Product image of Zemplar (Paricalcitol) supplied by GNH India

Zemplar

Active Ingredient:
Paricalcitol
Origin:
EU

Zemplar (Paricalcitol)

Paricalcitol (Zemplar) is a vitamin D analog prescribed to manage secondary hyperparathyroidism in chronic kidney disease. This oral medication helps regulate calcium and phosphorus levels. It is suitable for patients on dialysis or with early-stage kidney issues. Always follow healthcare provider guidance when using paricalcitol.

Manufacturer / TM Owner

Abbvie, Lda.

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Indications & Clinical Uses

  • Paricalcitol is primarily used to treat secondary hyperparathyroidism in adults with chronic kidney disease. It helps reduce elevated parathyroid hormone levels, which can impact bone health. The medication is often prescribed when phosphate binders and diet adjustments are insufficient. It may also be used in patients not yet on dialysis to manage early-stage kidney-related parathyroid issues.

Side Effects

  • Paricalcitol works by mimicking the action of vitamin D, helping the body absorb calcium and reduce parathyroid hormone production. Patients may notice improved energy levels or reduced bone discomfort over time. Some individuals report mild gastrointestinal effects like nausea or constipation during the initial weeks of treatment.

Precautions & Warnings

  • Store paricalcitol at room temperature away from moisture and heat. Keep this medication out of reach of children and pets. Inform your healthcare provider about any current medications or supplements before starting paricalcitol. Regular blood tests may be required to monitor calcium, phosphorus, and parathyroid hormone levels.

Avoid Interactions

  • Paricalcitol may interact with other vitamin D supplements, calcium-based medications, or phosphate binders. Certain anticonvulsants, steroids, or cholesterol-lowering drugs can affect how paricalcitol works. Avoid taking magnesium-containing antacids or laxatives without medical advice. Alcohol and grapefruit products may also influence its effectiveness.

Frequently Asked Questions

Paricalcitol is used to treat secondary hyperparathyroidism in adults with chronic kidney disease, helping regulate parathyroid hormone levels.

Paricalcitol is taken orally, usually once daily or as directed by a healthcare provider. Follow the prescribed dose and timing closely.

Some patients may experience mild side effects like nausea, constipation, or dizziness. Report persistent effects to a healthcare professional.

Consult a healthcare provider before using paricalcitol if pregnant or breastfeeding, as effects on unborn children are not fully established.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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