Product image of Valganciclovir Sup (Valganciclovir Hydrochloride) 50mg/ml X 100ml SOLUTION supplied by GNH India

Valganciclovir Sup

Active Ingredient:
Valganciclovir Hydrochloride
Form:
SOLUTION
Origin:
India

Valganciclovir Sup (Valganciclovir Hydrochloride SOLUTION) 50mg/ml X 100ml

Valganciclovir, the active ingredient in Valganciclovir Sup, is an antiviral presented as a 50mg/mL solution for oral use. It is used to treat cytomegalovirus (CMV) infections in immunocompromised patients, such as those with AIDS or those who have undergone organ transplants.

GNH India supplies Valganciclovir Sup as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and transplant centers worldwide.

Strength

50mg/ml X 100ml

Pack Size

1s

Storage

Below 25°C

Manufacturer / TM Owner

AUROBINDO PHARMA, LTD U.S

1
Pack/s
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Indications & Clinical Uses

Valganciclovir Sup is an antiviral medication used to manage cytomegalovirus (CMV) infections.

  • Cytomegalovirus (CMV) infection in immunocompromised patients: Helps control the virus in individuals with weakened immune systems.
  • CMV retinitis in patients with AIDS: Prevents vision loss by treating CMV-related eye infections.
  • Prevention of CMV disease in transplant recipients: Reduces the risk of CMV infection in patients who have received an organ transplant from a CMV-infected donor.

How It Works

  • After oral absorption, valganciclovir is rapidly converted to ganciclovir, which is phosphorylated to ganciclovir triphosphate. This metabolite competitively inhibits viral DNA polymerase, terminating viral DNA chain elongation.

Side Effects

Valganciclovir Sup may cause several side effects, ranging from common to serious.

Common Side Effects

  • Nausea: A frequent gastrointestinal side effect.
  • Diarrhea: Another common gastrointestinal issue.
  • Fatigue: General tiredness or weakness.
  • Headache: Mild to moderate headaches.
  • Fever: Elevated body temperature.
  • Changes in blood cell counts: May affect red or white blood cells.

Serious or Rare Side Effects

  • Anemia: Low red blood cell count.
  • Neutropenia: Low white blood cell count.
  • Thrombocytopenia: Low platelet count.
  • Sepsis: Severe infection.
  • Hypersensitivity reactions: Allergic reactions.
  • Visual impairment: Changes in vision.

Precautions & Warnings

Valganciclovir Sup should be used with caution and under medical supervision.

  • Pregnancy: Avoid use unless directed by a doctor due to potential risks to the fetus.
  • Breastfeeding: Consult a healthcare provider before use.
  • Kidney problems: Monitor kidney function regularly.
  • Blood cell counts: Regular blood tests may be required.
  • Avoid sharing medication: Do not share with others, even if they have similar symptoms.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Valganciclovir Sup may interact with other medications, potentially affecting its efficacy or safety.

Major Interactions (Avoid)

  • Immunosuppressants: May increase the risk of infections.
  • Other antiviral drugs: May cause additive side effects.
  • Myelosuppressive agents: May increase the risk of blood cell abnormalities.

Moderate Interactions (Monitor Closely)

  • Alcohol: May increase the risk of side effects.
  • Certain foods: May affect medication absorption.
  • Probenecid: May increase valganciclovir levels in the blood.

Frequently Asked Questions

Valganciclovir Sup is used to treat cytomegalovirus (CMV) infections in immunocompromised patients, such as those with AIDS or those who have undergone organ transplants. It helps control the virus and prevent complications like CMV retinitis, which can lead to vision loss.

Valganciclovir is rapidly converted to ganciclovir after oral absorption. Ganciclovir is then phosphorylated to ganciclovir triphosphate, which competitively inhibits viral DNA polymerase, terminating viral DNA chain elongation and preventing the virus from multiplying.

The dosage of Valganciclovir Sup is determined by a healthcare provider based on the patient's condition, weight, and response to treatment. It is important to follow the prescribed dosage and administration instructions provided by your healthcare professional.

Valganciclovir Sup should be avoided during pregnancy unless directed by a doctor, as it can cause harm to a developing fetus. Breastfeeding individuals should consult a healthcare provider before using this medication to discuss potential risks and benefits.

To order Valganciclovir Sup from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.

Valganciclovir Sup is specifically designed to treat CMV infections and is often preferred for its convenience as an oral solution. It is converted to ganciclovir in the body, which is effective against CMV. Other antiviral medications may be used for different types of viral infections and may have different mechanisms of action.

Valganciclovir Sup should be stored below 25°C, in the original pack, and protected from moisture. Keep the medication out of reach of children and away from direct sunlight. Follow the storage instructions provided by your healthcare professional to maintain the medication's potency.

Valganciclovir Sup is administered orally as a solution. The medication should be taken as directed by your healthcare provider, typically with a meal to enhance absorption. Follow the prescribed dosage and administration instructions carefully.

The most serious risks associated with Valganciclovir Sup include severe infections like sepsis, blood cell abnormalities such as anemia, neutropenia, and thrombocytopenia, and hypersensitivity reactions. Regular monitoring and blood tests may be required to manage these risks.

Valganciclovir Sup should not be used by individuals who are allergic to valganciclovir or ganciclovir. It should be used with caution in pregnant women, breastfeeding individuals, and those with kidney problems. Always consult a healthcare provider before starting this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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