Clindamycin Hydrochloride (Cleocin Hydrochloride)

Trade Name : Cleocin Hydrochloride

Pharmacia and Upjohn Company LLC

CAPSULE

Strength 150 mg/1

CLINDAMYCIN HYDROCHLORIDE Decreased Sebaceous Gland Activity [PE],Lincosamide Antibacterial [EPC],Lincosamides [CS]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Clindamycin Hydrochloride (Cleocin Hydrochloride) which is also known as Cleocin Hydrochloride and Manufactured by Pharmacia and Upjohn Company LLC. It is available in strength of 150 mg/1 per ml. Read more

Clindamycin Hydrochloride (Cleocin Hydrochloride) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of CLEOCIN HCl and other antibacterial drugs, CLEOCIN HCl should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
  • Clostridium difficilen- C. difficle.
  • Because CLEOCIN HCl therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate, as described in the section. It should not be used in patients with nonbacterial infections such as most upper respiratory tract infections.
  • C. difficilen- C. difficile
  • If CDAD is suspected or confirmed, ongoing antibiotic use not directed against . may need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of , and surgical evaluation should be instituted as clinically indicated.
  • Clindamycin hydrochloride is the hydrated hydrochloride salt of clindamycin. Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent compound lincomycin.
  • CLEOCIN HCl Capsules contain clindamycin hydrochloride equivalent to 75 mg, 150 mg, or 300 mg of clindamycin.
  • Inactive ingredients: u2013 corn starch, FD&C blue no. 1, FD&C yellow no. 5, gelatin, lactose, magnesium stearate, and talc; u2013 corn starch, FD&C blue no. 1, FD&C yellow no. 5, gelatin, lactose, magnesium stearate, talc and titanium dioxide; u2013 corn starch, FD&C blue no. 1, gelatin, lactose, magnesium stearate, talc, and titanium dioxide.
  • The structural formula is represented below:
  • The chemical name for clindamycin hydrochloride is Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl--4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L--u03b1-D--octopyranoside monohydrochloride.
  • No data
  • Clindamycin is indicated in the treatment of serious infections caused by susceptible anaerobic bacteria.
  • Clindamycin is also indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci, and staphylococci. Its use should be reserved for penicillin-allergic patients or other patients for whom, in the judgment of the physician, a penicillin is inappropriate. Because of the risk of colitis, as described in the, before selecting clindamycin, the physician should consider the nature of the infection and the suitability of less toxic alternatives (e.g., erythromycin).
  • Anaerobes:
  • Streptococci:
  • Staphylococci:
  • Pneumococci:
  • Bacteriologic studies should be performed to determine the causative organisms and their susceptibility to clindamycin.
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of CLEOCIN HCl and other antibacterial drugs, CLEOCIN HCl should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
  • CLEOCIN HCl is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin.
  • Seen
  • No data
  • The following reactions have been reported with the use of clindamycin.
  • Infections and Infestations: n- Clostridium difficile
  • Gastrointestinal: n- Arrayn- Array
  • Hypersensitivity Reactions:
  • Vesiculobullous rashes, as well as urticaria, have been observed during drug therapy.
  • Severe skin reactions such as Toxic Epidermal Necrolysis, some with fatal outcome, have been reported (See). Cases of Acute Generalized Exanthematous Pustulosis (AGEP), erythema multiforme, some resembling Stevens-Johnson syndrome, anaphylactic shock, anaphylactic reaction and hypersensitivity have also been reported.
  • Skin and Mucous Membranes: n- Array
  • Liver:
  • Renal:
  • Hematopoietic:
  • Immune System
  • Musculoskeletal:
  • Significant mortality was observed in mice at an intravenous dose of 855 mg/kg and in rats at an oral or subcutaneous dose of approximately 2618 mg/kg. In the mice, convulsions and depression were observed.
  • Hemodialysis and peritoneal dialysis are not effective in removing clindamycin from the serum.
  • If significant diarrhea occurs during therapy, this antibiotic should be discontinued (see).
  • Adults: n- Serious infections n- More severe infections
  • Pediatric Patients (n- :n- Serious infections n- More severe infections
  • To avoid the possibility of esophageal irritation, CLEOCIN HCl Capsules should be taken with a full glass of water.
  • CLEOCIN HCl Capsules are not suitable for children who are unable to swallow them whole. The capsules do not provide exact mg/kg doses therefore it may be necessary to use the clindamycin palmitate oral solution in some cases.
  • Serious infections due to anaerobic bacteria are usually treated with CLEOCIN PHOSPHATESterile Solution. However, in clinically appropriate circumstances, the physician may elect to initiate treatment or continue treatment with CLEOCIN HCl Capsules.
  • In cases of u03b2-hemolytic streptococcal infections, treatment should continue for at least 10 days.
  • CLEOCIN HCl Capsules are available in the following strengths, colors and sizes:
  • Store at controlled room temperature 20u00b0 to 25u00b0 C (68u00b0 to 77u00b0 F) [see USP].
  • Rx only
  • No data
  • This product's label may have been updated. For current full prescribing information, please visit www.pfizer.com.
  • LAB-0040-24.0Revised: 2/2020
  • NDC 0009-0331-02
  • Pfizer
  • Cleocin HCln
  • clindamycin hydrochloridecapsules, USP
  • 75 mg*
  • 100 CapsulesRx only
  • NDC 0009-0225-02
  • Pfizer
  • Cleocin HCln
  • clindamycin hydrochloridecapsules, USP
  • 150 mg*
  • 100 CapsulesRx only
  • NDC 0009-0395-14
  • Pfizer
  • Cleocin HCln
  • clindamycin hydrochloridecapsules, USP
  • 300 mg*
  • 100 CapsulesRx only

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