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Betamethasone Dipropionate (Betamethasone Dipropionate)

Trade Name : Betamethasone Dipropionate

E. Fougera & Co. a division of Fougera Pharmaceuticals Inc.

CREAM

Strength 0.5 mg/g

BETAMETHASONE DIPROPIONATE Corticosteroid [EPC],Corticosteroid Hormone Receptor Agonists [MoA]

Delivery Process

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Product information is meant for

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Betamethasone Dipropionate (Betamethasone Dipropionate) which is also known as Betamethasone Dipropionate and Manufactured by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc.. It is available in strength of 0.5 mg/g per ml. Read more

Betamethasone Dipropionate (Betamethasone Dipropionate) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • (Potency expressed as betamethasone)
  • Rx only
  • FOR DERMATOLOGIC USE ONLY.NOTu00a0FOR OPHTHALMIC USE.
  • Betamethasone Dipropionate Cream, Ointment and Lotion contain betamethasone dipropionate USP, a synthetic adrenocorticosteroid, for dermatologic use. Betamethasone, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.
  • Betamethasone dipropionate is a white to cream white odorless crystalline powder insoluble in water. Chemically, it is 9-fluoro-11u03b2,17,21-trihydroxy-16u03b2-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate. The structural formula is:
  • Each gram of the 0.05% Cream contains 0.64 mg betamethasone dipropionate (equivalent to 0.5 mg betamethasone) in a soft, white, hydrophilic cream of purified water, mineral oil, white petrolatum, polyethylene glycol 1000 monocetyl ether, cetostearyl alcohol, monobasic sodium phosphate (monohydrate);u00a0chlorocresolu00a0is present as a preservative. Sodium hydroxide or phosphoric acid solution to adjust pH, if required.
  • Each gram of the 0.05% Ointment contains 0.64 mg betamethasone dipropionate (equivalent to 0.5 mg betamethasone) in an ointment base of mineral oil and white petrolatum.
  • Each gram of the 0.05% Lotion contains 0.64 mg betamethasone dipropionate (equivalent to 0.5 mg betamethasone) in a vehicle of isopropyl alcohol and purified water slightly thickened with carbomer 934P.u00a0Sodium hydroxide solutionu00a0to adjust pH, if required.
  • Topical corticosteroids share anti-inflammatory, anti-pruritic and vasoconstrictive actions.
  • The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man.
  • Pharmacokinetics:
  • Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids (See ).
  • Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.
  • Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
  • Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
  • No data
  • The following local adverse reactions are reported infrequently when Betamethasone Dipropionate products are used as recommended in the section. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infections, skin atrophy, striae and miliaria.
  • Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia and glucosuria in some patients.
  • Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects (See ).
  • Apply a thin film of Betamethasone Dipropionate Cream or Ointment to the affected skin areas once daily. In some cases, twice daily dosage may be necessary.
  • Apply a few drops of Betamethasone Dipropionate Lotion to the affected skin areas and massage lightly until it disappears. Apply twice daily, in the morning and at night.
  • If an infection develops, appropriate antimicrobial therapy should be instituted.
  • Betamethasone Dipropionate products should not be used with occlusive dressings.
  • Store at 25u00b0C, excursions permitted between 15u00b0 and 30u00b0C. Protect from light and freezing.
  • E. FOUGERA & CO.A division offougeraPHARMACETICALS INC.Melville, New York 11747
  • I255JR07/12#74
  • NDC
  • FOUGERA
  • BETAMETHASONE n- DIPROPIONATE n- CREAM USP, 0.05% n- (Potency expressed as betamethasone)
  • Rx only
  • NET WT 45 grams
  • NDC
  • FOUGERA
  • BETAMETHASONE DIPROPIONATE n- CREAM USP, 0.05% n- (Potency expressed as betamethasone)
  • Rx only
  • NET WT 45 grams
  • NDC
  • FOUGERA
  • Rx only
  • NET WT 15 grams
  • NDC
  • FOUGERA
  • BETAMETHASONE DIPROPIONATE n- OINTMENT USP, 0.05% n- (Potency expressed as betamethasone)
  • Rx only
  • NET WT 15 grams
  • NDC
  • FOUGERA
  • BETAMETHASONE n- DIPROPIONATE n- LOTION USP, 0.05% n- (Potency expressed as betamethasone)
  • 60 mL
  • Rx only
  • NDC
  • FOUGERA
  • BETAMETHASONE n- DIPROPIONATE n- LOTION USP, 0.05% n- (Potency expressed as n- betamethasone)
  • 60 mL
  • Rx only

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