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Potassium Citrate And Citric Acid Monohydrate (Potassium Citrate And Citric Acid)

Trade Name : Potassium Citrate and Citric Acid

Pharmaceutical Associates, Inc.

SOLUTION

Strength 1100334 mg/5mLmg/5mL

POTASSIUM CITRATE; CITRIC ACID MONOHYDRATE Acidifying Activity [MoA],Calculi Dissolution Agent [EPC],Anti-coagulant [EPC],Decreased Coagulation Factor Activity [PE],Calcium Chelating Activity [MoA],Acidifying Activity [MoA],Calculi Dissolution Agent [EPC],Anti-coagulant [EPC],Decreased Coagulation Factor Activity [PE],Calcium Chelating Activity [MoA]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Potassium Citrate And Citric Acid Monohydrate (Potassium Citrate And Citric Acid) which is also known as Potassium Citrate and Citric Acid and Manufactured by Pharmaceutical Associates, Inc.. It is available in strength of 1100; 334 mg/5mL; mg/5mL per ml. Read more

Potassium Citrate And Citric Acid Monohydrate (Potassium Citrate And Citric Acid) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Rx ONLY
  • Potassium Citrate and Citric Acid Oral Solution USP is a stable and pleasant-tasting oral systemic alkalizer containing potassium citrate and citric acid in a sugar-free, non-alcoholic base.
  • Potassium Citrate and Citric Acid Oral Solution USP contains in each teaspoonful (5 mL):
  • POTASSIUM CITRATE u00a0 u00a0 u00a0 u00a0 u00a0n Monohydrateu00a0u00a01100 mg
  • CITRIC ACID u00a0 u00a0 u00a0 u00a0 u00a0n Monohydrateu00a0u00a0334 mg
  • Each mL contains 2 mEq potassium ion and is equivalent to 2 mEq bicarbonate (HCOn n n ).n nn
  • Inactive Ingredients: FD&C Red No. 40, flavoring, polyethylene glycol, propylene glycol, purified water, sodium benzoate, and sorbitol solution.
  • Potassium citrate is absorbed and metabolized to potassium bicarbonate, thus acting as a systemic alkalizer. The effects are essentially those of chlorides before absorption and those of bicarbonates subsequently. Oxidation is virtually complete so that less than 5% of the potassium citrate is excreted in the urine unchanged.
  • Potassium Citrate and Citric Acid Oral Solution USP is an effective alkalinizing agent useful in those conditions where long-term maintenance of an alkaline urine is desirable, such as in patients with uric acid and cystine calculi of the urinary tract, especially when the administration of sodium salts is undesirable or contraindicated. In addition, it is a valuable adjuvant when administered with uricosuric agents in gout therapy, since urates tend to crystallize out of an acid urine. It is also effective in correcting the acidosis of certain renal tubular disorders where the administration of potassium citrate may be preferable. This product is highly concentrated, and when administered after meals and before bedtime, allows one to maintain an alkaline urinary pH around the clock, usually without the necessity of a 2 A.M. dose. This product alkalinizes the urine without producing a systemic alkalosis in recommended dosage. It is highly palatable, pleasant tasting and tolerable, even when administered for long periods. Potassium citrate does not neutralize the gastric juice or disturb digestion.
  • Severe renal impairment with oliguria or azotemia, untreated Addison's disease, adynamia episodica hereditaria, acute dehydration, heat cramps, anuria, severe myocardial damage, and hyperkalemia from any cause.
  • Large doses may cause hyperkalemia and alkalosis, especially in the presence of renal disease. Concurrent administration of potassium-containing medication, potassium-sparing diuretics, angiotensin-converting enzyme (ACE) inhibitors, or cardiac glycosides may lead to toxicity.
  • Should be used with caution by patients with low urinary output unless under the supervision of a physician. As with all liquids containing a high concentration of potassium, patients should be directed to dilute adequately with water to minimize the possibility of gastrointestinal injury associated with the oral ingestion of concentrated potassium salt preparations; and preferably, to take each dose after meals to avoid saline laxative effect.
  • Potassium Citrate and Citric Acid Oral Solution USP is generally well tolerated without any unpleasant side effects when given in recommended doses to patients with normal renal function and urinary output. However, as with any alkalinizing agent, caution must be used in certain patients with abnormal renal mechanisms to avoid development of hyperkalemia or alkalosis. Potassium intoxication causes listlessness, weakness, mental confusion, tingling of extremities, and other symptoms associated with a high concentration of potassium in the serum. Periodic determinations of serum electrolytes should be carried out in those patients with renal disease in order to avoid these complications. Hyperkalemia may exhibit the following electrocardiographic abnormalities: Disappearance of the P wave, widening and slurring of QRS complex, changes of the S-T segment, tall peaked T waves, etc.
  • The administration of oral potassium salts to persons with normal excretory mechanisms for potassium rarely causes serious hyperkalemia. However, if excretory mechanisms are impaired, hyperkalemia can result (see n n n and n n n ). Hyperkalemia, when detected, must be treated immediately because lethal levels can be reached in a few hours.n nn
  • Should hyperkalemia occur, treatment measures include the following: (1) Elimination of foods or medications containing potassium. (2) The intravenous administration of 300 to 500 mL/hr of dextrose solution (10 to 25%), containing 10 units of insulin/20 gm dextrose. (3) The use of exchange resins, hemodialysis, or peritoneal dialysis. In treating hyperkalemia, it should be recalled that in patients who have been stabilized on digitalis, too rapid a lowering of the plasma potassium concentration can produce digitalis toxicity.
  • Potassium Citrate and Citric Acid Oral Solution USP should be taken diluted in water according to directions, followed by additional water, if desired. Palatability is enhanced if chilled before taking.
  • Potassium Citrate and Citric Acid Oral Solution USP (clear pink to red colored; berry-citrus flavored) is supplied in the following oral dosage form:
  • NDC 0121-0676-16: 16 fl oz (473 mL) bottle
  • Keep tightly closed. Store at controlled room temperature, 20u00b0-25u00b0C (68u00b0-77u00b0F). Protect from excessive heat and freezing.
  • Pharmaceuticaln n n Associates, Inc.n n n
  • R03/17
  • NDC 0121-0676-16
  • Potassium Citraten n n and Citric Acidn n n Oral Solution USPn n n 1100 mg/334 mg per 5 mLn n n
  • A SUGAR-FREE SYSTEMIC ALKALIZER
  • Each teaspoonful (5 mL) contains:n n n Potassium Citrate Monohydrateu2026..1100 mgn n n Citric Acid Monohydrateu2026..334 mgn nn
  • Each mL contains 2 mEq Potassium Ion, and isn n n equivalent to 2 mEq Bicarbonate (HCO3).n nn
  • Rx ONLY
  • 16 fl oz (473 mL)
  • Arrayn- Array
  • INDICATIONS AND USAGE:u00a0
  • SEE ACCOMPANYING LITERATURE
  • DOSAGE AND ADMINISTRATION:
  • Usual Adult Dosage: n- DILUTED
  • SHAKE WELL BEFORE USING.
  • STORAGE:u00a0
  • Dispense in a tight, light-resistance containern n n with a child-resistant closure.n nn
  • L06761600n- R08/14
  • Array
  • Arrayn- Array

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