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Nortriptyline Hydrochloride (Nortriptyline Hydrochloride)

Trade Name : Nortriptyline Hydrochloride

Pharmaceutical Associates, Inc.

SOLUTION

Strength 10 mg/5mL

NORTRIPTYLINE HYDROCHLORIDE Tricyclic Antidepressant [EPC]

Delivery Process

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Nortriptyline Hydrochloride (Nortriptyline Hydrochloride) which is also known as Nortriptyline Hydrochloride and Manufactured by Pharmaceutical Associates, Inc.. It is available in strength of 10 mg/5mL per ml. Read more

Nortriptyline Hydrochloride (Nortriptyline Hydrochloride) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Rx ONLY
  • Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of nortriptyline hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Nortriptyline hydrochloride is not approved for use in pediatric patients. (See n n n , n n n , and n n n ).n n n
  • Nortriptyline hydrochloride is 1-propanamine,3-(10,11-dihydro-5n n n -dibenzo [n n n ]cyclohepten-5-ylidene)-n n n -methyl-hydrochloride.n nn
  • The structural formula is as follows:
  • The oral solution contains nortriptyline hydrochloride equivalent to 10 mg/5 mL (38.0 u03bcmol) of the base and 4% alcohol. It also contains cherry flavor, citric acid anhydrous, purified water, sodium benzoate, and sorbitol.
  • The mechanism of mood elevation by tricyclic antidepressants is at present unknown. Nortriptyline hydrochloride is not a monoamine oxidase inhibitor. It inhibits the activity of such diverse agents as histamine, 5-hydroxytryptamine, and acetylcholine. It increases the pressor effect of norepinephrine but blocks the pressor response of phenethylamine. Studies suggest that nortriptyline hydrochloride interferes with the transport, release, and storage of catecholamines. Operant conditioning techniques in rats and pigeons suggest that nortriptyline hydrochloride has a combination of stimulant and depressant properties.
  • Nortriptyline hydrochloride oral solution USP is indicated for the relief of symptoms of depression. Endogenous depressions are more likely to be alleviated than are other depressive states.
  • No data
  • No data
  • No data
  • Note u2013
  • Arrayn- Cardiovascular
  • Arrayn- Psychiatric
  • Arrayn- Neurologic
  • Arrayn- Anticholinergic
  • Arrayn- Allergic
  • Arrayn- Hematologic
  • Arrayn- Gastrointestinal
  • Arrayn- Endocrine
  • Arrayn- Other
  • Arrayn- Withdrawal Symptoms
  • The following adverse drug reaction has been reported during post-approval use of nortriptyline hydrochloride. Because this reaction is reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate frequency.
  • Eye Disorders
  • Deaths may occur from overdosage with this class of drugs. Multiple drug ingestion (including alcohol) is common in deliberate tricyclic antidepressant overdose. As the management is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment. Signs and symptoms of toxicity develop rapidly after tricyclic antidepressant overdose; therefore, hospital monitoring is required as soon as possible.
  • Nortriptyline hydrochloride oral solution USP is not recommended for children.
  • Nortriptyline hydrochloride oral solution USP is administered orally in the form of an oral solution. Lower than usual dosages are recommended for elderly patients and adolescents. Lower dosages are also recommended for outpatients than for hospitalized patients who will be under close supervision. The physician should initiate dosage at a low level and increase it gradually, noting carefully the clinical response and any evidence of intolerance. Following remission, maintenance medication may be required for a longer period of time at the lowest dose that will maintain remission.
  • If a patient develops minor side effects, the dosage should be reduced. The drug should be discontinued promptly if adverse effects of a serious nature or allergic manifestations occur.
  • No data
  • Arrayn- Pharmaceuticaln n n Associates, Inc.n n n
  • R01/15
  • I067802
  • Nortriptyline Hydrochloride Oral Solution USPn n n (nor trip te len)n n n
  • Antidepressant Medicines, Depression and other Serious Mental Illnesses, and Suicidal Thoughts or Actions
  • Read the Medication Guide that comes with your or your family member's antidepressant medicine. This Medication Guide is only about the risk of suicidal thoughts and actions with antidepressant medicines. n n n n
  • What is the most important information I should know about antidepressant medicines, depression and other serious mental illnesses, and suicidal thoughts or actions?
  • Call a healthcare provider right away if you or your family member has any of the following symptoms, especially if they are new, worse, or worry you:
  • Visual problems
  • Only some people are at risk for these problems. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are.
  • Who should not take nortriptyline hydrochloride?
  • Do not take nortriptyline hydrochloride if you:
  • What else do I need to know about antidepressant medicines?
  • Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
  • This Medication Guide has been approved by the U.S. Food and Drug Administration.
  • Arrayn- Pharmaceuticaln n n Associates, Inc.n n n
  • MG0678400
  • R01/15
  • NDC 0121-0678-16
  • Nortriptylinen n n Hydrochloriden n n Oral Solution USPn n n
  • 10 mg/5 mL
  • Each 5 mL contains:n n n Nortriptyline hydrochloriden n n equivalent to 10 mg of base.n n n Alcohol 4%n n n
  • PHARMACIST: Provide one attachedn n n Medication Guide to each patient or caregivern n n at the time of dispensing.n n n
  • Rx ONLY
  • 16 fl oz (473 mL)
  • Arrayn- pain n n Pharmaceuticaln n n Associates, Inc.n n n

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Unit # G- 14, 15, 16, 17, Ground Floor, Prabhadevi Industrial Estate, Enterprises Industrial Premises, 408, Veer Sawarkar Road, Prabhadevi,
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