Doxazosin (Doxazosin)

Trade Name : Doxazosin

NuCare Pharmaceuticals, Inc.

TABLET

Strength 4 mg/1

DOXAZOSIN MESYLATE Adrenergic alpha-Antagonists [MoA],alpha-Adrenergic Blocker [EPC]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Doxazosin (Doxazosin) which is also known as Doxazosin and Manufactured by NuCare Pharmaceuticals, Inc.. It is available in strength of 4 mg/1 per ml. Read more

Doxazosin (Doxazosin) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • ntttttt Doxazosin mesylate is a quinazoline compound that is a selective inhibitor of the alphan n n n n n subtype of alpha-adrenergic receptors. The chemical name of doxazosin mesylate is 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl) piperazine methanesulfonate. The empirical formula for doxazosin mesylate is Cn n n n n n Hn n n n n n Nn n n n n n On n n n n n u2022 CHn n n n n n On n n n n n S and the molecular weight is 547.6. It has the following structure:nttttt n nn n nn
  • Doxazosin mesylate is freely soluble in dimethylsulfoxide, soluble in dimethylformamide, slightly soluble in methanol, ethanol, and water (0.8% at 25u00b0C), and very slightly soluble in acetone and methylene chloride. Doxazosin tablets USP are available as colored tablets for oral use and contains 1 mg (White to off white), 2 mg (Cream to yellow), 4 mg (Cream to yellow) and 8 mg (White to off white) of doxazosin as the free base.
  • The inactive ingredients for all tablets are: lactose monohydrate, microcrystalline cellulose, sodium lauryl sulfate, magnesium stearate and sodium starch glycolate. The 2 mg & 4 mg tablet contains ferric oxide yellow.
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  • Doxazosin tablets are contraindicated in patients with a known sensitivity to quinazolines (e.g., prazosin, terazosin), doxazosin, or any of the inert ingredients.
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  • Experience with doxazosin overdosage is limited. Two adolescents, who each intentionally ingested 40 mg doxazosin with diclofenac or acetaminophen, were treated with gastric lavage with activated charcoal and made full recoveries. A two-year-old child who accidently ingested 4 mg doxazosin was treated with gastric lavage and remained normotensive during the five-hour emergency room observation period. A six-month-old child accidentally received a crushed 1 mg tablet of doxazosin and was reported to have been drowsy. A 32-year-old female with chronic renal failure, epilepsy, and depression intentionally ingested 60 mg doxazosin (blood level = 0.9 u00b5g/mL; normal values in hypertensives = 0.02 u00b5g/mL); death was attributed to a grand mal seizure resulting from hypotension. A 39-year-old female who ingested 70 mg doxazosin, alcohol, and Dalmaneu00ae (flurazepam) developed hypotension which responded to fluid therapy.
  • ntttttt The oral LDn n n n n n of doxazosin is greater than 1000 mg/kg in mice and rats. The most likely manifestation of overdosage would be hypotension, for which the usual treatment would be intravenous infusion of fluid. As doxazosin is highly protein bound, dialysis would not be indicated.nttttt n nn n nn
  • DOSAGE MUST BE INDIVIDUALIZED.
  • Concomitant administration of doxazosin tablets with a PDE-5 inhibitor can result in additive blood pressure lowering effects and symptomatic hypotension; therefore, PDE-5 inhibitor therapy should be initiated at the lowest dose in patients taking doxazosin tablets.
  • 4 mg: Cream to yellow coloured, round, biconvex uncoated tablets, debossed with u201cC4u201d on one side and breakline on other side, may have mottled appearance and supplied as follows:
  • NDC 66267-377-90 Bottle of 90
  • NDC 66267-377-30 Bottle of 30
  • Recommended Storage: Store at 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F); excursions permitted to 15u00b0 to 30u00b0C (59u00b0 to 86u00b0F) [see USP Controlled Room Temperature].
  • Manufactured For:
  • Manufactured By:
  • 10 10514 0 627955n n nIssued December 2013n
  • Read this leaflet:
  • You and your doctor should discuss this treatment and your BPH symptoms before you start taking doxazosin tablets and at your regular checkups. This leaflet does NOT take the place of discussions with your doctor.
  • Doxazosin tablets are used to treat both benign prostatic hyperplasia (BPH) and high blood pressure (hypertension). This leaflet describes doxazosin tablets as treatment for BPH (although you may be taking doxazosin tablets for both your BPH and high blood pressure).
  • What is BPH?
  • BPH is an enlargement of the prostate gland. This gland surrounds the tube that drains the urine from the bladder. The symptoms of BPH can be caused by a tensing of the enlarged muscle in the prostate gland which blocks the passage of urine. This can lead to such symptoms as:
  • Treatment Options for BPH
  • The four main treatment options for BPH are:
  • What Doxazosin Tablets Does
  • Doxazosin tablets works on a specific type of muscle found in the prostate, causing it to relax. This in turn decreases the pressure within the prostate, thus improving the flow of urine and your symptoms.
  • Other Important Facts
  • How To Take Doxazosin Tablets and What You Should Know While Taking Doxazosin Tablets for BPH
  • Doxazosin Tablets Can Cause a Sudden Drop in Blood Pressure After the VERY FIRST DOSE.
  • Your blood pressure should be checked when you start taking doxazosin tablets even if you do not have high blood pressure (hypertension). Your doctor will discuss with you the details of how blood pressure is measured.
  • Blood Pressure Measurement:
  • You can take doxazosin tablets either in the morning or at bedtime and it will be equally effective. If you take doxazosin tablets at bedtime but need to get up from bed to go to the bathroom, get up slowly and cautiously until you are sure how the medication affects you. It is important to get up slowly from a chair or bed at any time until you learn how you react to doxazosin tablets. You should not drive or do any hazardous tasks until you are used to the effects of the medication. If you begin to feel dizzy, sit or lie down until you feel better.
  • FOR MORE INFORMATION ABOUT DOXAZOSIN TABLETS AND BPH TALK WITH YOUR DOCTOR, NURSE, PHARMACIST OR OTHER HEALTH CARE PROVIDER.
  • Manufactured For:
  • Manufactured By:
  • 10 10514 0 627955
  • Issued December 2013
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