Ivermectin (Stromectol)

Trade Name : STROMECTOL

Merck Sharp & Dohme Corp.

TABLET

Strength 3 mg/1

IVERMECTIN Antiparasitic [EPC],Pediculicide [EPC]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Ivermectin (Stromectol) which is also known as STROMECTOL and Manufactured by Merck Sharp & Dohme Corp.. It is available in strength of 3 mg/1 per ml. Read more

Ivermectin (Stromectol) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • STROMECTOL (Ivermectin) is a semisynthetic, anthelmintic agent for oral administration. Ivermectin is derived from the avermectins, a class of highly active broad-spectrum, anti-parasitic agents isolated from the fermentation products of . Ivermectin is a mixture containing at least 90% 5--demethyl-22,23-dihydroavermectin A and less than 10% 5--demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A, generally referred to as 22,23-dihydroavermectin B and B, or HB and HB, respectively. The respective empirical formulas are CHO and CHO, with molecular weights of 875.10 and 861.07, respectively. The structural formulas are:
  • Ivermectin is a white to yellowish-white, nonhygroscopic, crystalline powder with a melting point of about 155u00b0C. It is insoluble in water but is freely soluble in methanol and soluble in 95% ethanol.
  • STROMECTOL is available in 3-mg tablets containing the following inactive ingredients: microcrystalline cellulose, pregelatinized starch, magnesium stearate, butylated hydroxyanisole, and citric acid powder (anhydrous).
  • No data
  • STROMECTOL is indicated for the treatment of the following infections:
  • Strongyloidiasis of the intestinal tractn- Strongyloides stercoralis
  • This indication is based on clinical studies of both comparative and open-label designs, in which 64-100% of infected patients were cured following a single 200-mcg/kg dose of ivermectin. (See .)
  • Onchocerciasisn- Onchocerca volvulus
  • This indication is based on randomized, double-blind, placebo-controlled and comparative studies conducted in 1427 patients in onchocerciasis-endemic areas of West Africa. The comparative studies used diethylcarbamazine citrate (DEC-C).
  • NOTE: STROMECTOL has no activity against adult parasites. The adult parasites reside in subcutaneous nodules which are infrequently palpable. Surgical excision of these nodules (nodulectomy) may be considered in the management of patients with onchocerciasis, since this procedure will eliminate the microfilariae-producing adult parasites.
  • STROMECTOL is contraindicated in patients who are hypersensitive to any component of this product.
  • Historical data have shown that microfilaricidal drugs, such as diethylcarbamazine citrate (DEC-C), might cause cutaneous and/or systemic reactions of varying severity (the Mazzotti reaction) and ophthalmological reactions in patients with onchocerciasis. These reactions are probably due to allergic and inflammatory responses to the death of microfilariae. Patients treated with STROMECTOL for onchocerciasis may experience these reactions in addition to clinical adverse reactions possibly, probably, or definitely related to the drug itself. (See .)
  • The treatment of severe Mazzotti reactions has not been subjected to controlled clinical trials. Oral hydration, recumbency, intravenous normal saline, and/or parenteral corticosteroids have been used to treat postural hypotension. Antihistamines and/or aspirin have been used for most mild to moderate cases.
  • No data
  • No data
  • Significant lethality was observed in mice and rats after single oral doses of 25 to 50u00a0mg/kg and 40 to 50u00a0mg/kg, respectively. No significant lethality was observed in dogs after single oral doses of up to 10u00a0mg/kg. At these doses, the treatment-related signs that were observed in these animals include ataxia, bradypnea, tremors, ptosis, decreased activity, emesis, and mydriasis.
  • In accidental intoxication with, or significant exposure to, unknown quantities of veterinary formulations of ivermectin in humans, either by ingestion, inhalation, injection, or exposure to body surfaces, the following adverse effects have been reported most frequently: rash, edema, headache, dizziness, asthenia, nausea, vomiting, and diarrhea. Other adverse effects that have been reported include: seizure, ataxia, dyspnea, abdominal pain, paresthesia, urticaria, and contact dermatitis.
  • In case of accidental poisoning, supportive therapy, if indicated, should include parenteral fluids and electrolytes, respiratory support (oxygen and mechanical ventilation if necessary) and pressor agents if clinically significant hypotension is present. Induction of emesis and/or gastric lavage as soon as possible, followed by purgatives and other routine anti-poison measures, may be indicated if needed to prevent absorption of ingested material.
  • No data
  • No. 8495 u2014 Tablets STROMECTOL 3u00a0mg are white, round, flat, bevel-edged tablets coded MSD on one side and 32 on the other side. They are supplied as follows:
  • NDC
  • Store at temperatures below 30u00b0C (86u00b0F).
  • Dist. by: Merck Sharp & Dohme Corp., a subsidiary ofn Whitehouse Station, NJ 08889, USA
  • Manufactured by: Merck Sharp & Dohme BV Waarderweg 39 2031 BN Haarlem Netherlands
  • For patent information: www.merck.com/product/patent/home.html
  • Copyright u00a9 1996-2018 Merck Sharp & Dohme Corp., a subsidiary of . All rights reserved.
  • Revised: 02/2018
  • uspi-mk0933-t-1802r020
  • Printed in the Netherlands
  • Stromectol 3 mg(Ivermectin Tablets)
  • Manuf. by:Merck Sharp & Dohme BV2031 BN Haarlem, NetherlandsttttttIvermectin (active ingred.)Made in Macao. Formulated inThe Netherlands.
  • Dist. by: Merck Sharp & Dohme Corp., a subsidiary ofMERCK & CO., INC.Whitehouse Station, NJ 08889, USA
  • Each tablet contains 3 mg of ivermectin.USUAL DOSAGE: See accompanying circular.Store at temperatures below 30u00b0C (86u00b0F).Rx only
  • 20 Tablets(2 Foil Strips of 10 tablets each)
  • 32
  • NDC 0006-0032-20
  • This is a bulk package and not intendedfor dispensing. The aluminum foil strip isnot child resistant. Remove tablets fromaluminum foil strip and dispense tabletsin appropriate container.

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