Tretinoin (Retin-A)

Trade Name : Retin-A

Bausch Health US LLC

CREAM

Strength 0.25 mg/g

TRETINOIN Retinoid [EPC],Retinoids [CS]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Tretinoin (Retin-A) which is also known as Retin-A and Manufactured by Bausch Health US LLC. It is available in strength of 0.25 mg/g per ml. Read more

Tretinoin (Retin-A) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials. Click to know price. Read less

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No data

For Topical Use Only

RETIN-A Gel and Cream, containing tretinoin, are used for the topical treatment of acne vulgaris. RETIN-A Gel contains tretinoin (retinoic acid, vitamin A acid) in either of two strengths, 0.025% or 0.01% by weight, in a gel vehicle of butylated hydroxytoluene, hydroxypropyl cellulose and alcohol (denatured withbutyl alcohol and brucine sulfate) 90% w/w. RETIN-A (tretinoin) Cream contains tretinoin in one of three strengths, 0.1%, 0.05%, or 0.025% by weight, in a hydrophilic cream vehicle of stearic acid, isopropyl myristate, polyoxyl 40 stearate, stearyl alcohol, xanthan gum, sorbic acid, butylated hydroxytoluene, and purified water. Chemically, tretinoin isretinoic acid and has the following structure:

Although the exact mode of action of tretinoin is unknown, current evidence suggests that topical tretinoin decreases cohesiveness of follicular epithelial cells with decreased microcomedo formation. Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells causing extrusion of the comedones.

RETIN-A is indicated for topical application in the treatment of acne vulgaris. The safety and efficacy of the long-term use of this product in the treatment of other disorders have not been established.

Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

No data

The skin of certain sensitive individuals may become excessively red, edematous, blistered, or crusted. If these effects occur, the medication should either be discontinued until the integrity of the skin is restored, or the medication should be adjusted to a level the patient can tolerate. True contact allergy to topical tretinoin is rarely encountered. Temporary hyper- or hypopigmentation has been reported with repeated application of RETIN-A. Some individuals have been reported to have heightened susceptibility to sunlight while under treatment with RETIN-A. To date, all adverse effects of RETIN-A have been reversible upon discontinuance of therapy (see ).
To report SUSPECTED ADVERSE REACTIONS, contact Bausch Health US, LLC at 1-800-321-4576 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

If medication is applied excessively, no more rapid or better results will be obtained and marked redness, peeling, or discomfort may occur. Oral ingestion of the drug may lead to the same side effects as those associated with excessive oral intake of Vitamin A.

RETIN-A Gel or Cream should be applied once a day, before retiring, to the skin where acne lesions appear, using enough to cover the entire affected area lightly. Gel: Excessive application results in u201cpillingu201d of the gel, which minimizes the likelihood of overapplication by the patient.
Application may cause a transitory feeling of warmth or slight stinging. In cases where it has been necessary to temporarily discontinue therapy or to reduce the frequency of application, therapy may be resumed or frequency of application increased when the patients become able to tolerate the treatment.
Alterations of vehicle, drug concentration, or dose frequency should be closely monitored by careful observation of the clinical therapeutic response and skin tolerance.
During the early weeks of therapy, anexacerbation of inflammatory lesions may occur. This is due to the action of the medication on deep, previously unseen lesions and should not be considered a reason to discontinue therapy.
Therapeutic results should be noticed after 2 to 3 weeks but more than 6 weeks of therapy may be required before definite beneficial effects are seen.
Once the acne lesions have responded satisfactorily, it may be possible to maintain the improvement with less frequent applications, or other dosage forms.
Patients treated with RETIN-A (tretinoin) acne treatment may use cosmetics, but the area to be treated should be cleansed thoroughly before the medication is appliedsee n

RETIN-A (tretinoin) is supplied as:
RETIN-A Gel, 0.025% and 0.01%: store below 86u00b0F. RETIN-A Cream, 0.1%, 0.05%, and 0.025%: store below 80u00b0F.

Manufactured for:
Manufactured by:
Retin-A is a trademark of Bausch Health Companies Inc. or its affiliates.
u00a9 2019 Bausch Health Companies Inc. or its affiliates
9440904n Revised: 09/2019

RETIN-An n- (tretinoin)
Cream u2022 Gel
For Topical Use Onlyn PATIENT INSTRUCTIONS
Acne Treatment
IMPORTANT
Read Directions Carefully Before Using
THIS LEAFLET TELLS YOU ABOUT RETIN-A (TRETINOIN) ACNE TREATMENT AS PRESCRIBED BY YOUR PHYSICIAN. THIS PRODUCT IS TO BE USED ONLY ACCORDING TO YOUR DOCTORu2019S INSTRUCTIONS, AND IT SHOULD NOT BE APPLIED TO OTHER AREAS OF THE BODY OR TO OTHER GROWTHS OR LESIONS. THE LONG-TERM SAFETY AND EFFECTIVENESS OF THIS PRODUCT IN OTHER DISORDERS HAVE NOT BEEN EVALUATED. IF YOU HAVE ANY QUESTIONS, BE SURE TO ASK YOUR DOCTOR.
WARNINGS
RETIN-A GELS ARE FLAMMABLE. AVOID FIRE, FLAME OR SMOKING DURING USE.
PRECAUTIONS
The effects of the sun on your skin.
Laboratory findings. n- When laboratory mice are exposed to artificial sunlight, they often develop skin tumors. These sunlight-induced tumors may appear more quickly and in greater number if the mouse is also topically treated with the active ingredient in RETIN-A, tretinoin. In some studies, under different conditions, however, when mice treated with tretinoin were exposed to artificial sunlight, the incidence and rate of development of skin tumors was reduced. There is no evidence to date that tretinoin alone will cause the development of skin tumors in either laboratory animals or humans. However, investigations in this area are continuing.
Use caution in the sun. n- any time you are outside
Avoid excessive exposure to wind or cold.
Possible problems.
There have been reports that, in some patients, areas treated with RETIN-A developed a temporary increase or decrease in the amount of skin pigment (color) present. The pigment in these areas returned to normal either when the skin was allowed to adjust to RETIN-A or therapy was discontinued.
Use other medications only on your physicianu2019s advice.
Do not use other medications with RETIN-A which are not recommended by your doctor. The medications you have used in the past might cause unnecessary redness or peeling.
If you are pregnant, think you are pregnant or are nursing an infant:
AND WHILE YOUu2019RE ON RETIN-A THERAPY
Use a mild, non-medicated soap. Avoid frequent washings and harsh scrubbing.
HOW TO USE RETIN-A (TRETINOIN)
To get the best results with RETIN-A therapy, it is necessary to use it properly. Forget about the instructions given for other products and the advice of friends. Just stick to the special plan your doctor has laid out for you and be patient. Remember, when RETIN-A ismany users see improvement by 12 weeks. AGAIN, FOLLOW INSTRUCTIONS u2013 BE PATIENT u2013 DONu2019T START AND STOP THERAPY ON YOUR OWN u2013 IF YOU HAVE QUESTIONS, ASK YOUR DOCTOR.
To help you use the medication correctly, keep these simple instructions in mind.
WHAT TO EXPECT WITH YOUR NEW TREATMENT
RETIN-A works deep inside your skin and this takes time. You cannot make RETIN-A work any faster by applying more than one dose each day, but an excess amount of RETIN-A may irritate your skin. Be patient.
There may be some discomfort or peeling during the early days of treatment. Some patients also notice that their skin begins to take on a blush.
These reactions do not happen to everyone. If they do, it is just your skin adjusting to RETIN-A and this usually subsides within 2 to 4 weeks. These reactions can usually be minimized by following instructions carefully. Should the effects become excessively troublesome, consult your doctor.
BY 3 TO 6 WEEKS, some patients notice an appearance of new blemishes (papules and pustules). At this stage it isusing RETIN-A.
If RETIN-A is going to have a beneficial effect for you, you should notice a continued improvement in your appearance after 6 to 12 weeks of therapy. Donu2019t be discouraged if you see no immediate improvement. Donu2019t stop treatment at the first signs of improvement.
Once your acne is under control you should continue regular application of RETIN-A until your physician instructs otherwise.
IF YOU HAVE QUESTIONS
All questions of a medical nature should be taken up with your doctor. For more information about RETIN-A (tretinoin), call our toll-free number: 800-321-4576. Call between 9:00 a.m. and 3:00 p.m. Eastern Time, Monday through Friday.n n RETIN-A Gel, 0.025% and 0.01%: store below 86u00b0F. RETIN-A Cream, 0.1%, 0.05%, and 0.025%: store below 80u00b0F.
Manufactured for:
Manufactured by:
Retin-A is a trademark of Bausch Health Companies Inc. or its affiliates.
u00a9 2019 Bausch Health Companies Inc. or its affiliates
9440904n Revised: 09/2019

NDC
Retin-A Creamn- (tretinoin) 0.025%
Each gram contains:
For Topical Use Onlyu00a0u00a0u00a0n- Rx onlyn- Usual Dosage: See package insert.n- Store below 80u00b0F.n- WARNING: Keep out of reach of children.
Net Wt. 45 g

NDC
Retin-A Creamn- (tretinoin) 0.05%
Each gram contains:
For Topical Use Onlyu00a0u00a0u00a0n- Rx onlyn- Usual Dosage: See package insert.n- Store below 80u00b0F.n- WARNING: Keep out of reach of children.
Net Wt. 45 g

NDC
Retin-A Creamn- (tretinoin) 0.1%
Each gram contains:
For Topical Use Onlyu00a0u00a0u00a0n- Rx onlyn- Usual Dosage: See package insert.n- Store below 80u00b0F.n- WARNING: Keep out of reach of children.
Net Wt. 45 g

NDC
Retin-A Geln- (tretinoin) 0.01%
Each gram contains:n- tert-
For Topical Use Onlyu00a0u00a0u00a0n- Rx onlyn- Usual Dosage: See package insert.n- Store below 86u00b0F.n- WARNING: Keep out of reach of children.
Net Wt. 45 g

NDC
Retin-A Geln- (tretinoin) 0.025%
Each gram containsn- tert-
For Topical Use Onlyu00a0u00a0u00a0n- Rx onlyn- Usual Dosage: See package insert.n- Store below 86u00b0F.n- WARNING: Keep out of reach of children.
Net Wt. 45 g

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Tretinoin (Retin-A)

Trade Name : Retin-A

CREAM

Delivery Process

Product information is meant for

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

Packaging and Delivery

About GNH

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Tretinoin (Retin-A)

Trade Name : Retin-A

CREAM

Delivery Process

Product information is meant for

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

Packaging and Delivery

About GNH

Similar Products

Desogestrel And Ethinyl Estradiol (Emoquette)

Diphenoxylate Hydrochloride And Atropine Sulfate (Diphenoxylate Hydrochloride And Atropine Sulfate)

Fluoxetine Hydrochloride (Fluoxetine)

Metoprolol Succinate (Metoprolol Succinate)

Losartan Potassium (Losartan Potassium)

Browse Our Services And Processes

Disclaimer

Browse from other international pharmaceuticals

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Swiss Drugs

NZ Drugs

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