 hypertensive patients treated for 3 months on a constant dose.)
  • In addition, certain adverse effects not listed above have been reported with other beta-blocking agents and should also be considered as potential adverse effects of acebutolol.
  • No specific information on emergency treatment of overdosage is available for acebutolol. However, overdosage with other beta-blocking agents has been accompanied by extreme bradycardia, advanced atrioventricular block, intraventricular conduction defects, hypotension, severe congestive heart failure, seizures, and in susceptible patients, bronchospasm and hypoglycemia. Although specific information on the emergency treatment of acebutolol overdose is not available, on the basis of the pharmacological actions and the observations in treating overdoses with other beta-blockers, the following general measures should be considered:
  • Acebutolol is dialyzable.
  • No data
  • Acebutolol Hydrochloride Capsules, USP are available containing 200 mg or 400 mg of acebutolol as the hydrochloride salt.
  • The 200 mg capsule is a hard-shell gelatin capsule with a medium orange opaque cap and medium orange opaque body filled with a white powder blend. The capsule is axially printed with over in black ink on both the cap and the body. They are available as follows:
  • NDC 0378-1200-01bottles of 100 capsules
  • The 400 mg capsule is a hard-shell gelatin capsule with a medium orange opaque cap and medium orange opaque body filled with a white powder blend. The capsule is axially printed with over in black ink on both the cap and the body. They are available as follows:
  • NDC 0378-1400-01bottles of 100 capsules
  • Store at 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F). [See USP Controlled Room Temperature.]
  • Protect from light.
  • Keep container tightly closed.
  • Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.
  • Mylan Pharmaceuticals Inc.
  • REVISED SEPTEMBER 2012ACEB:R10
  • NDC 0378-1200-01
  • Acebutololn- Hydrochloriden- Capsules, USPn- 200 mg*
  • Rx onlyu00a0u00a0u00a0u00a0u00a0100 Capsules
  • *Each capsule contains acebutololhydrochloride, USP equivalent to200 mg of acebutolol.
  • Dispense in a tight, light-resistantcontainer as defined in the USPusing a child-resistant closure.
  • Keep container tightly closed.
  • Keep this and all medicationn- out of the reach of children.
  • Store at 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F).n- [See USP Controlled Roomn- Temperature.]
  • Protect from light.
  • Usual Dosage:
  • Mylan Pharmaceuticals Inc.
  • Mylan.com
  • RM1200A5
  • NDC 0378-1400-01
  • Acebutololn- Hydrochloriden- Capsules, USPn- 400 mg*
  • Rx onlyu00a0u00a0u00a0u00a0u00a0100 Capsulesu00a0
  • *Each capsule contains acebutololhydrochloride, USP equivalent to400 mg of acebutolol.
  • Dispense in a tight, light-resistantcontainer as defined in the USPusing a child-resistant closure.
  • Keep container tightly closed.
  • Keep this and all medicationn- out of the reach of children.
  • Store at 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F).n- [See USP Controlled Roomn- Temperature.]
  • Protect from light.
  • Usual Dosage:
  • Mylan Pharmaceuticals Inc.
  • Mylan.com
  • RM1400A5

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