Heparin Sodium (Heparin Sodium)

Trade Name : Heparin Sodium

Pfizer Laboratories Div Pfizer Inc

INJECTION

Strength 1000 [USP'U]/mL

HEPARIN SODIUM Anti-coagulant [EPC],Heparin [CS],Unfractionated Heparin [EPC]

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Product information is meant for

Wholesalers Suppliers Exporters Doctors MOH Tender Supplies Hospitals Brand CROs Comparator Supplies Generic Cooperate Sourcing Individual Patients Indian Institutional Buyers

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Heparin Sodium (Heparin Sodium) which is also known as Heparin Sodium and Manufactured by Pfizer Laboratories Div Pfizer Inc. It is available in strength of 1000 [USP'U]/mL per ml. Read more

Heparin Sodium (Heparin Sodium) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials. Click to know price. Read less

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No data

No data

HEPARIN SODIUM INJECTION is indicated for:
HEPARIN SODIUM INJECTION is an anticoagulant indicated for ():

Prophylaxis and treatment of venous thrombosis and pulmonary embolism
Prophylaxis and treatment of the thromboembolic complications associated with atrial fibrillation
Treatment of acute and chronic consumption coagulopathies
Prevention of clotting in arterial and cardiac surgery
Prophylaxis and treatment of peripheral arterial embolism
Anticoagulant use in transfusion, extracorporeal circulation, and dialysis procedures

Recommended Adult Dosages:

HEPARIN SODIUM INJECTION is available as:

The use of HEPARIN SODIUM INJECTION is contraindicated in patients:

History of heparin-induced thrombocytopenia (HIT) or heparin-induced thrombocytopenia and thrombosis (HITTS) ()
History of thrombocytopenia with pentosan polysulfate ()
Known hypersensitivity to heparin or pork products ()
In whom suitable blood coagulation tests cannot be performed at appropriate intervals ()
An uncontrollable bleeding state, except when this is due to disseminated intravascular coagulation ()

No data

Fatal Medication Errors: Confirm choice of correct strength prior to administration ()
Hemorrhage: Hemorrhage, including fatal events, has occurred in patients receiving heparin. Use caution in conditions with increased risk of hemorrhage ()
HIT and HITTS: Monitor for signs and symptoms and discontinue if indicative of HIT and HITTS ()
Benzyl Alcohol Toxicity: Use preservative-free formulation in neonates and infants ()
Monitoring: Blood coagulation tests guide therapy for full-dose heparin. Periodically monitor platelet count, hematocrit, and occult blood in stool in all patients receiving heparin (, )

The following clinically significant adverse reactions are described elsewhere in the labeling:
The following adverse reactions have been identified during post approval use of HEPARIN SODIUM INJECTION. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency.
Most common adverse reactions are hemorrhage, thrombocytopenia, HIT and HITTS, injection site irritation, general hypersensitivity reactions, and elevations of aminotransferase levels. ()
To report SUSPECTED ADVERSE REACTIONS, contact Pfizer at 1-800-438-1985 or FDA at 1-800-FDA-1088 or .

Drugs that interfere with coagulation, platelet aggregation or drugs that counteract coagulation may induce bleeding ()

No data

Pregnancy: Preservative-free formulation recommended. ()
Lactation: Preservative-free formulation recommended. ()
Pediatric Use: Use preservative-free formulation in neonates and infants ()

Bleeding is the chief sign of heparin overdosage.
Neutralization of Heparin Effect
When clinical circumstances (bleeding) require reversal of the heparin effect, protamine sulfate (1% solution) by slow infusion will neutralize heparin sodium. should be administered, , in any 10 minute period. Each mg of protamine sulfate neutralizes approximately 100 USP heparin units. The amount of protamine required decreases over time as heparin is metabolized. Although the metabolism of heparin is complex, it may, for the purpose of choosing a protamine dose, be assumed to have a half-life of about 30 minutes after intravenous injection. Because fatal reactions often resembling anaphylaxis have been reported with protamine, it should be given only when resuscitation techniques and treatment of anaphylactoid shock are readily available. For additional information, consult the prescribing information for protamine sulfate injection.

Heparin is a heterogenous group of straight-chain anionic mucopolysaccharides, called glycosaminoglycans, possessing anticoagulant properties. It is composed of polymers of alternating derivations of u03b1-D-glucosamido (-sulfated -sulfated or acetylated) and -sulfated uronic acid (u03b1-L-iduronic acid or u03b2-D-glucuronic acid).
Structure of heparin sodium (representative subunits):
HEPARIN SODIUM INJECTION is a sterile preparation of heparin sodium derived from porcine intestinal tissue, standardized for anticoagulant activity, in water for injection. It is intended for intravenous or deep subcutaneous administration. The potency is determined by a biological assay using a USP reference standard based on units of heparin activity per milligram.
For formulations preserved with benzyl alcohol, each mL of the 1,000 UPS units and 5,000 USP units per mL preparations contains: heparin sodium 1,000 UPS units or 5,000 USP units; 9 mg sodium chloride; 9.45 mg benzyl alcohol added as preservative. Each mL of the 10,000 USP units per mL preparations contains: heparin sodium 10,000 USP units; 9.45 mg benzyl alcohol added as preservative.
The preservative-free product contains (per mL): 1,000 USP units of heparin sodium and 9 mg sodium chloride.
When necessary, the pH of HEPARIN SODIUM INJECTION is adjusted with hydrochloric acid and/or sodium hydroxide. The pH range is 5.0 to 7.5.

No data

No long-term studies in animals have been performed to evaluate carcinogenic potential of heparin. No studies in animals have been performed addressing mutagenesis or impairment of fertility.

HEPARIN SODIUM INJECTION is available in the following strengths and package sizes:
HEPARIN SODIUM INJECTION preserved with is available in the following strengths and package sizes:
Store at 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F) [see USP Controlled Room Temperature]. Use only if solution is clear and the seal is intact. Do not use if solution is discolored or contains a precipitate.

No data

LAB-0414-6.0

NDC 0069-0058-02
Multidose Vial
HeparinSodium Injection, USP
10,000 USP units /10 mL(1,000 USP units/mL)
Warning: ContainsBenzyl Alcohol
Rx only

NDC 0069-0058-01Contains 25 of NDC 0069-0058-02Rx only
Twenty-fiveu201410 mL Multidose Vials
HeparinSodium Injection, USP
10,000 USP units/10 mL(1,000 USP units per mL)
Derived from porcine intestinal tissue
For subcutaneous or intravenous use
Warning: Contains Benzyl Alcohol
NOT for Lock Flush
Pfizer Injectables

NDC 0069-0059-02
Multidose Vial
HeparinSodium Injection, USP
50,000 USP units /10 mL(1,000 USP units/mL)
Warning: ContainsBenzyl Alcohol
Rx only

NDC 0069-0059-01Contains 25 of NDC 0069-0059-02Rx only
Twenty-fiveu201410 mL Multidose Vials
HeparinSodium Injection, USP
50,000 USP units/10 mL(5,000 USP units per mL)
Derived from porcine intestinal tissue
For subcutaneous or intravenous use
Warning: Contains Benzyl Alcohol
NOT for Lock Flush
Pfizer Injectables

NDC 0069-0062-02
Multidose Vial
HeparinSodium Injection, USP
10,000 USP units / mL
Warning: ContainsBenzyl Alcohol
Rx only

NDC 0069-0062-01Contains 25 ofNDC 0069-0062-02Rx only
Twenty-fiveu20141 mL Multidose Vials
HeparinSodium Injection, USP
10,000 USP units /mL
Derived from porcine intestinal tissue
For subcutaneous or intravenous use
Warning: Contains Benzyl Alcohol
Pfizer Injectables
NOT for Lock Flush

NDC 0069-0043-02
Single Dose Vial
HeparinSodium Injection, USP
2,000 USP units / 2 mL(1,000 USP units/mL)
Preservative-FreeRx only

NDC 0069-0043-01Contains 25 ofNDC 0069-0043-02Rx only
Twenty-fiveu20142 mL Single Dose Vials
HeparinSodium Injection, USP
2,000 USP units /2 mL(1,000 USP units per mL)
Derived from porcine intestinal tissue
For subcutaneous or intravenous use
Pfizer Injectables
Preservative-Free
NOT for Lock Flush

NDC 0069-0137-01
HEPARINSodium Injection, USP
30,000 USP units/30 mL(1,000 USP units/mL)
Warning: Contains Benzyl Alcohol
Multidose Vial
NOT for Lock Flush

Tenu201430 mL Multidose Vials
NDC 0069-0137-03Contains 10 ofNDC 0069-0137-01
HEPARINSodium Injection, USP
30,000n- 30 mLn- (1,000n- per mL)
Derived from porcine intestinal tissue
For subcutaneous or intravenous use
Pfizer Injectables
Warning: Contains Benzyl Alcohol
NOT for Lock Flush
Rx only
Multidose Vials

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Heparin Sodium (Heparin Sodium)

Trade Name : Heparin Sodium

INJECTION

Delivery Process

Product information is meant for

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

Packaging and Delivery

About GNH

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Heparin Sodium (Heparin Sodium)

Trade Name : Heparin Sodium

INJECTION

Delivery Process

Product information is meant for

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

Packaging and Delivery

About GNH

Similar Products

Desogestrel And Ethinyl Estradiol (Emoquette)

Diphenoxylate Hydrochloride And Atropine Sulfate (Diphenoxylate Hydrochloride And Atropine Sulfate)

Fluoxetine Hydrochloride (Fluoxetine)

Metoprolol Succinate (Metoprolol Succinate)

Losartan Potassium (Losartan Potassium)

Browse Our Services And Processes

Disclaimer

Browse from other international pharmaceuticals

General

US NDC

Canadian DIN

Swiss Drugs

NZ Drugs

FAQ

Can’t find what you’re looking for?

COMPANY

SERVICES

QUICK LINKS

CONTACT US

Can’t find what
you’re looking for?