Product image of Vivotif (Salmonella Typhi, Strain Ty21a (Live, Attenuated)) supplied by GNH India

Vivotif

Active Ingredient:
Salmonella Typhi, Strain Ty21a (Live, Attenuated)
Origin:
EU

Vivotif (Salmonella Typhi, Strain Ty21a (Live, Attenuated))

Vivotif is an oral typhoid vaccine containing the live, attenuated Salmonella Typhi strain Ty21a. It helps protect against typhoid fever caused by Salmonella Typhi bacteria. This vaccine is taken by mouth and is designed for travelers to high-risk areas. Suitable for adults and children aged 6 years and older.

Manufacturer / TM Owner

Bavarian Nordic A/S

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Indications & Clinical Uses

  • Vivotif is used to prevent typhoid fever, a serious bacterial infection spread through contaminated food and water. It is recommended for travelers visiting regions where typhoid is common, such as parts of Asia, Africa, and Latin America. The vaccine works by stimulating the body’s immune system to recognize and fight the Salmonella Typhi bacteria. It is not a treatment for active typhoid infection but helps reduce the risk of contracting the disease. Consult a healthcare provider to determine if this vaccine is appropriate for your travel plans.

Side Effects

  • Vivotif helps the body build immunity against Salmonella Typhi without causing typhoid fever. Most people tolerate the vaccine well, with common effects including mild stomach upset or low-grade fever. Some may experience mild headache or fatigue after vaccination. These effects are generally short-lived and resolve on their own. The vaccine does not provide immediate protection; it is important to complete the full vaccination course before potential exposure.

Precautions & Warnings

  • Vivotif should not be taken if you have a weakened immune system due to illness or medication. Avoid the vaccine if you have a fever or severe illness at the time of vaccination. Tell your healthcare provider about any allergies, especially to antibiotics like neomycin or polymyxin B, as these may be present in trace amounts. Keep the vaccine capsules refrigerated until use and take them exactly as directed. Do not open or crush the capsules.

Avoid Interactions

  • Vivotif may interact with certain medications, including antibiotics and immunosuppressants, which can reduce its effectiveness. Avoid taking the vaccine if you are currently on antibiotics, as they may interfere with the live bacterial components. Do not take antimalarial drugs like chloroquine or mefloquine within 3 days before or after vaccination, as they may reduce the vaccine’s efficacy. Consult your healthcare provider about any medications or supplements you are taking before vaccination.

Frequently Asked Questions

Complete the full vaccination course at least 1 week before potential exposure to Salmonella Typhi.

Yes, Vivotif is approved for adults and children aged 6 years and older.

Vivotif protects against typhoid fever caused by Salmonella Typhi but not other Salmonella strains.

Follow the vaccination schedule as closely as possible. Contact your healthcare provider if you miss a dose.

Consult your healthcare provider before vaccination if you are pregnant or breastfeeding.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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