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Quinapril Hydrochloride (Accupril)

Trade Name : Accupril

Parke-Davis Div of Pfizer Inc

TABLET, FILM COATED

Strength 5 mg/1

QUINAPRIL HYDROCHLORIDE Angiotensin Converting Enzyme Inhibitor [EPC],Angiotensin-converting Enzyme Inhibitors [MoA]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Quinapril Hydrochloride (Accupril) which is also known as Accupril and Manufactured by Parke-Davis Div of Pfizer Inc. It is available in strength of 5 mg/1 per ml. Read more

Quinapril Hydrochloride (Accupril) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
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  • ACCUPRIL (quinapril hydrochloride) is the hydrochloride salt of quinapril, the ethyl ester of a non-sulfhydryl, angiotensin-converting enzyme (ACE) inhibitor, quinaprilat.
  • Quinapril hydrochloride is chemically described as [3S-[2[R*(R*)], 3R*]]-2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, monohydrochloride. Its empirical formula is CHNO u2219HCl and its structural formula is:
  • Quinapril hydrochloride is a white to off-white amorphous powder that is freely soluble in aqueous solvents.
  • ACCUPRIL tablets contain 5 mg, 10 mg, 20 mg, or 40 mg of quinapril for oral administration. Each tablet also contains candelilla wax, crospovidone, gelatin, lactose, magnesium carbonate, magnesium stearate, synthetic red iron oxide, and titanium dioxide.
  • No data
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  • ACCUPRIL is contraindicated in patients who are hypersensitive to this product and in patients with a history of angioedema related to previous treatment with an ACE inhibitor.
  • ACCUPRIL is contraindicated in combination with a neprilysin inhibitor (e.g., sacubitril). Do not administer ACCUPRIL within 36 hours of switching to or from sacubitril/valsartan, a neprilysin inhibitor (see and ).
  • Do not co-administer ACCUPRIL with aliskiren in patients with diabetes.
  • Presumably because ACE inhibitors affect the metabolism of eicosanoids and polypeptides, including endogenous bradykinin, patients receiving ACE inhibitors (including ) may be subject to a variety of adverse reactions, some of them serious.
  • No data
  • No data
  • Doses of 1440 to 4280 mg/kg of quinapril cause significant lethality in mice and rats.
  • No specific information is available on the treatment of overdosage with quinapril. The most likely clinical manifestation would be symptoms attributable to severe hypotension.
  • Laboratory determinations of serum levels of quinapril and its metabolites are not widely available, and such determinations have, in any event, no established role in the management of quinapril overdose.
  • No data are available to suggest physiological maneuvers (eg, maneuvers to change pH of the urine) that might accelerate elimination of quinapril and its metabolites.
  • Hemodialysis and peritoneal dialysis have little effect on the elimination of quinapril and quinaprilat. Angiotensin II could presumably serve as a specific antagonist-antidote in the setting of quinapril overdose, but angiotensin II is essentially unavailable outside of scattered research facilities. Because the hypotensive effect of quinapril is achieved through vasodilation and effective hypovolemia, it is reasonable to treat quinapril overdose by infusion of normal saline solution.
  • No data
  • ACCUPRIL tablets are supplied as follows:
  • 5-mg tablets:
  • 10-mg tablets:
  • 20-mg tablets:
  • 40-mg tablets:
  • Dispense in well-closed containers as defined in the USP.
  • Store at controlled room temperature 15u00bau201330u00baC (59u00bau201386u00baF).
  • Protect from light.
  • LAB-0215-16.0
  • July 2017
  • Pfizer
  • NDC 0071-0527-23
  • Accupril
  • 5 mg*
  • ttttttt90 Tabletsn n
  • Accupriln
  • 5 mg
  • DISTRIBUTED BY:PARKE-DAVISDIV OF PFIZER INC, NY, NY 10017MADE IN IRELAND
  • UNIT DOSE
  • Pfizer
  • NDC 0071-0527-40
  • Accupril n
  • 5 mg*
  • For in-institution use only
  • 100 Tabletsn n
  • Pfizer
  • NDC 0071-0530-23
  • Accupriln
  • 10 mg*
  • ttttttt90 Tabletsn n
  • Accupriln
  • 10 mg
  • DISTRIBUTED BY:PARKE-DAVISDIV OF PFIZER INC, NY, NY 10017MADE IN IRELAND
  • UNIT DOSE
  • Pfizer
  • NDC 0071-0530-40
  • Accupril n
  • 10 mg*
  • For in-institution use only
  • 100 Tabletsn n
  • Pfizer
  • NDC 0071-0532-23
  • Accupriln
  • 20 mg*
  • ttttttt90 Tabletsn n
  • Accupriln
  • 20 mg
  • DISTRIBUTED BY:PARKE-DAVISDIV OF PFIZER INC, NY, NY 10017MADE IN IRELAND
  • UNIT DOSE
  • Pfizer
  • NDC 0071-0532-40
  • Accupril n
  • 20 mg*
  • For in-institution use only
  • 100 Tabletsn n
  • Pfizer
  • NDC 0071-0535-23
  • Accupriln
  • 40 mg*
  • ttttttt90 Tabletsn n

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