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Naftifine Hydrochloride (Naftin)

Trade Name : Naftin

Merz Pharmaceuticals, LLC

CREAM

Strength 10 mg/g

NAFTIFINE HYDROCHLORIDE Allylamine [CS],Allylamine Antifungal [EPC]

Delivery Process

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Product information is meant for

Wholesalers Suppliers Exporters Doctors MOH Tender Supplies Hospitals Brand CROs Comparator Supplies Generic Cooperate Sourcing Individual Patients Indian Institutional Buyers

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Naftifine Hydrochloride (Naftin) which is also known as Naftin and Manufactured by Merz Pharmaceuticals, LLC. It is available in strength of 10 mg/g per ml. Read more

Naftifine Hydrochloride (Naftin) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Rx ONLY
  • Naftin Cream, 1% and Naftin Gel, 1% contain the synthetic, broad-spectrum, antifungal agent naftifine hydrochloride. Naftin Cream and Gel, 1% are for topical use only.
  • Naftifine Hydrochloride is a synthetic allylamine derivative. The following data are available but their clinical significance is unknown. Naftifine hydrochloride has been shown to exhibit fungicidal activity against a broad spectrum of organisms, including and and fungistatic activity against species, including Naftin Cream and Gel, 1% have only been shown to be clinically effective against the disease entities listed in the section.
  • Although the exact mechanism of action against fungi is not known, naftifine hydrochloride appears to interfere with sterol biosynthesis by inhibiting the enzyme squalene 2, 3-epoxidase. This inhibition of enzyme activity results in decreased amounts of sterols, especially ergosterol, and a corresponding accumulation of squalene in the cells.
  • In vitro
  • in vivo
  • Following a single topical application of 1% of naftifine cream to the skin of healthy subjects, systemic absorption of naftifine was approximately 6% of the applied dose. Following single topical applications of H- labeled naftifine gel 1% to the skin of healthy subjects, up to 4.2% of the applied dose was absorbed. Naftifine and/or its metabolites are excreted via the urine and feces with a half-life of approximately two to three days.
  • Naftin Cream, 1% is indicated for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms and . Naftin Gel, 1% is indicated for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms , .
  • Naftin Cream and Gel, 1% are contraindicated in individuals who have shown hypersensitivity to any of their components.
  • Naftin Cream and Gel, 1% are for topical use only and not for ophthalmic use.
  • No data
  • During clinical trials with Naftin Cream, 1%, the incidence of adverse reactions was as follows: burning/stinging (6%), dryness (3%), erythema (2%), itching (2%), local irritation (2%). During clinical trials with Naftin Gel, 1%. the incidence of adverse reactions was as follows: burning Istinging (5.0%), itching (1.0%), erythema (0.5%), rash (0.5%), skin tenderness (0.5%).
  • A sufficient quantity of Naftin Cream, 1% should be gently massaged into the affected and surrounding skin areas once a day. A sufficient quantity of Naftin Gel, 1% should be gently massaged into the affected and surrounding skin areas twice a day, in the morning and evening. The hands should be washed after application. If no clinical improvement is seen after four weeks of treatment with Naftin Cream or Gel, 1%, the patient should be re-evaluated.
  • Naftin (naftifine hydrochloride) Cream. 1% is supplied in collapsible tubes in the following sizes:
  • Naftin (naftifine hydrochloride) Gel, 1% is supplied in collapsible tubes in the following sizes:
  • Note:
  • Store Naftin Gel, 1% at room temperature.
  • Manufactured for n u00a9 2011 Merz Pharmaceuticals Rev 4/11 5011418
  • NDC 0259-4126-90
  • NAFTINn 90g cream
  • NAFTIFINE HCl 1% CREAM
  • Rx Only
  • MERZn

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