Veltassa-AU (Patiromer Sachets) 16.8g

VELTASSA is used in the management of hyperkalemia, a condition characterized by elevated potassium levels in the blood. It is particularly useful in patients who are at risk of developing hyperkalemia due to various underlying conditions or treatments.

• Hyperkalemia: Reduces serum potassium levels in patients with hyperkalemia.
• Chronic Kidney Disease: Helps manage potassium levels in patients with chronic kidney disease who are at risk of hyperkalemia.
• Heart Failure: Useful in patients with heart failure who are prone to developing hyperkalemia due to medications or underlying conditions.

• VELTASSA works by binding potassium in the gastrointestinal tract and exchanging it for calcium. This process increases fecal potassium excretion and lowers serum potassium levels, thereby helping to manage hyperkalemia. The active ingredient, patiromer, is a non-absorbed polymer that selectively binds potassium in the lumen of the gastrointestinal tract.

VELTASSA may cause various side effects, ranging from common to serious. It is important to be aware of these potential effects when using the medication.

Common Side Effects

• Diarrhea: May occur due to the binding action of patiromer in the gastrointestinal tract.
• Constipation: Can result from the same mechanism that causes diarrhea.
• Abdominal Pain: Some patients may experience mild to moderate abdominal discomfort.
• Nausea: May occur as a gastrointestinal side effect.

Serious or Rare Side Effects

• Hypomagnesemia: Prolonged use may lead to low magnesium levels in the blood.
• Hypercalcemia: Due to the exchange of potassium for calcium in the gastrointestinal tract.
• Bowel Obstruction: Rare but possible, especially in patients with pre-existing bowel issues.
• Allergic Reactions: Although rare, some patients may experience allergic reactions to the medication.

VELTASSA should be used with caution and under the supervision of a healthcare professional. Certain precautions and warnings should be considered to ensure safe and effective use.

• Consult Healthcare Professional: Inform your healthcare professional about all medications you are taking, including over-the-counter drugs and supplements.
• Monitor Potassium Levels: Regular monitoring of potassium levels is essential to avoid hyperkalemia or hypokalemia.
• Bowel Issues: Patients with a history of bowel obstruction or severe constipation should use VELTASSA with caution.
• Pregnancy and Breastfeeding: The safety of VELTASSA during pregnancy and breastfeeding has not been established; consult your healthcare professional.
• Store below 25°C: Keep in the original pack, protect from moisture.

VELTASSA may interact with other medications, which can affect its efficacy and safety. It is important to be aware of these interactions to avoid potential complications.

Major Interactions (Avoid)

• Cationic Drugs: Avoid concomitant use with other cationic drugs, as they may bind to patiromer and reduce their effectiveness.
• Digoxin: Concomitant use may increase digoxin levels, leading to potential toxicity.

Moderate Interactions (Monitor Closely)

• Antibiotic Drugs: Monitor closely when used with certain antibiotics, as patiromer may affect their absorption.
• Antifungal Drugs: Regular monitoring is advised when used with antifungal medications to ensure effectiveness.