Otrivine Junior Sine Conservans Décongestionnant (Xylometazoline Hydrochloride)

Otrivine Junior Sine Conservans Décongestionnant is an alpha‑adrenergic nasal decongestant that reduces swelling of the nasal mucosa.

• Common cold: alleviates nasal blockage and improves breathing.
• Allergic rhinitis: decreases nasal swelling caused by allergens.
• Sinusitis: reduces congestion and facilitates sinus drainage.
• Upper respiratory infection: eases nasal passage obstruction.
• Seasonal allergy symptoms: helps clear a blocked nose during pollen exposure.

• Xylometazoline hydrochloride acts as a selective alpha‑adrenergic receptor agonist on the smooth muscle of nasal blood vessels. Stimulation of these receptors causes vasoconstriction, which reduces blood flow to the nasal mucosa, decreasing swelling and opening the nasal passages for improved airflow.

Side effects are generally mild and related to the local action of the spray.

Common Side Effects

• Nasal irritation or burning sensation.
• Mild headache.
• Sneezing shortly after application.
• Dryness of the nasal mucosa.
• Bitter taste in the throat.
• Transient epistaxis (nosebleed).

Serious or Rare Side Effects

• Persistent nasal congestion (rebound congestion) after prolonged use.
• Severe allergic reaction with swelling of the face, lips or throat.
• Significant nosebleeds that do not stop with pressure.
• Hypertensive crisis in susceptible patients.\n

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