Methenamine Hippurate (Methenamine Hippurate)

Trade Name : Methenamine Hippurate

Impax Generics

TABLET

Strength 1 g/1

METHENAMINE HIPPURATE

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Methenamine Hippurate (Methenamine Hippurate) which is also known as Methenamine Hippurate and Manufactured by Impax Generics. It is available in strength of 1 g/1 per ml. Read more

Methenamine Hippurate (Methenamine Hippurate) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials. Click to know price. Read less

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To reduce the development of drug-resistant bacteria and maintain the effectiveness ofu00a0methenamine hippurate tablets, USPu00a0and other antibacterial drugs, methenamine hippurate tablets, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

Methenamine hippurate tablets, USP are available as 1 g oval shaped, scored and peach colored tablets. Chemically, methenamine hippurate is Hexamethylenetetramine monohippurate. The molecular formula of methenamine hippurate is CHNO and molecular weight is 319.36. Its structural formula is:
Eachu00a0methenamine hippurate tablet, USP intended for oral administration contains 1 g of methenamine hippurate. In addition, it also contains the following inactive ingredients: colloidal silicon dioxide, magnesium stearate, povidone K29/32, saccharin sodium and FD&C Yellow #6 Aluminum Lake as a color additive.
Meets USP Dissolution Test 2.

Microbiology: n- E. colin- Enterobacter aerogenesn- Proteusn- Pseudomonas
Human Pharmacology

Methenamine hippurate tablets, USP are indicated for prophylactic or suppressive treatment of frequently recurring urinary tract infections when long-term therapy is considered necessary. This drug should only be used after eradication of the infection by other appropriate antimicrobial agents.
To reduce the development of drug-resistant bacteria and maintain the effectiveness of methenamine hippurate tablets, USP and other antibacterial drugs, methenamine hippurate tablets, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Methenamineu00a0hippurate tablets, USP are contraindicated in patients with renal insufficiency, severe hepatic insufficiency, or severe dehydration. Methenamine preparations should not be given to patients taking sulfonamides because some sulfonamides may form an insoluble precipitate with formaldehyde in the urine.

Large doses of methenamine (8 grams daily for 3 to 4 weeks) have caused bladder irritation, painful and frequent micturition, albuminuria, and gross hematuria.

Prescribingu00a0methenamine hippurate tablets,u00a0USP in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
1.u00a0 Care should be taken to maintain an acid pH of the urine, especially when treating infections due to urea-splitting organisms such as and strains of .
2.u00a0 In a few instances in one study, the serum transaminase levels were slightly elevated during treatment but returned to normal whileu00a0the patients were still takingu00a0methenamine hippurate tablets,u00a0USP. Because of this report, it is recommended that liver function studiesu00a0be performed periodically on patients taking the drug, especially those with liver dysfunction.
3.u00a0 Use in Pregnancy: In early pregnancy the safe use of methenamine hippurate tablets, USP is not established. In the last trimester,u00a0safety is suggested, but not definitely proved. No adverse effects on the fetus were seen in studies in pregnant rats and rabbits.u00a0u00a0u00a0u00a0Methenamineu00a0hippurate tablets,u00a0USP taken during pregnancy can interfere with laboratory tests of urine estriol (resulting inu00a0unmeasurably low values) when acid hydrolysis is used in the laboratory procedure. This interference is due to the presence inu00a0theu00a0urine of methenamine and/or formaldehyde. Enzymatic hydrolysis, in place of acid hydrolysis, will circumvent this problem.

Minor adverse reactions have been reported in less than 3.5% of patients treated. These reactions have included nausea, upset stomach, dysuria, and rash.
To report SUSPECTED ADVERSE REACTIONS, contact Impax Laboratories, Inc. at 1-800-934-6729 or FDA at 1-800-FDA-1088 or .

1 tablet (1 g) twice daily (morning and night) for adults and pediatric patients over 12 years of age. 1/2 to 1 tablet (0.5 to 1 g) twice daily (morning and night) for pediatric patients 6 to 12 years of age. Since the antibacterial activity of methenamine hippurate tablets, USP is greater in acid urine, restriction of alkalinizing foods and medications is desirable. If necessary, as indicated by urinary pH and clinical response, supplemental acidification of the urine should be instituted. The efficacy of therapy should be monitored by repeated urine cultures.

Methenamineu00a0hippurate tabletsu00a0USP, 1 g are supplied as peach, oval shaped compressed tablets debossed u201ccoru201d on the left and u201c139u201d on the right side of bisect on one side and other side is plain.
Methenamine hippurate tablets USP, 1 g are supplied:Bottles of 100u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0 (NDC 0115-1754-01)
Store atu00a0 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F) [See USP Controlled Room Temperature].
Dispense in well-closed, light-resistant container with child-resistant closure.

Distributedu00a0by: Impax Genericsu00a0Hayward, CA 94544n 2021-02
Rev.u00a0 12/2017

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Methenamine Hippurate (Methenamine Hippurate)

Trade Name : Methenamine Hippurate

TABLET

Delivery Process

Product information is meant for

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

Packaging and Delivery

About GNH

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Methenamine Hippurate (Methenamine Hippurate)

Trade Name : Methenamine Hippurate

TABLET

Delivery Process

Product information is meant for

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

Packaging and Delivery

About GNH

Similar Products

Desogestrel And Ethinyl Estradiol (Emoquette)

Diphenoxylate Hydrochloride And Atropine Sulfate (Diphenoxylate Hydrochloride And Atropine Sulfate)

Fluoxetine Hydrochloride (Fluoxetine)

Metoprolol Succinate (Metoprolol Succinate)

Losartan Potassium (Losartan Potassium)

Browse Our Services And Processes

Disclaimer

Browse from other international pharmaceuticals

General

US NDC

Canadian DIN

Swiss Drugs

NZ Drugs

FAQ

Can’t find what you’re looking for?

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CONTACT US

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