Atropine And Pralidoxime Chloride - Auto-Injector (Atnaa Atropine And Pralidoxime Chloride)

Trade Name : ATNAA atropine and pralidoxime chloride

Meridian Medical Technologies, Inc.

KIT

Strength

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Atropine And Pralidoxime Chloride - Auto-Injector (Atnaa Atropine And Pralidoxime Chloride) which is also known as ATNAA atropine and pralidoxime chloride and Manufactured by Meridian Medical Technologies, Inc.. It is available in strength of per ml. Read more

Atropine And Pralidoxime Chloride - Auto-Injector (Atnaa Atropine And Pralidoxime Chloride) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

Read more
  • No data
  • The Antidote Treatment - Nerve Agent, Auto-Injector (ATNAA) provides Atropine Injection and Pralidoxime Chloride Injection in separate chambers as sterile, pyrogen-free solutions for intramuscular injection.n
  • The ATNAA is a specially designed unit for automatic self- or buddy-administration by military personnel. When activated, the ATNAA sequentially administers atropine and pralidoxime chloride through a single needle. The recommended procedure (see ) is to inject the contents of the auto-injector into the muscles of an outer thigh or into the buttocks.n
  • When activated, each ATNAA dispenses:n
  • 2.1 mg atropine in 0.7 mL of a sterile, pyrogen-free solution containing 12.47 mg glycerin and not more than 2.8 mg phenol, citrate buffer, and Water for Injection. The pH range is 4.0 u2013 5.0.n
  • Andn
  • 600 mg of pralidoxime chloride in 2 mL of a sterile, pyrogen-free solution containing 40 mg benzyl alcohol, 22.5 mg glycine, and Water for Injection. The pH is adjusted with hydrochloric acid. The pH range is 2.0 u2013 3.0.n
  • After an ATNAA has been activated, the empty container should be disposed of properly (seen
  • Arrayn- DOSAGE AND ADMINISTRATION
  • Atropine, an anticholinergic agent (muscarinic antagonist), occurs as white crystals, usually needle- like, or as a white, crystalline powder. It is slightly soluble in water, soluble in glycerin and ether, and freely soluble in alcohol and chloroform with a molecular weight of 289.38. Atropine, a naturally occurring belladonna alkaloid, is a racemic mixture of equal parts of d- and l- hyoscyamine, whose activity is due almost entirely to the levo isomer of the drug. Chemically, atropine is designated as 1u03b1H,5u03b1H-Tropan-3u03b1-ol (u00b1)-tropate. Its empirical formula is CHNO and its structural formula is:n
  • Pralidoxime chloride, a cholinesterase reactivator, is an odorless, white to pale-yellow crystalline powder, freely soluble in water, with a molecular weight of 172.61. Chemically, pralidoxime chloride is designated as 2-formyl-1-methylpyridinium chloride oxime. Its empirical formula is CHCINO and its structural formula is:n
  • The specific activity of the drug resides in the 2-formyl-1-methylpyridinium ion and is independent of the particular salt employed. The chloride salt is preferred because of physiologic compatibility, excellent water solubility at all temperatures, and high potency per gram, due to its low molecular weight.n
  • No data
  • The ATNAA is indicated for the treatment of poisoning by susceptible organophosphorous nerve agents having anticholinesterase activity.n
  • In the face of life-threatening poisoning by organophosphorous nerve agents, there are no absolute contraindications for the use of the ATNAA (see ).n
  • While ATNAA can be administered to all individuals with a life-threatening exposure to organophosphorous nerve agents, it should be administered with extreme caution to individuals with the following disorders when the symptoms of nerve agent poisoning are less severe: individuals who are hypersensitive to any component of the product, disorders of heart rhythm such as atrial flutter, severe narrow angle glaucoma, pyloric stenosis, or prostatic hypertrophy.n
  • More than one dose of ATNAA, to a maximum of three doses, may be necessary, especially when exposure is massive or symptoms are severe (see ). Children are more susceptible than adults to the toxic effects of anticholinergic agents.n
  • Severe difficulty in breathing requires artificial respiration in addition to the use of the ATNAA.n
  • Pralidoxime is not effective in the treatment of poisoning due to phosphorus, inorganic phosphates, or organophosphates not having anticholinesterase activity.n
  • No data
  • Mild to moderate pain may be experienced at the site of injection.n
  • Atropine and pralidoxime chloride are not subject to abuse and possess no known potential for dependence.n
  • No data
  • For optimal reactivation of organophosphorous-inhibited cholinesterase, the ATNAA should be administered as soon as possible after appearance of symptoms of nerve agent poisoning (see below).n
  • The ATNAA should be self- or buddyu2013administered by military personnel after donning protective mask and hood at the first sign of a chemical attack, and only if some or all of the following mild symptoms of nerve agent exposure are present:n
  • The following are the instructions that should be given to military personnel.n
  • The Antidote Treatment u2013 Nerve Agent, Auto-Injector (ATNAA) provides Atropine Injection (atropine, 2.1 mg/0.7 mL) and Pralidoxime Chloride Injection (pralidoxime chloride, 600 mg/2 mL) in sterile solutions for intramuscular injection. The ATNAA is a self-contained unit designed for automatic self- or buddy-administration by military personnel. ATNAAs are supplied through the Directorate of Medical Materiel, Defense Supply Center, Philadelphia.n
  • Store at 25u00b0C (77u00b0F); excursions permitted to 15 - 30u00b0C (59 - 86u00b0F)
  • [see USP Controlled Room Temperature]n
  • Keep from Freezing. Protect from Light.
  • Manufactured by:n
  • MERIDIAN MEDICAL TECHNOLOGIES, INC.A wholly-owned subsidiary of King Pharmaceuticals, Inc.n
  • 00015664/10n
  • Rx only.n
  • ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------n
  • No data
  • Principal Display Paneln
  • ANTIDOTE TREATMENT NERVE AGENT, AUTO-INJECTOR
  • For Use in Nerve Agent Poisoning Onlyn
  • ATROPINE INJECTION 2.1 MG,n
  • PRALIDOXIME CHLORIDE INJECTION 600MGn
  • MERIDIAN MEDICAL TECHNOLOGIESn- Array
  • Columbia, MD 21046, USAn
  • A Pfizer Company.n
  • ATNAA Utilizes Binajectn- Arrayn- Technology 0001860
  • Sterile Solution for Intramuscular Use Only
  • NSN 6505-01-362-7427n
  • NDC 11704-777-01n
  • Rx Onlyn
  • Store at 25u00b0C (77u00b0F); excursions permitted to 15 - 30u00b0C (59-86u00b0F).n
  • Keep From Freezing. Protect From Light.n

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