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Mometasone Furoate (Elocon)

Trade Name : ELOCON

Merck Sharp & Dohme Corp.

LOTION

Strength 1 mg/mL

MOMETASONE FUROATE Corticosteroid [EPC],Corticosteroid Hormone Receptor Agonists [MoA],Corticosteroid Hormone Receptor Agonists [MoA]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Mometasone Furoate (Elocon) which is also known as ELOCON and Manufactured by Merck Sharp & Dohme Corp.. It is available in strength of 1 mg/mL per ml. Read more

Mometasone Furoate (Elocon) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • ELOCON Lotion is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients 12 years of age or older.
  • ELOCON Lotion is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients u226512 years of age. ()
  • Apply a few drops of ELOCON Lotion to the affected skin areas once daily and massage lightly until it disappears.
  • Therapy should be discontinued when control is achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary .
  • Do not use ELOCON Lotion with occlusive dressings unless directed by a physician. Do not apply ELOCON Lotion in the diaper area if the patient requires diapers or plastic pants, as these garments constitute occlusive dressing.
  • ELOCON Lotion is for topical use only. It is not for oral, ophthalmic, or intravaginal use.
  • Avoid use on the face, groin, or axillae. Avoid contact with eyes. Wash hands after each application.
  • Apply a few drops to the affected skin areas once daily and massage lightly until it disappears. ()
  • Discontinue therapy when control is achieved. ()
  • If no improvement is seen within 2 weeks, reassess diagnosis. ()
  • Do not use with occlusive dressings unless directed by a physician. ()
  • Lotion, 0.1%. Each gram of ELOCON Lotion contains 1 mg of mometasone furoate in a colorless, clear to translucent lotion base.
  • Lotion, 0.1%. ()
  • ELOCON Lotion is contraindicated in those patients with a history of hypersensitivity to any of the components in the preparation.
  • ELOCON Lotion is contraindicated in those patients with a history of hypersensitivity to any of the components in the preparation. ()
  • No data
  • Reversible HPA axis suppression with the potential for glucocorticosteroid insufficiency after withdrawal of treatment, Cushing's syndrome, and hyperglycemia may occur due to systemic absorption. Patients applying a topical steroid to a large surface area or to areas under occlusion should be evaluated periodically for evidence of HPA axis suppression. Modify use should HPA axis suppression develop. (,)
  • Pediatric patients may be more susceptible to systemic toxicity. (,)
  • May increase the risk of cataracts and glaucoma. If visual symptoms occur, consider referral to an ophthalmologist. ()
  • Most common adverse reactions included are acneiform reaction, burning, itching and folliculitis. ()
  • To report SUSPECTED ADVERSE REACTIONS, contact Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., at 1-877-888-4231 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
  • No drug-drug interaction studies have been conducted with ELOCON Lotion.
  • No data
  • Topically applied ELOCON Lotion can be absorbed in sufficient amounts to produce systemic effects .
  • ELOCON (mometasone furoate) Lotion, 0.1% contains mometasone furoate for topical use. Mometasone furoate is a synthetic corticosteroid with anti-inflammatory activity.
  • Chemically, mometasone furoate is 9u03b1, 21-dichloro-11u03b2,17-dihydroxy-16u03b1-methylpregna-1,4-diene-3,20-dione 17-(2-furoate), with the empirical formula CHClO, a molecular weight of 521.4 and the following structural formula:
  • Mometasone furoate is a white to off-white powder practically insoluble in water, slightly soluble in octanol, and moderately soluble in ethyl alcohol.
  • Each gram of ELOCON Lotion, 0.1% contains 1 mg mometasone furoate in a colorless, clear to translucent lotion base of hydroxypropyl cellulose, isopropyl alcohol (40%), propylene glycol, purified water and sodium phosphate monobasic monohydrate. May also contain phosphoric acid used to adjust the pH to approximately 4.5.
  • No data
  • Long-term animal studies have not been performed to evaluate the carcinogenic potential of ELOCON Lotion. Long-term carcinogenicity studies of mometasone furoate were conducted by the inhalation route in rats and mice. In a 2-year carcinogenicity study in Sprague Dawley rats, mometasone furoate demonstrated no statistically significant increase of tumors at inhalation doses up to 67 mcg/kg (approximately 0.04 times the estimated maximum clinical topical dose from ELOCON Lotion on a mcg/m basis). In a 19-month carcinogenicity study in Swiss CD-1 mice, mometasone furoate demonstrated no statistically significant increase in the incidence of tumors at inhalation doses up to 160 mcg/kg (approximately 0.05 times the estimated maximum clinical topical dose from ELOCON Lotion on a mcg/m basis).
  • Mometasone furoate increased chromosomal aberrations in an Chinese hamster ovary cell assay, but did not increase chromosomal aberrations in an Chinese hamster lung cell assay. Mometasone furoate was not mutagenic in the Ames test or mouse lymphoma assay, and was not clastogenic in an mouse micronucleus assay, a rat bone marrow chromosomal aberration assay, or a mouse male germ-cell chromosomal aberration assay. Mometasone furoate also did not induce unscheduled DNA synthesis in rat hepatocytes.
  • In reproductive studies in rats, impairment of fertility was not produced in male or female rats by subcutaneous doses up to 15 mcg/kg (approximately 0.01 times the estimated maximum clinical topical dose from ELOCON Lotion on a mcg/m basis).
  • The safety and efficacy of ELOCON Lotion, 0.1% for the treatment of corticosteroid-responsive dermatoses was demonstrated in two vehicle-controlled trials, one in scalp psoriasis and one in seborrheic dermatitis. A total of 405 subjects (age range: 12-95 years) received ELOCON Lotion (205 subjects) or the vehicle lotion applied once daily for 21 days.
  • ELOCON Lotion is colorless, clear to translucent and supplied in 30-mL (27.5 gram) (NDC 0085-0854-01) and 60-mL (55 gram) (NDC 0085-0854-02) bottles; boxes of one.
  • Store ELOCON Lotion, 0.1% at 25u00b0C (77u00b0F); excursions permitted to 15-30u00b0C (59-86u00b0F) [see USP Controlled Room Temperature].
  • Advise the patient to read the FDA-approved patient labeling (Patient Information).
  • Inform patients of the following:
  • Distributed by: Merck Sharp & Dohme Corp., a subsidiary ofn Whitehouse Station, NJ 08889, USA
  • For patent information: www.merck.com/product/patent/home.html
  • Copyright u00a9 1989-2019 Merck Sharp & Dohme Corp., a subsidiary of n All rights reserved.
  • uspi-mk0887-lt-1907r009
  • usppi-mk0887-lt-1805r000
  • PRINCIPAL DISPLAY PANEL - 30 mL Bottle Carton
  • NDC 0085-0854-01
  • 30 mL (27.5 g)
  • Eloconn n- Lotion, 0.1%
  • For topical use only. Not forophthalmic use.
  • DO NOT USE IN EYES
  • Rx only

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