Product image of Vemlidy 25 (Tenofovir Alafenamide) 25mg Tablet supplied by GNH India

Vemlidy 25

Active Ingredient:
Tenofovir Alafenamide
Form:
Tablet
Brand:
VEMLIDY
Origin:
Switzerland

Vemlidy 25 (Tenofovir Alafenamide Tablet) 25mg

Tenofovir alafenamide, the active ingredient in Vemlidy 25, is a nucleotide reverse transcriptase inhibitor presented as a 25mg tablet for oral use. It is used to treat chronic hepatitis B infection in adults with stable liver disease.

GNH India supplies Vemlidy 25 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

25mg

Pack Size

30s

Storage

Ambient

Manufacturer / TM Owner

Gilead Sciences

1
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Indications & Clinical Uses

Vemlidy 25 is an antiviral medication used to manage chronic hepatitis B infection. It is specifically indicated for adults with stable liver disease.

  • Chronic hepatitis B infection: Controls the infection by inhibiting the virus's ability to replicate, reducing viral load and improving liver function.

How It Works

  • Tenofovir alafenamide is a prodrug that is converted intracellularly to tenofovir diphosphate. This active metabolite inhibits hepatitis B virus DNA polymerase, leading to chain termination of viral DNA synthesis and effectively reducing viral replication.

Side Effects

Vemlidy 25 may cause side effects, ranging from common to serious or rare.

Common Side Effects

  • Headache
  • Fatigue
  • Abdominal pain
  • Nausea
  • Dizziness
  • Diarrhea

Serious or Rare Side Effects

  • Renal impairment
  • Lactic acidosis
  • Hepatic decompensation
  • Severe acute exacerbation of hepatitis B
  • Bone density loss

Precautions & Warnings

Vemlidy 25 should be used with caution and under medical supervision. Important precautions include:

  • Renal impairment: Dose adjustment may be necessary in patients with renal impairment.
  • Hepatic decompensation: Monitor liver function regularly.
  • Bone density loss: Regular bone density monitoring is recommended.
  • Pregnancy: Consult a healthcare provider before use during pregnancy.
  • Lactation: Consult a healthcare provider before use while breastfeeding.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Vemlidy 25 may interact with other medications, requiring careful monitoring or dose adjustment.

Major Interactions (Avoid)

  • Didanosine: Increased risk of adverse renal and bone effects.
  • Other medications containing tenofovir disoproxil fumarate: Increased risk of toxicity.

Moderate Interactions (Monitor Closely)

  • Antacids containing aluminum or magnesium: May reduce the absorption of tenofovir alafenamide.
  • Drugs that affect renal function: May increase the risk of renal impairment.

Frequently Asked Questions

Vemlidy 25 is used to treat chronic hepatitis B infection in adults with stable liver disease. It helps control the infection by inhibiting the virus's ability to replicate, thereby reducing viral load and improving liver function.

Tenofovir alafenamide is a prodrug that is converted intracellularly to tenofovir diphosphate. This active metabolite inhibits hepatitis B virus DNA polymerase, leading to chain termination of viral DNA synthesis and effectively reducing viral replication.

The usual dose of Vemlidy 25 is one tablet taken once daily with food. The duration of treatment is determined by the prescribing healthcare provider based on individual patient response and medical history.

The safety of Vemlidy 25 during pregnancy or breastfeeding has not been fully established. Consult a healthcare provider before use during pregnancy or while breastfeeding to weigh the benefits and potential risks.

To order Vemlidy 25 from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then reply with pricing, availability, shipping, and the import paperwork.

Vemlidy 25 is a newer generation antiviral medication that offers improved efficacy and a better safety profile compared to older treatments like tenofovir disoproxil fumarate. It is specifically designed to have lower toxicity to the kidneys and bones.

Vemlidy 25 should be stored below 25°C, kept in the original pack, and protected from moisture. Ensure the medication is stored out of reach of children and pets.

Vemlidy 25 is administered orally, with one tablet taken once daily with food. It is important to follow the dosing instructions provided by the healthcare provider.

The most serious risks associated with Vemlidy 25 include renal impairment, lactic acidosis, hepatic decompensation, severe acute exacerbation of hepatitis B, and bone density loss. Regular monitoring and medical supervision are essential.

Vemlidy 25 should not be used by individuals with a known hypersensitivity to tenofovir alafenamide or any of the excipients in the formulation. It should be used with caution in patients with renal impairment or bone density issues.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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