Product image of Zemplar (Paricalcitol) supplied by GNH India

Zemplar

Active Ingredient:
Paricalcitol
Origin:
EU

Zemplar (Paricalcitol)

Paricalcitol (Zemplar) is an intravenous vitamin D analog used to manage secondary hyperparathyroidism in chronic kidney disease. This prescription medication helps regulate calcium and phosphate levels. Suitable for patients on dialysis or with stage 3-5 CKD. Always consult a healthcare provider before use.

Manufacturer / TM Owner

Abbvie S.R.O. (Slovakia)

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Indications & Clinical Uses

  • Paricalcitol is primarily used to treat secondary hyperparathyroidism in adults with chronic kidney disease. It works by reducing elevated parathyroid hormone levels, which can otherwise weaken bones and cause calcium imbalances. The medication is often prescribed when phosphate binders alone are insufficient. It may also be used in patients preparing for kidney transplant.

Side Effects

  • Paricalcitol helps restore balance to calcium and phosphate levels in the body. Patients may notice improved bone health and reduced symptoms like muscle weakness or bone pain. Some individuals experience mild gastrointestinal effects such as nausea or constipation during treatment.

Precautions & Warnings

  • Paricalcitol should be administered under medical supervision, typically in a clinical setting. Blood calcium levels must be monitored regularly to avoid hypercalcemia. Patients with a history of calcium disorders should discuss risks with their doctor. Keep this medication stored at controlled room temperature away from moisture.

Avoid Interactions

  • Paricalcitol may interact with medications that affect calcium metabolism, such as thiazide diuretics or calcium supplements. Strong CYP3A inhibitors can increase paricalcitol levels, requiring dose adjustments. Patients should inform their healthcare provider about all prescription, over-the-counter, and herbal products they use. Avoid alcohol during treatment unless approved by a doctor.

Frequently Asked Questions

Paricalcitol is used to treat secondary hyperparathyroidism in adults with chronic kidney disease, particularly those on dialysis.

Paricalcitol is given as an intravenous injection, usually in a healthcare setting like a clinic or dialysis center.

Common side effects may include nausea, vomiting, or mild gastrointestinal discomfort. Some patients report headache or dizziness.

Paricalcitol may interact with certain drugs, so patients should inform their doctor about all medications they are taking before starting treatment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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