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Atropine Sulfate (Atropine Sulfate)

Trade Name : Atropine Sulfate

Hospira, Inc.

INJECTION, SOLUTION

Strength 0.1 mg/mL

ATROPINE SULFATE Anticholinergic [EPC],Cholinergic Antagonists [MoA],Cholinergic Muscarinic Antagonist [EPC],Cholinergic Muscarinic Antagonists [MoA]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Atropine Sulfate (Atropine Sulfate) which is also known as Atropine Sulfate and Manufactured by Hospira, Inc.. It is available in strength of 0.1 mg/mL per ml. Read more

Atropine Sulfate (Atropine Sulfate) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Atropine Sulfate Injection, USP, is indicated for temporary blockade of severe or life threatening muscarinic effects, e.g., as an antisialagogue, an antivagal agent, an antidote for organophosphorus or muscarinic mushroom poisoning, and to treat bradyasystolic cardiac arrest.
  • Atropine is a muscarinic antagonist indicated for temporary blockade of severe or life threatening muscarinic effects. ()
  • No data
  • 2.1n- 2.3
  • Arrayn- Array
  • Injection: 0.05 mg/mL and 0.1 mg/mL in Ansyru2122 Plastic Syringes containing a clear, colorless solution in a polypropylene syringe.
  • Each Ansyru2122 5 mL Plastic Syringe contains 0.25 mg of atropine sulfate (0.05 mg/mL concentration).
  • Each Ansyru2122 10 mL Plastic Syringe contains 1 mg of atropine sulfate (0.1 mg/mL concentration).
  • None.
  • None. ()
  • Tachycardia ()Glaucoma ()Pyloric obstruction ()Worsening urinary retention ()Viscid bronchial plugs ()
  • The following adverse reactions have been identified during post-approval use of atropine sulfate. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
  • Most of the side effects of atropine are directly related to its antimuscarinic action. Dryness of the mouth, blurred vision, photophobia and tachycardia commonly occur. Anhidrosis can produce heat intolerance. Constipation and difficulty in micturition may occur in elderly patients. Occasional hypersensitivity reactions have been observed, especially skin rashes which in some instances progressed to exfoliation.
  • Most adverse reactions are directly related to atropine's antimuscarinic action. Dryness of the mouth, blurred vision, photophobia and tachycardia commonly occur with chronic administration of therapeutic doses. ()
  • Atropine Sulfate Injection decreased the rate of mexiletine absorption without altering the relative oral bioavailability; this delay in mexiletine absorption was reversed by the combination of atropine and intravenous metoclopramide during pretreatment for anesthesia.
  • Mexiletine:
  • 7.1
  • No data
  • Excessive dosing may cause palpitation, dilated pupils, difficulty in swallowing, hot dry skin, thirst, dizziness, restlessness, tremor, fatigue and ataxia. Toxic doses lead to restlessness and excitement, hallucinations, delirium and coma. Depression and circulatory collapse occur only with severe intoxication. In such cases, blood pressure declines and death due to respiratory failure may ensue following paralysis and coma.
  • The fatal adult dose of atropine is not known. In pediatric populations, 10 mg or less may be fatal.
  • In the event of toxic overdosage, a short acting barbiturate or diazepam may be given as needed to control marked excitement and convulsions. Large doses for sedation should be avoided because central depressant action may coincide with the depression occurring late in atropine poisoning. Central stimulants are not recommended.
  • Physostigmine, given as an atropine antidote by slow intravenous injection of 1 to 4 mg (0.5 to 1 mg in pediatric populations), rapidly abolishes delirium and coma caused by large doses of atropine. Since physostigmine is rapidly destroyed, the patient may again lapse into coma after one to two hours, and repeated doses may be required.
  • Artificial respiration with oxygen may be necessary. Ice bags and alcohol sponges help to reduce fever, especially in pediatric populations.
  • Atropine is not removed by dialysis.
  • Atropine Sulfate Injection, USP is a sterile, nonpyrogenic isotonic solution of atropine sulfate monohydrate in water for injection with sodium chloride sufficient to render the solution isotonic. It is administered parenterally by subcutaneous, intramuscular or intravenous injection.
  • Each milliliter (mL) contains 0.1 mg (adult strength) or 0.05 mg (pediatric strength) of atropine sulfate monohydrate equivalent to 0.083 mg (adult strength) or 0.042 mg (pediatric strength) of atropine, and sodium chloride, 9 mg. May contain sodium hydroxide and/or sulfuric acid for pH adjustment 0.308u00a0mOsmol/mL (calc.). pH (3.0 to 6.5).
  • Sodium chloride added to render the solution isotonic for injection of the active ingredient is present in amounts insufficient to affect serum electrolyte balance of sodium (Na) and chloride (Cl) ions.
  • The solution contains no bacteriostat, antimicrobial agent or added buffer (except for pH adjustment) and is intended for use only as a single-dose injection. When smaller doses are required the unused portion should be discarded.
  • Atropine Sulfate, USP is chemically designated 1u03b1 H, 5u03b1 H-Tropan-3-u03b1-ol (u00b1)-tropate (ester), sulfate (2:1) (salt) monohydrate, (CHNO) u2219 HSO u2219 HO, colorless crystals or white crystalline powder very soluble in water. It has the following structural formula:
  • Atropine, a naturally occurring belladonna alkaloid, is a racemic mixture of equal parts of d- and 1-hyocyamine, whose activity is due almost entirely to the levo isomer of the drug.
  • Sodium Chloride, USP is chemically designated NaCl, a white crystalline powder freely soluble in water.
  • The syringe is molded from a specially formulated polypropylene. Water permeates from inside the container at an extremely slow rate which will have an insignificant effect on solution concentration over the expected shelf life. Solutions in contact with the plastic container may leach out certain chemical components from the plastic in very small amounts; however, biological testing was supportive of the safety of the syringe material.
  • No data
  • Studies have not been performed to evaluate the carcinogenic or mutagenic potential of atropine or its potential to affect fertility adversely.
  • Atropine Sulfate Injection, USP is supplied in single-dose syringes as follows:
  • Store at 20u00b0C to 25u00b0C (68u00b0F to 77u00b0F); excursions permitted between 15u00b0C and 30u00b0C (59u00b0F and 86u00b0F). [See USP Controlled Room Temperature.]
  • Distributed by Hospira, Inc., Lake Forest, IL 60045 USA u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0n
  • LAB-1041-3.0
  • Atropine Sulfate 1 mg/10 mL
  • 10 mL Single-Dose Syringe
  • NDC 0409-1630-15Rx only
  • Atropine Sulfaten- 1 mg/10 mL
  • Hospira
  • For Intravenous, Intramuscular, Subcutaneous or Endotracheal use.
  • Distributed by Hospira, Inc., Lake Forest, IL 60045 USA
  • RL-7088
  • NDC 0409-1630-15Rx only
  • 10 mL
  • AtropineSulfate
  • 1 mg/10 mL
  • For Intravenous,Intramuscular,Subcutaneous orEndotracheal Use
  • Ansyr
  • Single-Dose Syringe
  • Hospira
  • u25c0 PRESS AND PULL TO OPEN u25b6
  • Atropine Sulfate 0.25 mg/5 mL
  • 5 mL Single-Dose SyringeRx onlyNDC 0409-9630-15
  • PEDIATRIC 0.25 mg/5 mLn- Atropine Sulfate
  • Hospira
  • For Intravenous, Intramuscular, Subcutaneous or Endotracheal Use.
  • Dist. by Hospira, Inc., Lake Forest, IL 60045 USA
  • RL-7089
  • NDC 0409-9630-15 Rx only
  • 5 mL
  • Pediatric Atropine Sulfate
  • 0.25 mg/5 mL
  • For Intravenous, Intramuscular, Subcutaneous or Endotracheal Use
  • Ansyr
  • Single-Dose Syringe
  • Hospira
  • u25c0 PRESS AND PULL TO OPEN u25b6

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