Product image of Zefylti (Filgrastim) supplied by GNH India

Zefylti

Active Ingredient:
Filgrastim
Origin:
EU

Zefylti (Filgrastim)

Zefylti (Filgrastim) is a biologic medication used to stimulate white blood cell production. It supports immune function during chemotherapy or bone marrow transplant recovery. This EU-manufactured injectable helps reduce infection risk in patients with low white blood cell counts. A trusted choice for neutropenia management in clinical settings.

Manufacturer / TM Owner

Curateq Biologics S.R.O.

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Indications & Clinical Uses

  • Filgrastim, the active ingredient in Zefylti, is commonly prescribed to boost neutrophil production in patients undergoing chemotherapy or stem cell transplantation. It is also used for individuals with severe chronic neutropenia to maintain healthy white blood cell levels. The medication helps reduce the risk of infections by supporting the body’s immune response during periods of low blood cell counts. Patients with HIV-related neutropenia may also benefit from its immune-supporting effects.

Side Effects

  • Zefylti works by stimulating the bone marrow to produce more white blood cells, particularly neutrophils, which are crucial for fighting infections. Users may notice improved energy levels and reduced susceptibility to illness as their white blood cell counts rise. Some individuals report mild injection-site reactions, such as redness or swelling, which are typically temporary. Regular monitoring helps ensure the medication is effectively supporting immune function.

Precautions & Warnings

  • Zefylti should be handled with care, as it is administered via injection. Patients with a history of allergic reactions to filgrastim or similar biologics should avoid using this medication. Keep the product refrigerated and protect it from light until ready for use. Always follow healthcare provider instructions for proper storage and disposal of used needles. Report any signs of severe pain, swelling, or infection at the injection site immediately.

Avoid Interactions

  • Zefylti may interact with other medications that affect bone marrow function, such as chemotherapy drugs, increasing the risk of excessive white blood cell production. Lithium can enhance the effects of filgrastim, potentially leading to elevated neutrophil counts. Patients should inform their healthcare provider about all medications, including over-the-counter and herbal supplements, before starting Zefylti. Avoid alcohol during treatment, as it may interfere with immune response.

Frequently Asked Questions

Zefylti is used to stimulate white blood cell production, particularly neutrophils, in patients undergoing chemotherapy or with conditions like severe chronic neutropenia.

Zefylti is given as an injection, either under the skin (subcutaneous) or into a vein (intravenous), as directed by a healthcare provider.

Common effects include mild pain or redness at the injection site, bone pain, and temporary flu-like symptoms.

The safety of Zefylti during pregnancy has not been established; consult a healthcare provider before use.

Store Zefylti in the refrigerator, protected from light, and do not freeze. Follow disposal guidelines for used needles.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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