Trade Name: TALTZ

Following information is meant for : Wholesalers, Suppliers, Exporters, Doctors, CROs, Comparator Supplies, Hospitals, MOH Tender Supplies, Generic, Brand, Cooperate Sourcing, India, Institutional Buyers.

Manufacturer: Eli Lilly and Company

Presentation: INJECTION, SOLUTION, HUMAN PRESCRIPTION DRUG

Strength: 80 mg/mL

Storage and handling

IXEKIZUMAB Interleukin-17A Antagonist [EPC],Interleukin-17A Antagonists [MoA]

Disclaimer:
  1. These products are NOT FOR SALE in US territories. We offer them for Exports outside of US Territories to Trade Professionals or patients with a valid prescription.
  2. Trademark shown are property of their respective owners and GNH India does not lay any claim on them.
  3. Read more
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  • TALTZ is a humanized interleukin-17A antagonist indicated for the treatment of adults with:n
  • moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy. ()n
  • active psoriatic arthritis. ()n
  • active ankylosing spondylitis. ()n
  • Plaque Psoriasisn
  • Psoriatic Arthritisn
  • Ankylosing Spondylitisn
  • TALTZ is a clear and colorless to slightly yellow solution available as:n
  • Autoinjectorn
  • Prefilled Syringen
  • Autoinjectorn
  • Prefilled Syringen
  • TALTZ is contraindicated in patients with a previous serious hypersensitivity reaction, such as anaphylaxis, to ixekizumab or to any of the excipients .n
  • Serious hypersensitivity reaction to ixekizumab or to any of the excipients. ()n
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  • Infections
  • Tuberculosis (TB)
  • Hypersensitivity
  • Inflammatory Bowel Disease
  • The following adverse drug reactions are discussed in greater detail in other sections of the label:n
  • Most common (u22651%) adverse reactions associated with TALTZ treatment are injection site reactions, upper respiratory tract infections, nausea, and tinea infections. ()n
  • To report SUSPECTED ADVERSE REACTIONS, contact Eli Lilly and Company at 1-800-545-5979 (1-800-LillyRx) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
  • Live Vaccines: Live vaccines should not be given with TALTZ. ()n
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  • In the event of overdosage, monitor the patient for any signs or symptoms of adverse reactions and institute appropriate symptomatic treatment immediately.n
  • Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) with neutralizing activity against IL-17A. Ixekizumab is produced by recombinant DNA technology in a recombinant mammalian cell line and purified using standard technology for bioprocessing. Ixekizumab is comprised of two identical light chain polypeptides of 219 amino acids each and two identical heavy chain polypeptides of 445 amino acids each, and has a molecular weight of 146,158 Daltons for the protein backbone of the molecule.n
  • TALTZ injection is a sterile, preservative free, clear and colorless to slightly yellow solution, for subcutaneous use available as 80u00a0mg of ixekizumab in a 1u00a0mL single-dose prefilled autoinjector or a single-dose prefilled syringe. The prefilled autoinjector and prefilled syringe each contain a 1u00a0mL glass syringe with a fixed 27 gauge u00bdu00a0inch needle. The TALTZ 80u00a0mg prefilled autoinjector and prefilled syringe are manufactured to deliver 80u00a0mg of ixekizumab.n
  • Each mL is composed of ixekizumab (80u00a0mg); Citric Acid Anhydrous, USP (0.51u00a0mg); Polysorbate 80, USP (0.3u00a0mg); Sodium Chloride, USP (11.69u00a0mg); Sodium Citrate Dihydrate, USP (5.11u00a0mg); and Water for Injection, USP. The TALTZ solution has a pH of 5.3 u2013 6.1.n
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  • Animal studies have not been conducted to evaluate the carcinogenic or mutagenic potential of TALTZ. Moreover published literature is mixed on potential effects on malignancy risk due to the inhibition of IL-17A activity, the pharmacological action of TALTZ. Some published literature suggests that IL-17A directly promotes cancer cell invasion, suggesting a potential beneficial effect by TALTZ, whereas other reports indicate IL-17A promotes T-cell mediated tumor rejection, suggesting a potential adverse effect by TALTZ. However, neutralization of IL-17A with TALTZ has not been studied in these models. Depletion of IL-17A with a neutralizing antibody inhibited tumor development in mice, suggesting a potential beneficial effect by TALTZ. The relevance of experimental findings in mouse models for malignancy risk in humans is unknown.n
  • No effects on fertility parameters such as reproductive organs, menstrual cycle length, or sperm analysis were observed in sexually mature cynomolgus monkeys that were administered ixekizumab for 13 weeks at a subcutaneous dose of 50u00a0mg/kg/week (19 times the MRHD on a mg/kg basis). The monkeys were not mated to evaluate fertility.n
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  • Advise the patient and/or caregiver to read the FDA-approved patient labeling before the patient starts using TALTZ, and each time the prescription is renewed, as there may be new information they need to know.n
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  • open heren
  • 1 Single-Dose prefilled autoinjectorn
  • taltzn
  • (ixekizumab) injectionn
  • 80 mg/mLn
  • For Subcutaneous Use Onlyn
  • Single-Dose Onlyn
  • NDC 0002-1445-11n
  • Each prefilled autoinjector contains 80 mg of TALTZ.n
  • Rx Onlyn
  • Dispense enclosed Medication Guide to each patient.n
  • Lillyn
  • open heren
  • 1 Single-Dose prefilled syringen
  • taltzn
  • (ixekizumab) injectionn
  • 80 mg/mLn
  • For Subcutaneous Use Onlyn
  • Single-Dose Onlyn
  • NDC 0002-7724-11n
  • Each prefilled syringe contains 80 mg of TALTZ.n
  • Rx Onlyn
  • Dispense enclosed Medication Guide to each patient.n
  • Lillyn

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GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler, Supplier, Exporters from India of ixekizumab (TALTZ) which is also known as TALTZ and Manufactured by Eli Lilly and Company. It is available in strength of 80 mg/mL.

ixekizumab (TALTZ) is supplied for Tenders, Emergency imports, Un - licensed, Specials, Orphan drug, Name patient line, RLD supplies, Reference listed drugs, Comparator Drug, Bio-Similar, Innovator samples, For Clinical trials. Click to know price.

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