Otriven Gegen Schnupfen Für Erwachsene Und Kinder Ab 12 Jahren (Xylometazoline Hydrochloride)

Xylometazoline nasal spray acts on the nasal mucosa to reduce congestion in several upper‑respiratory conditions.

• Common cold: provides rapid relief of nasal blockage.
• Acute sinusitis: eases nasal passage obstruction.
• Allergic rhinitis: diminishes swelling and congestion caused by allergens.
• Seasonal hay fever: helps control nasal stuffiness during pollen exposure.

• Xylometazoline hydrochloride selectively stimulates alpha‑adrenergic receptors on the smooth muscle of nasal blood vessels, causing vasoconstriction. This reduces blood flow to the nasal mucosa, decreasing edema and mucus production, which opens the nasal airway and improves airflow.

Adverse reactions are generally mild and related to local irritation of the nasal mucosa.

Common Side Effects

• Burning sensation in the nose: mild discomfort at the application site.
• Nasal dryness: reduced moisture leading to crust formation.
• Sneezing: transient reflex after spray.
• Headache: mild tension-type headache.
• Epistaxis: occasional minor nosebleeds.
• Taste disturbance: temporary alteration of taste perception.

Serious or Rare Side Effects

• Rebound congestion: worsening nasal blockage after prolonged use.
• Severe allergic reaction: rash, itching, swelling, or difficulty breathing.
• Persistent nasal ulceration: ulcer formation with continued irritation.
• Hypertension exacerbation: increased blood pressure in susceptible individuals.

Before using Xylometazoline nasal spray, consider the following safety measures:

• Age restriction: not for children under 12 years.
• Duration limit: limit use to three days to avoid rebound congestion.
• Pre‑existing conditions: avoid if you have severe hypertension or coronary artery disease.
• Pregnancy and lactation: consult a healthcare professional before use.
• Drug interactions: discuss all concurrent nasal or systemic decongestants with your physician.
• Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Xylometazoline may interact with other medications that affect vascular tone or blood pressure.

Major Interactions (Avoid)

• Monoamine oxidase inhibitors (MAOIs): may potentiate hypertensive effects.
• Systemic sympathomimetics: combined use can increase blood pressure.

Moderate Interactions (Monitor Closely)

• Antihypertensive agents: may require blood pressure monitoring.
• Other nasal decongestants: risk of additive local irritation and rebound congestion.
• Tricyclic antidepressants: potential for modest blood pressure elevation.
• Herbal preparations containing ephedra: may enhance sympathomimetic activity.