Zovorin - 50mg-ZU (Leucovorin Calcium Vials) 50mg/5ml

Zovorin - 50mg-ZU (Leucovorin Calcium) is a folate derivative used to reduce toxic effects of certain chemotherapy drugs. This 50mg/5ml injectable vial supports cancer treatment protocols. Store at ambient temperature for stability. Ideal for clinical settings requiring folinic acid rescue.

Strength

50mg/5ml

Pack Size

Storage

Ambient

Manufacturer / TM Owner

Zuvius Life Sciences Pvt Ltd

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Pack/s

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Indications & Clinical Uses

Leucovorin Calcium is primarily used to counteract the toxic effects of methotrexate in high-dose chemotherapy. It also enhances the effects of fluorouracil in colorectal cancer treatment. Sometimes prescribed to treat folate deficiency or megaloblastic anemia caused by certain medications. This medication is often part of combination therapy in oncology.

Side Effects

Leucovorin Calcium helps restore normal folate levels in the body, supporting healthy cell function during chemotherapy. It may reduce side effects like nausea or mouth sores associated with methotrexate toxicity. Patients often report improved energy levels as folate stores are replenished. The medication works by bypassing blocked metabolic pathways.

Precautions & Warnings

Keep this medication away from children and pets in a secure location. Store at room temperature, avoiding direct sunlight or moisture. Always check the vial for particles or discoloration before use. Discard any unused portion properly after opening. Consult a healthcare provider if pregnant or breastfeeding.

Avoid Interactions

Leucovorin Calcium may interact with certain antibiotics like trimethoprim or pyrimethamine. Combining with phenytoin or fosphenytoin can reduce seizure medication effectiveness. Alcohol may diminish its benefits during chemotherapy. Always inform your doctor about all medications, including over-the-counter products.

References

Frequently Asked Questions

It is used to reduce toxic effects of methotrexate chemotherapy and enhance fluorouracil treatment in colorectal cancer.

Store at ambient temperature, away from moisture and direct light. Keep out of reach of children.

Consult a healthcare provider before use if pregnant or breastfeeding.

Possible effects include nausea, fatigue, or allergic reactions. Report severe symptoms to a doctor.

Published by GNH India Pharmaceuticals Limited

Last updated: 17 Jun 2026

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