“We use cookies on this website to enhance your user experience and to personalise content. By clicking any link or continuing to use our Website you agree to our cookies as per our Privacy Policy. Read More” Ok, I agree

Carmustine (Carmustine)

Trade Name : carmustine

Amneal Biosciences LLC

KIT

Strength

Delivery Process

Submit a Request

You can fill in a request for your medicine through the form provided. You can access the form by clicking on the ‘Get Price’ button.

We’ll Get in Touch

Once we review your request, we’ll send you an estimated price for the medicine within 2-5 days.

Confirmation and Payment

You can fill in a request for your medicine through the form provided. You can access the form by clicking on the ‘Get Price’ button.

Submit a Request

You can fill in a request for your medicine through the form provided. You can access the form by clicking on the ‘Get Price’ button.

Product information is meant for

Wholesalers Suppliers Exporters Doctors MOH Tender Supplies Hospitals Brand CROs Comparator Supplies Generic Cooperate Sourcing Individual Patients Indian Institutional Buyers

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Carmustine (Carmustine) which is also known as carmustine and Manufactured by Amneal Biosciences LLC. It is available in strength of per ml. Read more

Carmustine (Carmustine) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

Inquire directly from our website and get 5% off on any medicine!

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

Read more

About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

Read more
  • No data
  • Myelosuppression
  • Carmustine for injection causes suppression of marrow function (including thrombocytopenia and leukopenia), which may contribute to bleeding and overwhelming infections and. Monitor blood counts weekly for at least 6 weeks after each dose. Adjust dosage based on nadir blood counts from the prior dose . Do not administer a repeat course of carmustine for injection until blood counts recover.
  • Pulmonary Toxicity
  • Cn- armustine for injection causes dose-related pulmonary toxicity. Patients receiving greater than 1,400 mg/mcumulative dose are at significantly higher risk than those receiving less. Delayed pulmonary toxicity can occur years after treatment, and can result in death, particularly in patients treated in childhood and .
  • WARNING: MYELOSUPPRESSION and PULMONARY TOXICITY
  • See full prescribing information for complete boxed warning
  • Carmustine for injection is indicated as palliative therapy as a single agent or in established combination therapy in the following:
  • -u00a0u00a0u00a0 Brain tumors glioblastoma, brainstem glioma, medulloblastoma, astrocytoma, ependymoma, and metastatic brain tumors.
  • -u00a0u00a0u00a0 Multiple myeloma in combination with prednisone.
  • -u00a0u00a0u00a0 Relapsed or refractory Hodgkin's lymphoma in combination with other approved drugs.
  • -u00a0u00a0u00a0 Relapsed or refractory Non-Hodgkin's lymphomas in combination with other approved drugs.
  • Carmustine for injection is a nitrosourea indicated as palliative therapy as a single agent or in established combination therapy with other approved chemotherapeutic agents in the following:
  • Brain tumors glioblastoma, brainstem glioma, medulloblastoma, astrocytoma, ependymoma, and metastatic brain tumors. ()
  • Multiple myeloma-in combination with prednisone. ()
  • Relapsed or refractory Hodgkin's lymphoma in combination with other approved drugs. ()
  • Relapsed or refractory Non-Hodgkin's lymphomas in combination with other approved drugs. ()
  • No data
  • Recommended Dosage: As a single agent, 150 mg/m to 200 mg/m carmustine for injection intravenously every 6 weeks as a single-dose or divided into daily injections such as 75 mg/m to 100 mg/m on 2 successive days. Adjust dose for combination therapy or in patients with reduced bone marrow reserve. ()
  • Administer reconstituted solution only as a slow intravenous infusion over at least 2 hours. ()
  • Carmustine for Injection, USP is a lyophilized pale yellow flakes or congealed mass containing carmustine, USP in an amber colored glass vial for single-dose use. It is supplied with 3 mL of dehydrated alcohol injection, USP (sterile diluent for carmustine for injection) for reconstitution.
  • For injection: 100 mg of carmustine lyophilized powder in a single-dose vial for reconstitution and a vial containing 3mL sterile diluent (Dehydrated Alcohol Injection, USP). ()n n
  • Carmustine for injection is contraindicated in patients with previous hypersensitivity to carmustine for injection or its components.
  • Hypersensitivity. ()
  • No data
  • Administration Reactions: Extravasation may occur; monitor infusion site closely during administration. ()
  • Carcinogenicity: Potentially carcinogenic to humans. Monitor patient periodically for such signs and apprise the patient of the symptoms for which they need to seek medical help. ()
  • Ocular Toxicity: Has occurred when administered via unapproved intraarterial intracarotid route. ()
  • Embryo-Fetal toxicity: Can cause fetal harm. Advise females of reproductive potential of the potential risk to a fetus and to avoid pregnancy. ()
  • The following serious adverse reactions are described elsewhere in the labeling:
  • The following adverse reactions associated with the use of carmustine for injection were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
  • Arrayn- Cardiac Disorders
  • Tachycardia and chest pain
  • Arrayn- Eye Disorders
  • Conjunctival edema, conjunctival hemorrhage, blurred vision and loss of depth perception
  • Arrayn- Gastrointestinal Toxicity
  • Nausea, vomiting, anorexia, and diarrhea
  • Arrayn- Hepatotoxicity
  • Increased transaminase, increased alkaline phosphatase, increased bilirubin levels
  • Arrayn- Infections and Infestations
  • Opportunistic infection (including with fatal outcome)
  • Arrayn- Neoplasms Benign, Malignant and Unspecified (including cysts and polyps)
  • Acute leukemia, bone marrow dysplasias
  • Arrayn- Nephrotoxicity
  • Progressive azotemia, decrease in kidney size, renal failure
  • Arrayn- Nervous System Disorders
  • Headaches, encephalopathy, and seizures
  • Arrayn- Pulmonary Toxicity
  • Pneumonitis, interstitial lung disease
  • Arrayn- Reproductive System and Breast Disorders
  • Gynecomastia
  • Arrayn- Skin and Subcutaneous Tissue Disorders
  • Burning sensation, hyperpigmentation, swelling, pain, erythema, skin necrosis, alopecia, allergic reaction
  • Arrayn- Vascular Disorders
  • Veno-occlusive disease
  • Most common adverse reactions (> 1%) are nausea, vomiting, renal toxicity, pneumonitis, pulmonary toxicity, myelosuppression. ()
  • No data
  • Cimetidine: Increased myelosuppression with concomitant use. ()
  • Phenobarbital: Induces carmustine metabolism, reducing exposure. May lead to reduced efficacy. ()
  • Phenytoin: Carmustine for injection may reduce the efficacy of phenytoin. ()
  • No data
  • Lactation: Advise lactating females not to breastfeed. ()
  • The main result of overdose is myeloablation. No proven antidotes have been established for carmustine for injection overdosage.
  • The active ingredient in carmustine for injection, USP is a nitrosourea with the chemical name 1,3-bis(2-chloroethyl)-1-nitrosourea and a molecular weight of 214.05 g/mol. The drug product is supplied as sterile lyophilized pale yellow flakes or a congealed mass, and it is highly soluble in alcohol and lipids, and poorly soluble in water. Carmustine for injection is administered by intravenous infusion after reconstitution, as recommended.
  • The molecular formula of carmustine is CHClNO and the structural formula of carmustine is:
  • Carmustine for injection, USP is available in 100 mg single-dose vials of lyophilized material. Sterile diluent for constitution of carmustine for injection, USP is co-packaged with the active drug product for use in constitution of the lyophile. The diluent is supplied in a vial containing 3 mL of dehydrated alcohol injection, USP.
  • No data
  • Carmustine is carcinogenic in rats and mice, producing a marked increase in tumor incidence in doses approximating those employed clinically. Nitrosourea therapy does have carcinogenic potential in humans .
  • Carmustine was mutagenic and clastogenic in multiple and genetic toxicology studies.
  • Male rats treated with carmustine at cumulative doses u2265 36 mg/kg (216 mg/m), approximately 0.15 times the maximum cumulative human dose on a mg/mbasis, showed decreases in reproductive potential when mated with untreated female rats (e.g., decreased implantations, increased resorption rate, and a decrease in viable fetuses).
  • 1. u201cOSHA Hazardous Drugs.u201d . n
  • No data
  • Arrayn- Arrayn- see ]
  • A serious and frequent toxicity of carmustineu00a0 for injection is delayed myelosuppression and usually occurs 4 to 6 weeks after drug administration. Hence, patients should be advised to get blood counts monitored weekly for at least 6 weeks. The bone marrow toxicity of carmustine for injection is cumulative.
  • Arrayn- [see ]
  • Advise patients to contact a health care professional immediately for any of the following: shortness of breath, particularly during exercise, dry, hacking cough, fast, shallow breathing, gradual unintended weight loss, tiredness, aching joints and muscles, clubbing (widening and rounding) of the tips of the fingers or toes.
  • Arrayn- Arrayn- see ]
  • Inform the patient that they may suffer from fits and advise them to get medical attention immediately in such cases.
  • Arrayn- Arrayn- see n n- Arrayn- Array
  • Advise pregnant women and females of reproductive potential that carmustine for injection exposure during pregnancy can result in fetal harm. Advise female patients to contact their healthcare provider with a known or suspected pregnancy. Advise women of reproductive potential to avoid becoming pregnant. Advise females of reproductive potential to use effective contraception during treatment.
  • Arrayn- Arrayn- see ]
  • Advise the female patient to discontinue nursing while taking carmustine for injection.
  • Manufactured by:n Telangana 509301, INDIA
  • Distributed by:n Bridgewater, NJ 08807
  • Rev. 10-2018-01
  • Carmustine n- for Injection, USP
  • Arrayn- Array
  • About Combi Kit Guard.
  • -u00a0u00a0u00a0u00a0 This Combi Kit Guard is specially designed for your safety.
  • -u00a0u00a0u00a0u00a0 Please do not remove the vials from the Combi Kit Guard.
  • -u00a0u00a0u00a0u00a0 Keep the Combi Kit Guard in a carton till the time of use.
  • How to use this Combi Kit Guard
  • The instructions below explain how to use this Combi Kit Guard.
  • The Combi Kit Guard has two compartments. One holds the 100 mg carmustine vial and the other holds the 3 mL sterile diluent (Dehydrated Alcohol Injection, USP) vial.
  • List of items required: gloves, alcohol swabs, sterile syringe.
  • Wear gloves at all times when handling COMBI KIT Guard.
  • Discard the COMBI KIT Guard after use.
  • Please refer the product information leaflet before administration.
  • For more information, go to www.amneal.com or call toll-free 1-855-266-3251.
  • u00a0
  • Manufactured by:n Telangana 509301, INDIA
  • Distributed by:n Bridgewater, NJ 08807
  • Rev. 10-2018-01
  • NDC 70121-1668-1
  • Carmustine for Injection USP, 100 mg/vial
  • Rx Only
  • Vial Label
  • Amneal Biosciences LLC
  • NDC 70121-3639-1
  • Sterile Diluent (Dehydrated Alcohol Injection, USP), 3 mLn
  • Rx Only
  • Vial Label
  • Amneal Biosciences LLC
  • Arrayn- Array
  • NDC 70121-1482-2
  • Carmustine for Injection USP, 100 mg/vial
  • Rx Only
  • Carton Label
  • Amneal Biosciences LLC
  • Arrayn- Array
  • Arrayn- Array

Similar Products

Desogestrel And Ethinyl Estradiol (Emoquette)

Desogestrel And Ethinyl Estradiol (Emoquette)

Manufacturer: REMEDYREPACK INC.

Presentation: KIT

Strength:

Pack Size:

Diphenoxylate Hydrochloride And Atropine Sulfate (Diphenoxylate Hydrochloride And Atropine Sulfate)

Diphenoxylate Hydrochloride And Atropine Sulfate (Diphenoxylate Hydrochloride And Atropine Sulfate)

Manufacturer: REMEDYREPACK INC.

Presentation: TABLET

Strength: 2.5; .025 mg/1; mg/1

Pack Size:

Fluoxetine Hydrochloride (Fluoxetine)

Fluoxetine Hydrochloride (Fluoxetine)

Manufacturer: REMEDYREPACK INC.

Presentation: CAPSULE

Strength: 40 mg/1

Pack Size:

Metoprolol Succinate (Metoprolol Succinate)

Metoprolol Succinate (Metoprolol Succinate)

Manufacturer: REMEDYREPACK INC.

Presentation: TABLET, EXTENDED RELEASE

Strength: 25 mg/1

Pack Size:

Losartan Potassium (Losartan Potassium)

Losartan Potassium (Losartan Potassium)

Manufacturer: REMEDYREPACK INC.

Presentation: TABLET, FILM COATED

Strength: 25 mg/1

Pack Size:

Browse Our Services And Processes

Comparator Sourcing for Clinical Trials

Comparator Sourcing for Clinical Trials

GNH India brings over 10 years of experience in Comparator

Read More

Name Patient Supply

Name Patient Supply

Today, the exact cause for many rare diseases remains unknown

Read More

Validated Cold Chain Shipment

Validated Cold Chain Shipment

With shifting of pharma industry from synthetic molecules to biologic

Read More

Clinical Trials Supply

Clinical Trials Supply

STOP SOURCING..... START SMART SOURCING...... COME STRAIGHT TO THE SOURCE

Read More

Pharmaceutical Contract Manufacturing

Pharmaceutical Contract Manufacturing

GNH Provides Contract Manufacturing services for: Generic Medicines with following

Read More

Pricing

Pricing

PRICING POLICY Terms of sales are typically prepaid, unless otherwise

Read More

Disclaimer

Please see the Legal Notice for detailed terms and disclaimers. The Legal Notice governs the use of this Website and by accessing and using this Website you agree to be bound by and accept the Legal Notice.

Browse from other international pharmaceuticals

General

64020 Products

GNH India Brings to over 64036 Product SKUs from India all at 1 place with easy access and global deliveries.

US NDC

71245 Products

GNH India Brings to over 71252 Product SKUs from India all at 1 place with easy access and global deliveries.

Canadian DIN

51046 Products

GNH India Brings to over 51047 Product SKUs from India all at 1 place with easy access and global deliveries.

Swiss Drugs

150 Products

GNH India Brings to over 150 Product SKUs from India all at 1 place with easy access and global deliveries.

NZ Drugs

13296 Products

GNH Brings to over 13298 Product SKUs from India all at 1 place with easy access and global deliveries.

FAQ

Check out our delivery process

Can’t find what
you’re looking for?

Contact US
Get Price

Are you an existing customer or a vendor of GNH India? Log in here to

View your Transaction
COMPANY
SERVICES
QUICK LINKS
CONTACT US
Registered Office Address:

Unit # G- 14, 15, 16, 17, Ground Floor, Prabhadevi Industrial Estate, Enterprises Industrial Premises, 408, Veer Sawarkar Road, Prabhadevi,
Mumbai 400025 India

US Office Address:

GNH Pharmaceuticals USA LLC,
Suite E # 499, 1235 EAST BLVD,
Charlotte, NC, 28203, U.S.A
TEL: +1 704 557 0412

Pharmexcil
DB
FIEO-2016
SiteLock

Copyright © 2024 GNHIndia .com. All Rights Reserved. Please read Legal Notice for further details.

Disclaimer: Product names, logos, brands and other trademarks featured or referred to are the property of their respective trademark holders.