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Dexamethasone (Dexamethasone)

Trade Name : Dexamethasone

Bausch Health Americas, Inc.

TABLET

Strength 1.5 mg/1

DEXAMETHASONE Corticosteroid [EPC],Corticosteroid Hormone Receptor Agonists [MoA]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Dexamethasone (Dexamethasone) which is also known as Dexamethasone and Manufactured by Bausch Health Americas, Inc.. It is available in strength of 1.5 mg/1 per ml. Read more

Dexamethasone (Dexamethasone) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Dexamethasone tablets, USP, 1.5 mg, are for oral administration. Each tablet contains 1.5 mg of dexamethasone. Inactive ingredients are microcrystalline cellulose NF, anhydrous lactose NF, FD&C Red #40 aluminum lake, croscarmellose sodium NF, and magnesium stearate NF. The molecular weight for dexamethasone is 392.47. It is designated chemically as 9-fluoro-11u03b2,17,21-trihydroxy-16u03b1-methylpregna-1,4-diene-3,20-dione. The empirical formula is CHFO and the structural formula is:
  • Dexamethasone, a synthetic adrenocortical steroid, is a white to practically white, odorless, crystalline powder. It is stable in air. It is practically insoluble in water.
  • Glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids that are readily absorbed from the gastrointestinal tract. Glucocorticoids cause varied metabolic effects. In addition, they modify the bodyu2019s immune responses to diverse stimuli. Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have sodium-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs including dexamethasone are primarily used for their anti-inflammatory effects in disorders of many organ systems. At equipotent anti-inflammatory doses, dexamethasone almost completely lacks the sodium-retaining property of hydrocortisone and closely related derivatives of hydrocortisone.
  • No data
  • Systemic fungal infections (see WARNINGS, Fungal infections).Dexamethasone tablets are contraindicated in patients who are hypersensitive to any components of this product.
  • No data
  • No data
  • The following adverse reactions have been reported with dexamethasone or other corticosteroids:
  • Treatment of overdosage is by supportive and symptomatic therapy. In the case of acute overdosage, according to the patientu2019s condition, supportive therapy may include gastric lavage or emesis.
  • For oral administration
  • It Should Be Emphasized That Dosage Requirements Are Variable And Must Be Individualized On The Basis Of The Disease Under Treatment And The Response Of The Patient.
  • After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small decrements at appropriate time intervals until the lowest dosage that maintains an adequate clinical response is reached.
  • Situations which may make dosage adjustments necessary are changes in clinical status secondary to remissions or exacerbations in the disease process, the patientu2019s individual drug responsiveness, and the effect of patient exposure to stressful situations not directly related to the disease entity under treatment. In this latter situation it may be necessary to increase the dosage of the corticosteroid for a period of time consistent with the patientu2019s condition. If after long-term therapy the drug is to be stopped, it is recommended that it be withdrawn gradually rather than abruptly.
  • In the treatment of acute exacerbations of multiple sclerosis, daily doses of 30 mg of dexamethasone for a week followed by 4 to 12 mg every other day for one month have been shown to be effective (see PRECAUTIONS, Neuropsychiatric).
  • In pediatric patients, the initial dose of dexamethasone may vary depending on the specific disease entity being treated. The range of initial doses is 0.02 to 0.3 mg/kg/day in three or four divided doses (0.6 to 9 mg/m2bsa/day).
  • These dose relationships apply only to oral or intravenous administration of these compounds. When these substances or their derivatives are injected intramuscularly or into joint spaces, their relative properties may be greatly altered.
  • In acute, self-limited allergic disorders or acute exacerbations of chronic allergic disorders, the following dosage schedule combining parenteral and oral therapy is suggested: Dexamethasone Sodium Phosphate injection, USP 4 mg per mL:
  • First Day1 or 2 mL, intramuscularlyDexamethasone tablets, USP, 1.5 mg, one-half tablet:Second Day2 tablets in two divided dosesThird Day2 tablets in two divided dosesFourth Day1 tablet in two divided dosesFifth DayOne half tabletSixth DayOne half tabletSeventh DayNo treatmentEighth DayFollow-up visit
  • This schedule is designed to ensure adequate therapy during acute episodes, while minimizing the risk of overdosage in chronic cases.
  • In , Dexamethasone Sodium Phosphate injection, USP is generally administered initially in a dosage of 10 mg intravenously followed by 4 mg every six hours intramuscularly until the symptoms of cerebral edema subside. Response is usually noted within 12 to 24 hours and dosage may be reduced after two to four days and gradually discontinued over a period of five to seven days. For palliative management of patients with recurrent or inoperable brain tumors, maintenance therapy with either Dexamethasone Sodium Phosphate injection, USP or dexamethasone tablets in a dosage of 2 mg two or three times daily may be effective. Dexamethasone suppression tests:
  • 1. Tests for Cushingu2019s syndromeGive 1 mg of dexamethasone tablets, USP orally at 11:00 p.m. Blood is drawn for plasma cortisol determination at 8:00 a.m. the following morning.
  • For greater accuracy, give 0.5 mg of Dexamethasone tablets, USP orally every 6 hours for 48 hours. Twenty-four hour urine collections are made for determination of 17-hydroxycorticosteroid excretion.
  • 2. Test to distinguish Cushingu2019s syndrome due to pituitary ACTH excess from Cushingu2019s syndrome due to other causes.
  • Give 2 mg of Dexamethasone USP orally every 6 hours for 48 hours. Twenty-four hour urine collections are made for determination of 17-hydroxycorticosteroid excretion.
  • Dexamethasone tablets, USP 1.5 mg are scored, pink, pentagonal-shaped tablets debossed u201cECRu201d score u201c86u201d on one side and plain on the other side. These are available in compliance packages of 21 tablets ( NDC 0095-0089-21), 35 tablets ( NDC 0095-0087-35) and 51 tablets (, NDC 0095-0088-51).
  • Store at controlled room temperature 20u00ba to 25u00baC (68u00ba to 77u00baF), [see USP Controlled Room Temperature].
  • Dispense in tight, light resistant container as defined in the USP/NF.
  • Rx Only
  • Keep This and All Medications Out of the Reach of Children.
  • Manufactured for:ECR Pharmaceuticals, a division of Valeant Pharmaceuticals North America LLCBridgewater, NJ 08807 USA
  • Manufactured by:Mikart, Inc.Atlanta, GA 30318
  • u00ae/u2122 are trademarks of Valeant Pharmaceuticals International, Inc. or its affiliates.
  • u00a9 Valeant Pharmaceuticals North America LLC
  • Rev. 11/2017
  • update p/n
  • update p/nn
  • NDC
  • 21 Tablets
  • DexPaku00aen- 6 DAYn- TaperPaku00ae
  • TAPERED ORAL STEROID THERAPY
  • Dexamethasone Tablets USP1.5 mg
  • Rx only
  • See enclosed
  • product literature for additional information.Use Only as Directed by Physician.
  • ECR Pharmaceuticals, a division of
  • Valeant Pharmaceuticals North America LLCBridgewater, NJ 08807 USA
  • u00ae/u2122 are trademarks of Valeant Pharmaceuticals International Inc. or its affiliates.
  • u00a9Valeant Pharmaceuticals North America LLC
  • Store at controlled room temperature20 to 25u00b0C (68 to 77u00b0F), see USP.DISPENSE ONLY IN ORIGINAL PACKAGE
  • NDC
  • 35 Tablets
  • DexPaku00ae n- 10 DAYn- TaperPaku00ae
  • TAPERED ORAL STEROID THERAPY
  • Dexamethasone Tablets USPn- 1.5 mg
  • Rx only
  • See enclosed product literature for additional information.Use Only as Directed by Physician.
  • ECR Pharmaceuticals, a division of Valeant Pharmaceuticals North America LLC Bridgewater, NJ 08807 USA
  • u00ae/u2122 are trademarks of Valeant Pharmaceuticals International, Inc. or its affiliates.
  • u00a9Valeant Pharmaceuticals North America LLC
  • Store at controlled room temperature20 to 25u00b0C (68 to 77u00b0F), see USP.DISPENSE ONLY IN ORIGINAL PACKAGE
  • NDC
  • 51 Tablets
  • DexPaku00ae n- 13 DAYn- TaperPaku00ae
  • TAPERED ORAL STEROID THERAPY
  • Dexamethasone Tablets USPn- 1.5 mg
  • Rx only
  • See enclosed
  • product literature for additional information.
  • Use Only as Directed by Physician.
  • ECR Pharmaceuticals, a division ofValeant Pharmaceuticals North America LLC
  • Bridgewater, NJ 08807 USA
  • u00ae/u2122 are trademarks of Valeant Pharmaceuticals International, Inc. or its affiliates.
  • u00a9Valeant Pharmaceuticals North America LLC
  • Store at controlled room temperature20 to 25u00b0C (68 to 77u00b0F), see USP.DISPENSE ONLY IN ORIGINAL PACKAGE

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