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Echothiophate Iodide - Ophthalmic (Phospholine Iodide)

Trade Name : Phospholine Iodide

Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.

KIT

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Echothiophate Iodide - Ophthalmic (Phospholine Iodide) which is also known as Phospholine Iodide and Manufactured by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.. It is available in strength of per ml. Read more

Echothiophate Iodide - Ophthalmic (Phospholine Iodide) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Rx Only
  • Chemical name: (2-mercaptoethyl) trimethylammonium iodide O,O-diethyl phosphorothioate
  • Structural formula
  • Echothiophate iodide for ophthalmic solution occurs as a white, crystalline, water-soluble, hygroscopic solid having a slight mercaptan-like odor. When freeze-dried in the presence of potassium acetate, the mixture appears as a white amorphous deposit on the walls of the bottle.
  • Each package contains materials for dispensing 5 mL of eyedrops: (1) bottle containing sterile echothiophate iodide for ophthalmic solution 6.25 mg (0.125%) with 40 mg potassium acetate. Sodium hydroxide or acetic acid may have been incorporated to adjust pH during manufacturing; (2) a 5 mL bottle of sterile diluent containing chlorobutanol (chloral derivative), 0.55%; mannitol, 1.2%; boric acid, 0.06%; and sodium phosphate, 0.026%; (3) sterilized dropper.
  • Echothiophate iodide for ophthalmic solution is a long-acting cholinesterase inhibitor for topical use which enhances the effect of endogenously liberated acetylcholine in iris, ciliary muscle, and other parasympathetically innervated structures of the eye. It thereby causes miosis, increase in facility of outflow of aqueous humor, fall in intraocular pressure (IOP), and potentiation of accommodation.
  • Echothiophate iodide for ophthalmic solution will depress both plasma and erythrocyte cholinesterase levels in most patients after a few weeks of eyedrop therapy.
  • No data
  • No data
  • 1. Succinylcholine should be administered only with great caution, if at all, prior to or during general anesthesia to patients receiving anticholinesterase medication because of possible respiratory or cardiovascular collapse.
  • 2. Caution should be observed in treating elevated IOP with echothiophate iodide for ophthalmic solution in patients who are at the same time undergoing treatment with systemic anticholinesterase medications, because of possible adverse additive effects.
  • No data
  • 1. Although the relationship, if any, of retinal detachment to the administration of echothiophate iodide for ophthalmic solution has not been established, retinal detachment has been reported in a few cases during the use of echothiophate iodide for ophthalmic solution in adult patients without a previous history of this disorder.
  • 2. Stinging, burning, lacrimation, lid muscle twitching, conjunctival and ciliary redness, browache, induced myopia with visual blurring may occur.
  • 3. Activation of latent iritis or uveitis may occur.
  • 4. Iris cysts may form, and if treatment is continued, may enlarge and obscure vision. This occurrence is more frequent in children. The cysts usually shrink upon discontinuance of the medication or by reducing the frequency of instillation. Rarely, they may rupture or break free into the aqueous. Regular examinations are advisable when the drug is being prescribed for the treatment of accommodative esotropia.
  • 5. Prolonged use may cause conjunctival thickening, obstruction of nasolacrimal canals.
  • 6. Lens opacities have been reported with echothiophate iodide.
  • 7. Paradoxical increase in IOP may follow anticholinesterase instillation. This may be alleviated by prescribing a sympathomimetic mydriatic such as phenylephrine.
  • 8. Cardiac irregularities.
  • No data
  • Each package contains sterile echothiophate iodide for ophthalmic solution, sterile diluent, and dropper for dispensing 5 mL eyedrops.
  • White amorphous deposit on bottle walls. Aluminum crimp seal is green.
  • Prior to reconstitution: Store under refrigeration (2u00b0 to 8u00b0 C).
  • After reconstitution: Store at room temperature (approximately 25u00b0 C). Do not refrigerate. Discard any unused solution after 4 weeks.
  • This product's label may have been updated. For current full prescribing information, please visit www.pfizer.com.
  • LAB-0813-3.0 Revised August 2018
  • Pfizer
  • NDC 0046-1065-05
  • Phospholine Iodiden (echothiophate iodide for ophthalmic solution)
  • 0.125% (1/8%) 6.25 mg/5 mL
  • This package contains sterile echothiophate iodide with 40 mg potassium acetate (sodium hydroxide or acetic acid may have been incorporated to adjust pH during manufacturing) and 5 mL (1/6 fl oz) sterile aqueous diluent, in individual bottles for dispensing 5 mL of eyedrops of strength shown when reconstituted.
  • Rx only
  • NDC 0046-1162-05 STERILE DILUENT FOR PREPARING Phospholine Iodiden (echothiophate iodide for ophthalmic solution)
  • 5 mL (1/6 fl oz)
  • EYEDROPS
  • NDC 0046-1465-05
  • Rx only
  • Phospholine Iodiden (echothiophate iodide for ophthalmic solution)
  • 0.125% (1/8%) 6.25 mg/5 mL
  • Each 5 mL contains 6.25 mg of echothiophate iodide With 40 mg Potassium Acetate for preparing 5 mL eyedrops. See accompanying descriptive literature.

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