Alclometasone Dipropionate (Alclometasone Dipropionate)

Trade Name : Alclometasone Dipropionate

E. Fougera & Co. a division of Fougera Pharmaceuticals Inc.

OINTMENT

Strength 0.5 mg/g

ALCLOMETASONE DIPROPIONATE Corticosteroid [EPC],Corticosteroid Hormone Receptor Agonists [MoA]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Alclometasone Dipropionate (Alclometasone Dipropionate) which is also known as Alclometasone Dipropionate and Manufactured by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc.. It is available in strength of 0.5 mg/g per ml. Read more

Alclometasone Dipropionate (Alclometasone Dipropionate) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • No data
  • Alclometasone dipropionate ointment contains alclometasone dipropionate (7u03b1-chloro-11u03b2 ,17,21-trihydroxy-16u03b1 -methylpregna-1,4-diene-3,20-dione 17,21-dipropionate), a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents. Chemically, alclometasone dipropionate is CHClO. It has the following structural formula:
  • Alclometasone dipropionate has the molecular weight of 521. It is a white powder, insoluble in water, slightly soluble in propylene glycol, and moderately soluble in hexylene glycol. Each gram of alclometasone dipropionate ointment contains 0.5 mg of alclometasone dipropionate in an ointment base of hexylene glycol, white wax, propylene glycol stearate, and white petrolatum.
  • Like other topical corticosteroids, alclometasone dipropionate has anti-inflammatory, antipruritic, and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A.
  • Pharmacokinetics:
  • Alclometasone dipropionate ointment is a low to medium potency corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Alclometasone dipropionate ointment may be used in pediatric patients 1 year of age or older, although the safety and efficacy of drug use for longer than 3 weeks have not been established (see ). Since the safety and efficacy of alclometasone dipropionate ointment have not been established in pediatric patients below 1 year of age, the use in this age-group is not recommended.
  • Alclometasone dipropionate ointment is contraindicated in those patients with a history of hypersensitivity to any of the components in these preparations.
  • No data
  • The following local adverse reactions have been reported with alclometasone dipropionate ointment in approximately 1% of patients: itching, burning, and erythema. The following additional local adverse reactions have been reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in approximate decreasing order of occurrence: folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, skin atrophy, striae, and miliaria.
  • Topically applied alclometasone dipropionate ointment can be absorbed in sufficient amounts to produce systemic effects (see ).
  • Apply a thin film of alclometasone dipropionate ointment to the affected skin areas two or three times daily; massage gently until the medication disappears. Alclometasone dipropionate ointment may be used in pediatric patients 1 year of age or older. Safety and effectiveness of alclometasone dipropionate ointment in pediatric patients for more than 3 weeks of use have not been established. Use in pediatric patients under 1 year of age is not recommended. As with other corticosteroids, therapy should be discontinued when control is achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary. Alclometasone dipropionate ointment should not be used with occlusive dressings unless directed by a physician. Alclometasone dipropionate ointment should not be applied in the diaper area if the child still requires diapers or plastic pants as these garments may constitute occlusive dressing.
  • Alclometasone dipropionate ointment USP, 0.05% is supplied in
  • Store between 2u00b0 and 30u00b0C (36u00b0 and 86u00b0F).
  • E. FOUGERA & CO.A division of Fougera Pharmaceuticals Inc.Melville, New York 11747
  • I2264D R09/12 #77
  • PACKAGE LABEL u2013 PRINCIPAL DISPLAY PANEL u2013 15 G Container
  • Fougera n
  • ALCLOMETASONEn- DIPROPIONATE OINTMENTn- USP, 0.05%
  • Rx only
  • FOR DERMATOLOGIC USE ONLYn- NOT FOR OPHTHALMIC USE
  • WARNING:
  • NET WT 15 grams
  • PACKAGE LABEL u2013 PRINCIPAL DISPLAY PANEL u2013 15 G Carton
  • Fougera n
  • Rx only
  • ALCLOMETASONEn- DIPROPIONATE OINTMENTn- USP, 0.05%
  • FOR DERMATOLOGIC USE ONLYn- NOT FOR OPHTHALMIC USE
  • WARNING:
  • NET WT 15 grams

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