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Cephalexin (Cephalexin)

Trade Name : cephalexin

NuCare Pharmaceuticals, Inc.

CAPSULE

Strength 500 mg/1

CEPHALEXIN Cephalosporin Antibacterial [EPC],Cephalosporins [CS]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Cephalexin (Cephalexin) which is also known as cephalexin and Manufactured by NuCare Pharmaceuticals, Inc.. It is available in strength of 500 mg/1 per ml. Read more

Cephalexin (Cephalexin) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Cephalexin capsules USP is a semisynthetic cephalosporin antibiotic intended for oral administration.u00a0 It is 7-(D-u03b1-Amino-u03b1-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid monohydrate. Cephalexin has the molecular formula Cn n n Hn n n Nn n n On n n Su2022Hn n n O and the molecular weight is 365.41.u00a0n nn
  • Cephalexin has the following structural formula:
  • The nucleus of cephalexin is related to that of other cephalosporin antibiotics. The compound is a zwitterion; i.e., the molecule contains both a basic and an acidic group. The isoelectric point of cephalexin in water is approximately 4.5 to 5.u00a0
  • The crystalline form of cephalexin which is available is a monohydrate. It is a white crystalline solid having a bitter taste.u00a0 Solubility in water is low at room temperature; 1 or 2 mg/mL may be dissolved readily, but higher concentrations are obtained with increasing difficulty.
  • The cephalosporins differ from penicillins in the structure of the bicyclic ring system. Cephalexin has a Dn n n phenylglycyl group as substituent at the 7-amino position and an unsubstituted methyl group at the 3-position.n nn
  • Each capsule contains cephalexin monohydrate equivalent to 250 mg or 500 mg of cephalexin. The capsules also contain then n n following inactive ingredients: croscarmellose sodium, D&C Yellow No. 10, FD&C Blue No.1, FD&C Yellow No. 6, gelatin, magnesium stearate, microcrystalline cellulose, titanium dioxide. Ink constituents are: black iron oxide, butyl alcohol, dehydrated alcohol, isopropyl alcohol, potassium hydroxide, propylene glycol, shellac and strong ammonia solution.n nn
  • No data
  • Cephalexin capsules USP are indicated for the treatment of the following infections when caused by susceptibile strains of the designated microorganisms:
  • Respiratory tract infections caused by n n n and n n n (Penicillin is the usual drug of choice in the treatment and prevention of streptococcal infections, including the prophylaxis of rheumatic fever. Cephalexin is generally effective in the eradication of streptococci from the nasopharynx; however, substantial data estabilishing the efficacy of cephalexin in the subsequent prevention of rheumatic fever are not available at present.)n nn
  • Otitis media due to n n n , n n n n
  • Skin and skin structure infections caused by n n n and/or n n n n
  • Bone infections caused by n n n and/or n n n n
  • Genitourinary tract infections, including acute prostatitis, caused by n n n and n n n n
  • Note
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of cephalexin capsules USP and other antibacterial drugs, cephalexin capsules USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
  • Cephalexin is contraindicated in patients with known allergy to the cephalosporin group of antibiotics.
  • BEFORE THERAPY WITH CEPHALEXIN IS INSTITUTED, CAREFUL INQUIRY SHOULD BE MADE TO DETERMINE WHETHER THE PATIENT HAS HAD PREVIOUS HYPERSENSITIVITY REACTIONS TO CEPHALEXIN, CEPHALOSPORINS, PENICILLINS, OR OTHER DRUGS. IF THIS PRODUCT IS TO BE GIVEN TO PENICILLIN-SENSITIVE PATIENTS, CAUTION SHOULD BE EXERCISED BECAUSE CROSS-HYPERSENSITIVITY AMONG BETA-LACTAM ANTIBIOTICS HAS BEEN CLEARLY DOCUMENTED AND MAY OCCUR IN UP TO 10% OF PATIENTS WITH A HISTORY OF PENICILLIN ALLERGY. IF AN ALLERGIC REACTION TO CEPHALEXIN OCCURS, DISCONTINUE THE DRUG. SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED.
  • There is some clinical and laboratory evidence of partial cross-allergenicity of the penicillins and the cephalosporins. Patients have been reported to have had severe reactions (including anaphylaxis) to both drugs.
  • Any patient who has demonstrated some form of allergy, particularly to drugs, should receive antibiotics cautiously. No exception should be made with regard to cephalexin.
  • Arrayn- C. difficile
  • C. difficile n- C. difficile
  • If CDAD is suspected or confirmed, ongoing antibiotic use not directed against n n n may need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of n n n , and surgical evaluation should be instituted as clinically indicated.n nn
  • No data
  • No data
  • Signs and Symptoms
  • Treatmentn- Physiciansu2019 Desk Referencen- PDRn- .n- .
  • Unless 5 to 10 times the normal dose of cephalexin has been ingested, gastrointestinal decontamination should not be necessary.
  • Protect the patientu2019s airway and support ventilation and perfusion. Meticulously monitor and maintain, within acceptable limits, the patientu2019s vital signs, blood gases, serum electrolytes, etc. Absorption of drugs from the gastrointestinal tract may be decreased by giving activated charcoal, which, in many cases, is more effective than emesis or lavage; consider charcoal instead of or in addition to gastric emptying. Repeated doses of charcoal over time may hasten elimination of some drugs that have been absorbed. Safeguard the patientu2019s airway when employing gastric emptying or charcoal.
  • Forced diuresis, peritoneal dialysis, hemodialysis, or charcoal hemoperfusion have not been established as beneficial for an overdose of cephalexin; however, it would be extremely unlikely that one of these procedures would be indicated.
  • The oral median lethal dose of cephalexin in rats is >5000 mg/kg.
  • Cephalexin capsules are administered orally.
  • Cephalexin Capsules USP are available in:
  • The 500 mg capsules are light green opaque body imprinted with u201cKLXu201d in black ink and green opaque cap imprinted with u201c141u201d in black ink. They are available as follows:
  • Bottles of 4 NDC 66267-770-04
  • Bottles of 6 NDC 66267-770-06
  • Bottles of 8 NDC 66267-770-08
  • Bottles of 9 NDC 66267-770-09
  • Store at 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F) [See USP Controlled Room Temperature].
  • No data
  • Manufactured for : OrchidPharma, Inc.n n n Princeton, NJ 08540, USAn nn
  • Manufactured by : Hospira Healthcare India Pvt.Ltd.,n n n At Irungattukottai u2013 602 105, Indian nn
  • On behalf of : Orchid Healthcaren n n (A Division of Orchid Chemicals &n n n Pharmaceuticals Ltd.)n n n At Irungattukottai u2013 602 105, Indian nn
  • R06/15
  • No data

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Comparator Sourcing for Clinical Trials

Comparator Sourcing for Clinical Trials

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Name Patient Supply

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Validated Cold Chain Shipment

Validated Cold Chain Shipment

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Clinical Trials Supply

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Pharmaceutical Contract Manufacturing

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