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Indinavir Sulfate (Crixivan)

Trade Name : CRIXIVAN

Merck Sharp & Dohme Corp.

CAPSULE

Strength 200 mg/1

INDINAVIR SULFATE HIV Protease Inhibitors [MoA],Protease Inhibitor [EPC],Cytochrome P450 3A4 Inhibitors [MoA]

Delivery Process

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Product information is meant for

Wholesalers Suppliers Exporters Doctors MOH Tender Supplies Hospitals Brand CROs Comparator Supplies Generic Cooperate Sourcing Individual Patients Indian Institutional Buyers

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Indinavir Sulfate (Crixivan) which is also known as CRIXIVAN and Manufactured by Merck Sharp & Dohme Corp.. It is available in strength of 200 mg/1 per ml. Read more

Indinavir Sulfate (Crixivan) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • CRIXIVAN (indinavir sulfate) is an inhibitor of the human immunodeficiency virus (HIV) protease. CRIXIVAN Capsules are formulated as a sulfate salt and are available for oral administration in strengths of 200 and 400 mg of indinavir (corresponding to 250 and 500 mg indinavir sulfate, respectively). Each capsule also contains the inactive ingredients anhydrous lactose and magnesium stearate. The capsule shell has the following inactive ingredients and dyes: gelatin and titanium dioxide.
  • The chemical name for indinavir sulfate is [1(1,2),5()]-2,3,5-trideoxy--(2,3-dihydro-2-hydroxy-1-inden-1-yl)-5-[2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D--pentonamide sulfate (1:1) salt. Indinavir sulfate has the following structural formula:
  • Indinavir sulfate is a white to off-white, hygroscopic, crystalline powder with the molecular formula CHNO u2022 HSO and a molecular weight of 711.88. It is very soluble in water and in methanol.
  • No data
  • No data
  • CRIXIVAN in combination with antiretroviral agents is indicated for the treatment of HIV infection.
  • This indication is based on two clinical trials of approximately 1 year duration that demonstrated: 1) a reduction in the risk of AIDS-defining illnesses or death; 2) a prolonged suppression of HIV RNA.
  • CRIXIVAN is contraindicated in patients with clinically significant hypersensitivity to any of its components.
  • Inhibition of CYP3A4 by CRIXIVAN can result in elevated plasma concentrations of the following drugs, potentially causing serious and/or life-threatening reactions:
  • ALERT: Find out about medicines that should NOT be taken with CRIXIVAN.
  • No data
  • No data
  • There have been more than 60 reports of acute or chronic human overdosage (up to 23 times the recommended total daily dose of 2400 mg) with CRIXIVAN. The most commonly reported symptoms were renal (e.g., nephrolithiasis/urolithiasis, flank pain, hematuria) and gastrointestinal (e.g., nausea, vomiting, diarrhea).
  • It is not known whether CRIXIVAN is dialyzable by peritoneal or hemodialysis.
  • The recommended dosage of CRIXIVAN is 800 mg (usually 400-mg capsules) orally every 8 hours.
  • CRIXIVAN must be taken at intervals of 8 hours. For optimal absorption, CRIXIVAN should be administered without food but with water 1 hour before or 2 hours after a meal. Alternatively, CRIXIVAN may be administered with other liquids such as skim milk, juice, coffee, or tea, or with a light meal, e.g., dry toast with jelly, juice, and coffee with skim milk and sugar; or corn flakes, skim milk and sugar. (See .)
  • To ensure adequate hydration, it is recommended that adults drink at least 1.5 liters (approximately 48 ounces) of liquids during the course of 24 hours.
  • CRIXIVAN Capsules are supplied as follows:
  • No. 3756 u2014 200 mg capsules: semi-translucent white capsules coded in blue. Available as:
  • Arrayn- NDC
  • No. 3758 u2014 400 mg capsules: semi-translucent white capsules coded in green. Available as:
  • Arrayn- NDC
  • Bottles:
  • CRIXIVAN Capsules are sensitive to moisture. CRIXIVAN should be dispensed and stored in the original container. The desiccant should remain in the original bottle.
  • Dist. by: Merck Sharp & Dohme Corp., a subsidiary of n Whitehouse Station, NJ 08889, USA
  • For patent information: www.merck.com/product/patent/home.html
  • Copyright u00a9 1996-2018 Merck Sharp & Dohme Corp., a subsidiary of n All rights reserved.
  • Revised: 05/2018
  • uspi-mk0639-c-1805r019
  • Arrayn- Array
  • Arrayn- ALERT: Find out about medicines that should NOT be taken with CRIXIVAN.
  • Please read this information before you start taking CRIXIVAN. Also, read the leaflet each time you renew your prescription, just in case anything has changed. Remember, this leaflet does not take the place of careful discussions with your doctor. You and your doctor should discuss CRIXIVAN when you start taking your medication and at regular checkups. You should remain under a doctor's care when using CRIXIVAN and should not change or stop treatment without first talking with your doctor.
  • Distributed by:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.Whitehouse Station, NJ 08889, USA
  • For patent information: www.merck.com/product/patent/home.html
  • The trademarks depicted herein are owned by their respective companies.
  • Copyright u00a9 1996-2016 Merck Sharp & Dohme Corp., a subsidiary of n All rights reserved.
  • Revised 09/2016
  • usppi-mk0639-c-1609r018
  • No data
  • NDC 0006-0571-43
  • Crixivann- (Indinavir Sulfate) Capsules
  • 200 mg
  • ALERTFind out about medicines that should NOT be taken with CRIXIVAN.
  • Note to Pharmacist: Do not cover ALERT box with Pharmacy label.
  • Each capsule contains indinavir 200 mg (corresponding to indinavirsulfate 250 mg). Store in a tightly closed container at roomtemperature,15-30u00b0C (59-86u00b0F). Protect from moisture.CRIXIVAN Capsules are sensitive tomoisture and should be dispensed andstored in the original container.The desiccant should remain in theoriginal bottle.
  • USUAL DOSAGE: See Package Insert.
  • Rx only
  • 360 Capsules
  • NDC 0006-0573-62
  • Crixivann- (Indinavir Sulfate) Capsules
  • 400 mg
  • ALERTFind out about medicines that should NOT be taken with CRIXIVAN.
  • Note to Pharmacist: Do not cover ALERT box with Pharmacy label.
  • Each capsule contains indinavir 400 mg (corresponding to indinavirsulfate 500 mg). Store in a tightly closed container at roomtemperature,15-30u00b0C (59-86u00b0F).Protect from moisture. CRIXIVAN Capsulesare sensitive to moisture and should bedispensed and stored in the originalcontainer. The desiccant should remainin the original bottle.
  • USUAL DOSAGE: See Package Insert.
  • Rx only
  • 180 Capsules

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With shifting of pharma industry from synthetic molecules to biologic

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