Amlodipine Besylate And Benazepril Hydrochloride (Amlodipine Besylate And Benazepril Hydrochloride)

Trade Name : Amlodipine Besylate and Benazepril Hydrochloride

Aidarex Pharmaceuticals LLC

CAPSULE

Strength 510 mg/1mg/1

AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE Calcium Channel Antagonists [MoA],Dihydropyridine Calcium Channel Blocker [EPC],Dihydropyridines [CS],Angiotensin Converting Enzyme Inhibitor [EPC],Angiotensin-converting Enzyme Inhibitors [MoA],Decreased Blood Pressure [PE]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Amlodipine Besylate And Benazepril Hydrochloride (Amlodipine Besylate And Benazepril Hydrochloride) which is also known as Amlodipine Besylate and Benazepril Hydrochloride and Manufactured by Aidarex Pharmaceuticals LLC. It is available in strength of 5; 10 mg/1; mg/1 per ml. Read more

Amlodipine Besylate And Benazepril Hydrochloride (Amlodipine Besylate And Benazepril Hydrochloride) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • WARNING: n
  • When pregnancy is detected, discontinue amlodipine besylate and benazepril hydrochloride as soon as possible (n- Arrayn- ). Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus ()
  • WARNING: n
  • See full prescribing information for complete boxed warning
  • When pregnancy is detected, discontinue amlodipine besylate and benazepril hydrochloride as soon as possible (). Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus ()
  • Boxed Warning: Fetal Toxicityu00a0 u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0 01/2012
  • Dosage and Administration u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0 10/2012
  • Contraindications u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0 10/2012
  • Warnings and Precautions: Fetal Toxicity () u00a0u00a0u00a0u00a0u00a0u00a0 u00a0u00a0 01/2012
  • Amlodipine besylate and benazepril hydrochloride capsules are indicated for the treatment of hypertension in patients not adequately controlled on monotherapy with either agent.
  • Amlodipine besylate and benazepril hydrochloride capsules is a combination capsule of amlodipine, a dihydropyridine calcium channel blocker (DHP CCB) and benazepril, an angiotensin converting enzyme (ACE) inhibitor. Amlodipine besylate and benazepril hydrochloride capsules are indicated for the treatment of hypertension in patients not adequately controlled on monotherapy with either agent ()
  • No data
  • Dose once-daily
  • May be used as add-on therapy for patients not adequately controlled with either a dihydropyridine calcium channel blocker or an ACE inhibitor )
  • Patients who experience edema with amlodipine may be switched to amlodipine besylate and benazepril hydrochloride capsules containing a lower dose of amlodipine ()
  • Start amlodipine besylate and benazepril hydrochloride capsules at 2.5/10 mg in patients u226575 years old or in patients with hepatic impairment ()
  • Amlodipine besylate and benazepril hydrochloride capsules are available as follows:
  • 2.5/10 mg, 5/10 mg, 5/20 mg, 5/40 mg, 10/20 mg, and 10/40 mg.
  • Capsules (amlodipine/benazepril mg): 2.5/10, 5/10, 5/20, 5/40, 10/20, 10/40 ()
  • No data
  • Do not co-administer aliskiren with ARBs or ACEIs, including amlodipine besylate and benazepril hydrochloride in patients with diabetes n
  • Amlodipine besylate and benazepril hydrochloride is contraindicated in patients with a history of angioedema, with or without previous ACE inhibitor treatment, or patients who are hypersensitive to benazepril, to any other ACE inhibitor, or to amlodipine. n
  • No data
  • Watch for anaphylactoid reactions, including angioedema (head, neck or intestinal). n
  • Warn patients with severe obstructive coronary artery disease about the risk of myocardial infarction or increased angina ()
  • Assess for hypotension and hyperkalemia ( and )
  • Avoid fetal or neonatal exposure ()
  • Titrate slowly in patients with impaired hepatic () or severely impaired renal () function.
  • Discontinuation because of adverse reactions occurred in 4% of amlodipine besylate and benazepril hydrochloride-treated patients and 3% of placebo-treated patients. The most common reasons for discontinuation of therapy with amlodipine besylate and benazepril hydrochlorideu00a0 were cough and edema. ()
  • Simvastatin:
  • CYP3A4 Inhibitors:
  • CYP3A4 Inducers
  • :
  • Benazepril
  • Potassium Supplements and Potassium-Sparing Diuretics:
  • Lithium:
  • Gold:
  • Non-Steroidal Anti-Inflammatory Agents including Selective Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors):
  • The antihypertensive effect of ACE inhibitors, including benazepril, may be attenuated by NSAIDs.u00a0
  • Antidiabetic agents:
  • Dual Blockade of the Renin-Angiotensin System (RAS):
  • Do not co-administer aliskiren with amlodipine besylate and benazepril hydrochloride in patients with diabetes. Avoid use of aliskiren with amlodipine besylate and benazepril hydrochloride in patients with renal impairment (GFR <60 ml/min).
  • Potassium supplements / Potassium-sparing diuretics: risk of hyperkalemia n
  • Lithium: Increased serum lithium levels; toxicity symptoms (n
  • Injectable gold: facial flushing, nausea, vomiting, or hypotension may occur n
  • NSAID: Risk of renal dysfunction, loss of antihypertensive effect ().
  • If simvastatin is co-administered with amlodipine, do not exceed doses greater than 20 mg daily of simvastatin ()
  • Nursing Mothers:
  • 8.3
  • Only a few cases of human overdose with amlodipine have been reported. One patient was asymptomatic after a 250 mg ingestion; another, who combined 70 mg of amlodipine with an unknown large quantity of a benzodiazepine, developed refractory shock and died.u00a0
  • Human overdoses with any combination of amlodipine and benazepril have not been reported. In scattered reports of human overdoses with benazepril and other ACE inhibitors, there are no reports of death.u00a0
  • Arrayn- Treatment:
  • In the event of a potentially life-threatening oral overdose, use induction of vomiting or gastric lavage and/or activated charcoal to remove the drug from the gastrointestinal tract (only if presented within 1 hour after ingestion of amlodipine besylate and benazepril hydrochloride).
  • Other clinical manifestations of overdose should be managed symptomatically based on modern methods of intensive care.
  • To obtain up-to-date information about the treatment of overdose, a good resource is your certified Regional Poison-Control Center. Telephone numbers of certified poison-control centers are listed in the Physiciansu2019 Desk Reference (PDR). In managing overdose, consider the possibilities of multiple-drug overdoses, drug-drug interactions, and unusual drug kinetics in your patient.
  • The most likely effect of overdose with amlodipine besylate and benazepril hydrochloride is vasodilation, with consequent hypotension and tachycardia. Simple repletion of central fluid volume (Trendelenburg positioning, infusion of crystalloids) may be sufficient therapy, but pressor agents (norepinephrine or high-dose dopamine) may be required. With abrupt return of peripheral vascular tone, overdoses of other dihydropyridine calcium channel blockers have sometimes progressed to pulmonary edema, and patients must be monitored for this complication.
  • Analyses of bodily fluids for concentrations of amlodipine, benazepril, or their metabolites are not widely available. Such analyses are, in any event, not known to be of value in therapy or prognosis.
  • No data are available to suggest physiologic maneuvers (e.g., maneuvers to change the pH of the urine) that might accelerate elimination of amlodipine, benazepril, or their metabolites. Benazeprilat is only slightly dialyzable; attempted clearance of amlodipine by hemodialysis or hemo-perfusion has not been reported, but amlodipineu2019s high protein binding makes it unlikely that these interventions will be of value.
  • Angiotensin II could presumably serve as a specific antagonist-antidote to benazepril, but angiotensin II is essentially unavailable outside of scattered research laboratories.
  • Amlodipine besylate and benazepril hydrochloride capsules is a combination of amlodipine besylate and benazepril hydrochloride.u00a0Benazepril hydrochloride is a white to off-white crystalline powder, soluble (>100 mg/mL) in water, in ethanol, and in methanol. Benazepril hydrochlorideu2019s chemical name is 3-[[1-(ethoxycarbonyl)-3-phenyl-(1S)- propyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-(3S)-benzazepine-1-acetic acid monohydrochloride; its structural formula is
  • Its molecular formula is CHN0u2022HCl, and its molecular weight is 460.96.u00a0
  • Benazeprilat, the active metabolite of benazepril, is a nonsulfhydryl angiotensin-converting enzyme (ACE) inhibitor. Benazepril is converted to benazeprilat by hepatic cleavage of the ester group.u00a0Amlodipine besylate is a white to pale yellow crystalline powder, slightly soluble in water and sparingly soluble in ethanol. Its chemical name is (R,S)3-ethyl-5-methyl-2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-1,4- dihydro-6-methyl-3,5-pyridinedicarboxylate benzenesulfonate; its structural formula is
  • Its molecular formula is CHClN0u2022CH0S, and its molecular weight is 567.1.u00a0
  • Amlodipine besylate and benazepril hydrochloride capsules are formulated in six different strengths for oral administration with a combination of amlodipine besylate equivalent to 2.5 mg, 5 mg or 10 mg of amlodipine, with 10 mg, 20 mg or 40 mg of benazepril hydrochloride providing for the following available combinations: 2.5 mg/10 mg, 5 mg/10 mg, 5 mg/20 mg,5 mg/40 mg, 10 mg/20 mg and 10 mg/40 mg.
  • The inactive ingredients of the capsules are colloidal silicon dioxide, crospovidone, hydrogenated castor oil, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, sodium starch glycolate and talc. Each hard-gelatin capsule contains gelatin, sodium lauryl sulfate, titanium dioxide, D&C yellow # 10 and D&C red # 28, (5 mg/20 mg, 10 mg/40 mg), u00a0FD&C blue # 1 and FD&C red # 40 (5 mg/20 mg, 5 mg/40 mg),u00a0 FD & C Yellow 6 (5 mg/40 mg), FD&C green # 3 (2.5 mg/10 mg), iron oxide black (10 mg/20 mg) and iron oxide red (5 mg/20 mg and 10 mg/20 mg ) as coloring agents.
  • No data
  • No data
  • Over 950 patients received amlodipine besylate and benazepril hydrochloride once daily in six double-blind, placebo-controlled studies. The antihypertensive effect of a single dose persisted for 24 hours, with peak reductions achieved 2-8 hours after dosing.u00a0
  • Once-daily doses of benazepril/amlodipine using benazepril doses of 10 mg to 20 mg and amlodipine doses of 2.5 mg to 10 mg decreased seated pressure (systolic/diastolic) 24 hours after dosing by about 10-25/6-13 mmHg.
  • u00a0In two studies in patients not adequately controlled on either benazepril 40 mg alone (n=329) or amlodipine 10 mg alone (n=812) once daily doses of amlodipine besylate and benazepril hydrochloride u00a010/40 mg further decreased seated blood pressure compared to the respective monotherapy alone.u00a0
  • Combination therapy was effective in blacks and nonblacks. Both components contributed to the antihypertensive efficacy in nonblacks, but virtually all of the antihypertensive effect in blacks could be attributed to the amlodipine component. Among nonblack patients in placebo-controlled trials comparing amlodipine besylate and benazepril hydrochloride to the individual components, the blood pressure lowering effects of the combination were shown to be additive and in some cases synergistic.u00a0
  • During chronic therapy with amlodipine besylate and benazepril hydrochloride, the maximum reduction in blood pressure with any given dose is generally achieved after 1-2 weeks. The antihypertensive effects of amlodipine besylate and benazepril hydrochloride have continued during therapy for at least 1 year. Abrupt withdrawal of amlodipine besylate and benazepril hydrochloride has not been associated with a rapid increase in blood pressure.
  • Amlodipine besylate and benazepril hydrochloride is available as capsules containing amlodipine besylate equivalent to 5 mg of amlodipine, with 10 mg of benazepril hydrochloride providing for the following available combinations: 5 mg/10 mg,
  • Amlodipine besylate and benazepril hydrochloride capsules, 5 mg/10 mg contain white to off-white powder and size u201c4u201d hard gelatin capsules of ivory color cap and ivory color body, filled in size u201c1u201d hard gelatin capsule with yellow color cap and ivory color body, imprinted u201cRDYu201don cap and u201c339u201d on body with black ink and are supplied in bottles of 30, 60 and 90.u00a0
  • Bottles of 30u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0NDC 33261-0824-30
  • Bottles of 60u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0 NDC 33261-0824-60
  • Bottles of 90 u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0 NDC 33261-0824-90u00a0
  • Storage: Store at 20u00b0-25u00b0C (68u00b0-77u00b0F); [See USP Controlled Room Temperature.]Protect from moisture. Dispense in tight container (USP).u00a0
  • Female patients of childbearing age should be told about the consequences of exposure to amlodipine besylate and benazepril hydrochloride during pregnancy. Discuss treatment options with women planning to become pregnant. Patients should be asked to report pregnancies to their physicians as soon as possible.
  • Arrayn- Array
  • Read this Patient Information leaflet before you start taking amlodipine besylate and benazepril hydrochloride capsules and each time you get a refill. There may be new information. This leaflet does not replace talking with your doctor. If you have any questions, ask your doctor or pharmacist.
  • What is amlodipine besylate and benazepril hydrochloride capsules?
  • Amlodipine besylate and benazepril hydrochloride capsules contains two prescription medicines that work together to lower blood pressure: amlodipine besylate (the active ingredient found in Norvasc), a calcium channel blocker, and benazepril hydrochloride (Lotensinu00ae), an ACE inhibitor. Your doctor will prescribe amlodipine besylate and benazepril hydrochloride capsules only after other medicines havenu2019t worked.
  • High Blood Pressure (hypertension
  • Amlodipine besylate and benazepril hydrochloride capsules has not been studied in children.
  • Who should not take amlodipine besylate and benazepril hydrochloride capsules?
  • Donu2019t take amlodipine besylate and benazepril hydrochloride capsules if you are allergic to any of the ingredients.
  • What should I tell my Doctor before taking amlodipine besylate and benazepril hydrochloride capsules?
  • Tell your doctor about all your medical conditions, including if:
  • u2022u00a0u00a0u00a0u00a0u00a0 See n
  • u2022u00a0u00a0u00a0u00a0u00a0 Amlodipine besylate and benazepril hydrochloride capsules may pass into your milk. Donu2019t breastfeed while you are taking amlodipine besylate and benazepril hydrochloride capsules.
  • u2022u00a0u00a0u00a0u00a0u00a0 you have a heart condition
  • u2022u00a0u00a0u00a0u00a0u00a0 you have liver problems
  • u2022u00a0u00a0u00a0u00a0u00a0 you have kidney problems
  • u2022u00a0u00a0u00a0u00a0u00a0 you are about to have an operation (including dental surgery) or emergency treatment
  • u2022 u00a0u00a0u00a0u00a0u00a0you are suffering from several episodes of vomiting or diarrhea u00a0
  • u2022u00a0u00a0u00a0u00a0u00a0 you are treated for hyperkalemia (too much potassium in the blood)
  • u2022u00a0u00a0u00a0u00a0u00a0 you are taking already a diuretic (a medicine to increase the amount of urine you produce)
  • Keep a list of your medicines with you, including vitamins and natural or herbal remedies, to show your doctor or pharmacist. Some of your other medicines and amlodipine besylate and benazepril hydrochloride capsules could affect each other, causing serious side effects. Tell your doctor about all your medicines, especially:
  • u2022u00a0u00a0u00a0u00a0u00a0 Simvastatin, (a medicine used to control elevated cholesterol)
  • u2022u00a0u00a0u00a0u00a0u00a0 medicines for high blood pressure or heart failure
  • u2022u00a0u00a0u00a0u00a0u00a0 water pills, extra potassium or a salt substitute
  • u2022u00a0u00a0u00a0u00a0u00a0 Lithium (Eskalith, Lithobid)
  • u2022u00a0u00a0u00a0u00a0u00a0 potassium-containing medicines, potassium supplements or salt substitutes containing potassium;
  • u2022u00a0u00a0u00a0u00a0u00a0 cyclosporin, an immunosuppressant medicine used in transplanted patients to reduce the risk of organ rejection;
  • u2022u00a0u00a0u00a0u00a0u00a0 indomethacin and other non-steroidal anti-inflammatory agents, medicines used to relieve pain and inflammation;
  • u2022u00a0u00a0u00a0u00a0u00a0 insulin or oral antidiabetics, medicines that help a person with diabetes to control their level of glucose (sugar) in the blood;
  • u2022u00a0u00a0u00a0u00a0u00a0 gold for the treatment of rheumatoid arthritis;
  • u2022u00a0u00a0u00a0u00a0u00a0 probenecid, a medicine used to treat gout and hyperuricemia;
  • u2022u00a0u00a0u00a0u00a0u00a0 medicines used to prevent and treat fungal skin infections (e.g. ketoconazole, itraconazole)
  • u2022u00a0u00a0u00a0u00a0u00a0 medicines used to treat AIDS or HIV infections (e.g. ritonavir, indinavir)
  • u2022u00a0u00a0u00a0u00a0u00a0 medicines used to treat bacterial infections (e.g. clarithromycin)
  • Avoid alcohol until you have discussed the matter with your doctor. Alcohol may make blood pressure fall more and/or increase the possibility of dizziness or fainting.
  • How do I take amlodipine besylate and benazepril hydrochloride capsules?
  • u2022u00a0u00a0u00a0u00a0u00a0 Take amlodipine besylate and benazepril hydrochloride capsules exactly as your doctor tells you.
  • u2022u00a0u00a0u00a0u00a0u00a0 Take amlodipine besylate and benazepril hydrochloride capsules at the same time each day, with or without food.
  • u2022u00a0u00a0u00a0u00a0u00a0 If you miss a dose, take it as soon as you remember. If it is more than 12 hours, just take your next dose at the regular time.
  • u2022u00a0u00a0u00a0u00a0u00a0 Your doctor may test for kidney problems or check your blood potassium level.
  • u2022u00a0u00a0u00a0u00a0u00a0 If you take too much amlodipine besylate and benazepril hydrochloride capsules, call your doctor or Poison Control Center, or go to the emergency room.
  • u2022u00a0u00a0u00a0u00a0u00a0 Tell all your doctors or dentist you are taking amlodipine besylate and benazepril hydrochloride capsules if you:
  • u00a0u00a0u00a0u00a0u00a0 -u00a0u00a0u00a0u00a0u00a0 are going to have surgery
  • u00a0u00a0u00a0u00a0u00a0 -u00a0u00a0u00a0u00a0u00a0 are getting allergy shots for bee stings
  • u00a0u00a0u00a0u00a0u00a0 -u00a0u00a0u00a0u00a0u00a0 go for kidney dialysis
  • What are the possible side effects of amlodipine besylate and benazepril hydrochloride capsules?
  • Amlodipine besylate and benazepril hydrochloride capsules can cause serious side effects including:
  • u2022u00a0u00a0u00a0u00a0u00a0n
  • u00a0u00a0u00a0u00a0u00a0 Stop amlodipine besylate and benazepril hydrochloride capsules and get emergency help right away if you get:
  • u00a0u00a0u00a0u00a0u00a0 -u00a0u00a0u00a0u00a0u00a0 swelling of your face, eyelids, lips, tongue or throat
  • u00a0u00a0u00a0u00a0u00a0 -u00a0u00a0u00a0u00a0u00a0 have trouble swallowing
  • u00a0u00a0u00a0u00a0u00a0 -u00a0u00a0u00a0u00a0u00a0 asthma (wheezing) or other breathing problems
  • These allergic reactions are rare but happen more times in people who are African-American.
  • u2022u00a0u00a0u00a0u00a0u00a0 (hypotension). Low blood pressure is most likely to happen if you also take water pills, are on a low salt diet, get dialysis treatments, have heart problems or get sick with vomiting or diarrhea. Lie down if you feel faint or dizzy.
  • u2022u00a0u00a0u00a0u00a0u00a0 Call your doctor if:
  • u2022u00a0u00a0u00a0u00a0u00a0 you have nausea
  • u2022u00a0u00a0u00a0u00a0u00a0 you feel more tired or weaker than usual
  • u2022u00a0u00a0u00a0u00a0u00a0 you have itching
  • u2022u00a0u00a0u00a0u00a0u00a0 your skin or eyes look yellow
  • u2022u00a0u00a0u00a0u00a0u00a0 you have pain in your upper right stomach
  • u2022u00a0u00a0u00a0u00a0u00a0 you have flu-like symptoms
  • u2022u00a0u00a0u00a0u00a0u00a0 Some people will have changes on blood tests for kidney function and need a lower dose of amlodipine besylate and benazepril hydrochloride capsules. Call your doctor if you get swelling in your feet, ankles, or hands or unexplained weight gain.
  • u2022u00a0u00a0u00a0u00a0u00a0 in people that already have severe heart problems. Get emergency help if you get worse chest pain or chest pain that does not go away.
  • The more common side effects of amlodipine besylate and benazepril hydrochloride capsules are:
  • u2022u00a0u00a0u00a0u00a0u00a0 dizziness, fainting on standing up
  • u2022u00a0u00a0u00a0u00a0u00a0 cough (dry, non-productive, mainly at night, continuing)
  • u2022u00a0u00a0u00a0u00a0u00a0 swelling of the feet, ankles, and handsu00a0
  • If any of these affects you severely, tell your doctor.
  • These are not all the side effects of amlodipine besylate and benazepril hydrochloride capsules. For a complete list, ask your doctor or pharmacist.
  • How do I store amlodipine besylate and benazepril hydrochloride capsules?
  • u2022u00a0u00a0u00a0u00a0u00a0 Store amlodipine besylate and benazepril hydrochloride capsules at 20u00b0-25u00b0C (68u00b0-77u00b0F); [See USP Controlled Room Temperature.]
  • u2022u00a0u00a0u00a0u00a0u00a0 Keep amlodipine besylate and benazepril hydrochloride capsules in a closed container in a dry place.
  • u2022u00a0u00a0u00a0u00a0u00a0 Keep amlodipine besylate and benazepril hydrochloride capsules and all medicines out of the reach of children.
  • General Information about amlodipine besylate and benazepril hydrochloride capsules
  • Doctors can also use medicine for a condition that is not in the patient information leaflet. Take amlodipine besylate and benazepril hydrochloride capsules the way your doctor tells you. Do not share it with other people. It may harm them.
  • For more information, ask your doctor or pharmacist, or call 1-888-375-3784.
  • What are the ingredients in amlodipine besylate and benazepril hydrochloride capsules?
  • Active ingredients: amlodipine besylate, benazepril hydrochloride USP.u00a0
  • Inactive ingredients: colloidal silicon dioxide, crospovidone, hydrogenated castor oil, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, sodium starch glycolate and talc. Each hard-gelatin capsule contains gelatin, sodium lauryl sulfate, titanium dioxide, D&C yellow # 10 and D&C red # 28, (5 mg/20 mg, 10 mg/40 mg),u00a0 FD&C blue # 1 and FD&C red # 40 (5 mg/20 mg, 5 mg/40 mg),u00a0 FD & C Yellow 6 (5 mg/40 mg), FD&C green # 3 (2.5 mg/10 mg), iron oxide black (10 mg/20 mg) and iron oxide red (5 mg/20 mg and 10 mg/20 mg ) as coloring agents.
  • Norvasc is a registered trademark of Pfizer, Inc..
  • Lotensinis a registered trademark of Novartis Corp.
  • Eskalithu00a0and Lithobidare registered u00a0trademarks of Noven Therapeutics, LLC..
  • To reorder additional Patient Information Leaflets, please contact Dr. Reddyu2019s Customer Service at1-866-733-3952.
  • R Only
  • Manufactured by:
  • Dr. Reddyu2019s Laboratories Limited
  • Bachupally - 500 090u00a0 INDIAu00a0
  • Repackaged By :Aidarex Pharmaceuticals LLC,Corona, CA 92880
  • Revised: 1112
  • Containeru00a05 mg/10 mg:

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