Alfentanil Hydrochloride (Alfentanil Hydrochloride)

Trade Name : Alfentanil Hydrochloride

Hospira, Inc.

INJECTION, SOLUTION

Strength 500 ug/mL

ALFENTANIL HYDROCHLORIDE Full Opioid Agonists [MoA],Opioid Agonist [EPC]

Delivery Process

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Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Alfentanil Hydrochloride (Alfentanil Hydrochloride) which is also known as Alfentanil Hydrochloride and Manufactured by Hospira, Inc.. It is available in strength of 500 ug/mL per ml. Read more

Alfentanil Hydrochloride (Alfentanil Hydrochloride) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

Read more
  • No data
  • Addiction, Abuse, and Misuse
  • Alfentanil injection exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess each patient's risk prior to prescribing alfentanil injection, and monitor all patients regularly for the development of these behaviors and conditions .
  • WARNING: ADDICTION, ABUSE, AND MISUSE
  • See full prescribing information for complete boxed warning.
  • Alfentanil injection exposes users to risks of addiction, abuse, and misuse, which can lead to overdose and death. Assess patient's risk before prescribing and monitor closely for these behaviors and conditions. ()
  • No data
  • Alfentanil injection is indicated:
  • Alfentanil injection is an opioid indicated:
  • as an analgesic adjunct given in incremental doses in the maintenance of anesthesia with barbiturate/nitrous oxide/oxygen.
  • as an analgesic administered by continuous infusion with nitrous oxide/oxygen in the maintenance of general anesthesia.
  • as a primary anesthetic agent for the induction of anesthesia in patients undergoing general surgery in which endotracheal intubation and mechanical ventilation are required.
  • as the analgesic component for monitored anesthesia care (MAC). ()
  • No data
  • Alfentanil injection should be administered only by persons specifically trained in the use of intravenous anesthetics and management of the respiratory effects of potent opioids.
  • Ensure that an opioid antagonist, resuscitative and intubation equipment, and oxygen are readily available. ().
  • Individualize dosing based on factors such as age, body weight, physical status, underlying pathological condition, use of other drugs, type of anesthesia to be used, and the surgical procedure involved. ()
  • Doses of alfentanil injection vary depending on circumstances .(see )
  • Reduce the dose of alfentanil injection in elderly, debilitated and obese patients. (, )
  • Reduce the dose of alfentanil injection when administered with CNS depressants. ()
  • Alfentanil Injection USP, for intravenous use (equivalent to 500 mcg/mL alfentanil base).
  • Solution for injection (sterile): eq. to 500 mcg/mL alfentanil base; 2 mL and 5 mL ampules. ()
  • Alfentanil injection is contraindicated in patients with:
  • Hypersensitivity to alfentanil. ()
  • No data
  • Risks of Muscle Rigidity and Skeletal Muscle Movement
  • Life-Threatening Respiratory Depression in Patients with Chronic Pulmonary Disease or in Elderly, Cachectic, and Debilitated Patients
  • Serotonin Syndrome
  • Risks of Use in Patients with Increased Intracranial Pressure, Brain Tumors, and Head Injury
  • The following serious adverse reactions are described, or described in greater detail, in other sections:
  • Most common adverse reactions were apnea, rigidity, and bradycardia. ()
  • To report SUSPECTED ADVERSE REACTIONS, contact Pfizer, Inc. at 1-800-438-1985 or FDA at 1-800-FDA-1088 or .
  • Table 2 includes clinically significant drug interactions with alfentanil injection.
  • Concomitant Use of CNS Depressants
  • Mixed Agonist/Antagonist and Partial Agonist Opioid Analgesics
  • No data
  • Pregnancy
  • Lactation
  • No data
  • No data
  • Alfentanil Injection, USP contains alfentanil, an opioid agonist, chemically designated as N- [1- [2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1- yl) ethyl]-4-(methoxymethyl)-4-piperidinyl]-N-phenylpropanamide monohydrochloride (1:1) with a molecular weight of 452.98 and an n-octanol: water partition coefficient of 128:1 at pH 7.4. The structural formula of Alfentanil HCl is:
  • Alfentanil Injection, USP is a sterile, non-pyrogenic, preservative free aqueous solution containing alfentanil hydrochloride equivalent to 500 mcg per mL of alfentanil base for intravenous injection. The solution, which contains sodium chloride for isotonicity, has a pH range of 4.0 to 6.0. Each mL contains:
  • Active: Alfentanil base 500 mcg.
  • Inactive: Sodium Chloride 9 mg and Water for Injection q.s.
  • No data
  • No data
  • No data
  • Distributed byHospira, Inc., Lake Forest, IL 60045 USALAB-1059-2.0
  • 2 mL n ampul
  • Alfentanil Inj., USP1000 mcg/2 mL(500 mcg/mL)
  • CII
  • Rxn- Hospira
  • NDC 0409-2266-02Hospira, Inc.Lake Forest, IL 60045 USA
  • IM-0831 (10/04)
  • RL-0833 (10/04)
  • CII
  • NDC 0409-2266-02
  • 2 mLn- Discard unused portion
  • Alfentanil Inj., USP1000 mcg/2 mL (500 mcg/mL)
  • May be habit forming.
  • For I.V. use.
  • Rx
  • Hospira, Inc., Lake Forest, IL 60045 USA
  • Single-dose
  • 10-2 mL ampuls
  • NDC 0409-2266-02
  • Discard unused portion
  • Alfentanil Injection, USP1000 mcg/2 mL(500 mcg/mL)
  • CII
  • Warning: May be habit forming.
  • For Intravenous Use.
  • Rx only
  • Hospira, Inc., Lake Forest, IL 60045 USA
  • Hospira
  • NDC 0409-2266-05
  • 5 mL Single-doseDiscard unused portion
  • CII
  • Alfentanil Inj., USP 2500 mcg/5 mL
  • (500 mcg/mL)
  • May be habit forming.For I.V. use. Store at 20 to 25u00b0C (68 to 77u00b0F). [See USP Controlled Room Temperature.] Protect from light. Hospira, Inc. Lake Forest, IL 60045 USA
  • Rx only
  • Hospira
  • Single-dose10-5 mL ampuls NDC 0409-2266-05
  • Discard unused portion
  • Alfentanil Injection, USP 2500 mcg/5 mL
  • (500 mcg/mL)
  • Warning: May be habit forming. For Intravenous Use.
  • CII
  • Rx only
  • Hospira

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