Xalipat 100mg (Oxaliplatin) 100mg

Xalipat 100mg is a prescription antineoplastic medication containing the active ingredient oxaliplatin, which belongs to the platinum-based drug class. It is administered intravenously to inhibit cancer cell replication by cross-linking DNA strands, thereby preventing DNA synthesis and transcription. This medication is primarily utilized in oncology regimens to treat specific types of colorectal cancers under strict medical supervision.

Strength

100mg

Pack Size

Storage

15-25°

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Indications & Clinical Uses

Xalipat 100mg is indicated for the treatment of advanced colorectal cancer, often in combination with other chemotherapy agents. It is also approved for the adjuvant treatment of stage III colon cancer following complete resection of the primary tumor. The therapy aims to reduce the risk of cancer recurrence and manage metastatic disease progression.

Side Effects

Common side effects associated with Xalipat 100mg include peripheral sensory neuropathy (numbness or tingling in hands and feet), nausea, vomiting, diarrhea, fatigue, and transient decrease in blood cell counts (myelosuppression). Patients may also experience acute cold-induced sensitivity. Severe adverse effects can include allergic reactions, pulmonary toxicity, or severe neutropenia, requiring immediate medical evaluation.

Precautions & Warnings

Before receiving Xalipat 100mg, patients must inform their healthcare provider of any pre-existing neurological disorders, kidney impairment, or cardiac conditions. Due to its classification as Pregnancy Category D, oxaliplatin can cause fetal harm, making effective contraception essential during and after treatment. Regular monitoring of complete blood counts and neurological function is highly recommended during therapy.

Avoid Interactions

Oxaliplatin is primarily cleared by the kidneys, so co-administration with other nephrotoxic drugs (such as aminoglycosides or loop diuretics) may increase the risk of toxicity. While it does not significantly interact with cytochrome P450 enzymes, combining it with other myelosuppressive agents or neurotoxic drugs can compound adverse effects. Always consult a healthcare professional regarding potential interactions with concurrent medications.

Frequently Asked Questions

Xalipat 100mg is primarily used to treat advanced colorectal cancer and as an adjuvant treatment for stage III colon cancer after the primary tumor has been surgically removed.

Xalipat 100mg is administered as an intravenous (IV) infusion by qualified healthcare professionals in a clinical or hospital setting.

The most common side effects include peripheral neuropathy (numbness or tingling, often triggered by cold), nausea, vomiting, diarrhea, fatigue, and temporary reduction in blood cell counts.

No, Xalipat 100mg is classified under Pregnancy Category D and can cause fetal harm. Effective contraception is required for both male and female patients during treatment.

Patients should avoid exposure to cold drinks and cold temperatures to minimize acute neuropathy, and undergo regular blood tests to monitor kidney function and blood cell counts.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 17 Jun 2026

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