Product image of Otriven Gegen Schnupfen Einzeldosispipetten Für Erwachsene Und Kinder Ab 12 Jahren (Xylometazoline Hydrochloride) supplied by GNH India

Otriven Gegen Schnupfen Einzeldosispipetten Für Erwachsene Und Kinder Ab 12 Jahren

Active Ingredient:
Xylometazoline Hydrochloride
Origin:
EU

Otriven Gegen Schnupfen Einzeldosispipetten Für Erwachsene Und Kinder Ab 12 Jahren (Xylometazoline Hydrochloride)

Xylometazoline Hydrochloride, the active ingredient in Otriven Gegen Schnupfen Einzeldosispipetten Für Erwachsene Und Kinder Ab 12 Jahren, is an alpha‑adrenergic agonist presented as a nasal spray for topical intranasal use. It relieves nasal congestion associated with colds, sinusitis and allergic rhinitis in adults and children twelve years and older.

GNH India supplies Otriven Gegen Schnupfen Einzeldosispipetten Für Erwachsene Und Kinder Ab 12 Jahren as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Haleon Germany Gmbh

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Indications & Clinical Uses

Xylometazoline nasal spray acts on the nasal vasculature to reduce congestion in several upper‑respiratory conditions.

  • Common cold: provides temporary relief of nasal blockage.
  • Acute sinusitis: eases nasal passage swelling to improve airflow.
  • Allergic rhinitis: diminishes nasal congestion caused by allergen exposure.
  • Seasonal hay fever: reduces congestion during pollen seasons.
  • Non‑infectious rhinitis: alleviates blockage from irritant triggers.

How It Works

  • Xylometazoline hydrochloride selectively stimulates alpha‑2 adrenergic receptors on the smooth muscle of nasal blood vessels, causing vasoconstriction. This reduces blood flow to the nasal mucosa, decreasing edema and opening the nasal passages for improved airflow.

Side Effects

Xylometazoline nasal spray may cause local and systemic reactions, most of which are mild and reversible.

Common Side Effects

  • Nasal burning or stinging sensation.
  • Mild nasal dryness.
  • Sneezing shortly after application.
  • Transient headache.
  • Minor epistaxis (nosebleed).
  • Throat irritation.

Serious or Rare Side Effects

  • Persistent nasal irritation or ulceration.
  • Severe hypertension or elevated blood pressure.
  • Allergic reaction with rash, itching or swelling.
  • Significant nosebleeds requiring medical attention.
  • Vision changes or ocular discomfort.
  • Rebound congestion after prolonged use.

Precautions & Warnings

Before using Xylometazoline nasal spray, consider the following safety measures:

  • Contraindication: avoid if known hypersensitivity to xylometazoline or any formulation component.
  • Age restriction: not recommended for children under 12 years.
  • Duration limit: limit usage to no more than 7 days to prevent rebound congestion.
  • Cardiovascular caution: use with care in patients with hypertension or heart disease.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Xylometazoline may interact with other medications that affect blood pressure or cause vasoconstriction.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs) combined with sympathomimetic decongestants.
  • Systemic alpha‑adrenergic agonists (e.g., phenylephrine) used concurrently.

Moderate Interactions (Monitor Closely)

  • Antihypertensive drugs (beta‑blockers, ACE inhibitors) – monitor blood pressure.
  • Tricyclic antidepressants – observe for additive cardiovascular effects.
  • Nasal corticosteroids – assess for increased local irritation.
  • Herbal supplements containing ephedrine or pseudoephedrine – watch for excess vasoconstriction.

Frequently Asked Questions

Otriven Gegen Schnupfen Einzeldosispipetten contains xylometazoline hydrochloride and is intended to provide temporary relief of nasal congestion caused by colds, sinusitis, allergic rhinitis and other upper‑respiratory irritants in adults and children twelve years of age and older.

Xylometazoline acts as an alpha‑2 adrenergic agonist on the smooth muscle of nasal blood vessels. Stimulation of these receptors causes vasoconstriction, which reduces swelling of the nasal mucosa and opens the airway for easier breathing.

The prescribed dose is determined by a healthcare professional based on the patient’s age, severity of congestion and clinical response. Typically, one or two sprays per nostril every 8‑12 hours is advised, but the exact regimen should follow the prescriber’s instructions.

Safety data for xylometazoline in pregnancy and lactation are limited. It should only be used if the potential benefit outweighs any possible risk, and after consultation with a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Xylometazoline provides rapid, topical vasoconstriction similar to other alpha‑adrenergic decongestants such as oxymetazoline. Compared with systemic decongestants, it has a lower risk of systemic side effects but shares the same limitation of potential rebound congestion if used beyond the recommended duration.

Store the spray at room temperature, preferably below 25 °C, in its original container. Keep it away from moisture, excessive heat and direct sunlight to maintain product stability.

The product is supplied as a single‑dose pipette for intranasal use. The user gently inserts the tip into a nostril, depresses the pipette to deliver the measured spray, and repeats in the other nostril if required, following the prescriber’s guidance.

Serious adverse events, though rare, include persistent nasal irritation or ulceration, significant nosebleeds, severe hypertension, allergic reactions and rebound congestion after prolonged use. Any such symptoms warrant immediate medical evaluation.

Individuals with known hypersensitivity to xylometazoline or any excipients, children under 12 years of age, and patients with uncontrolled hypertension or severe cardiovascular disease should avoid using this product unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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