Xerese (Acyclovir + Hydrocortisone Cream) 5% + 1% X 5g

Xerese cream combines acyclovir and hydrocortisone to treat cold sores and related skin irritation. This antiviral and anti-inflammatory combination helps reduce healing time and discomfort. Suitable for external use only. Always follow package directions.

Strength

5% + 1% X 5g

Pack Size

Storage

15-25°

Manufacturer / TM Owner

Bausch Health Companies Inc.

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Indications & Clinical Uses

Xerese cream is used to treat cold sores (herpes labialis) and the associated inflammation. It combines an antiviral agent to combat the virus and a corticosteroid to reduce swelling and itching. This combination therapy may help speed healing and relieve symptoms like pain or tingling.

Side Effects

Many users notice reduced redness and swelling around cold sores within a few days of starting Xerese. The cream may help shorten the duration of outbreaks and ease discomfort. Some people experience mild skin dryness or irritation at the application site.

Precautions & Warnings

Avoid applying Xerese to open wounds, eyes, or mucous membranes. Do not use on skin that is not intact or infected with other conditions. Keep the tube tightly closed and store at room temperature. Wash hands before and after applying to prevent spreading the virus.

Avoid Interactions

No significant drug interactions are reported with Xerese cream. However, avoid combining it with other topical corticosteroids unless directed by a healthcare provider. Using multiple skin products at the same time may increase irritation or reduce effectiveness.

References

Frequently Asked Questions

Xerese is used to treat cold sores caused by the herpes simplex virus and reduce associated skin inflammation.

Apply a thin layer to the affected area five times daily for five days, starting at the first sign of a cold sore.

Consult a healthcare provider before using Xerese if you are pregnant, planning pregnancy, or breastfeeding.

Xerese treats active outbreaks but does not prevent future cold sores from occurring.

Discontinue use and consult a healthcare provider if redness, itching, or swelling worsens after application.

Published by GNH India Pharmaceuticals Limited

Last updated: 17 Jun 2026

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