Product image of ADVIL COLD AND SINUS 200 mg/1 (Ibuprofen and Pseudoephedrine Hydrochloride) 200 mg/1 TABLET, COATED supplied by GNH India

ADVIL COLD AND SINUS 200 mg/1

Active Ingredient:
Ibuprofen and Pseudoephedrine Hydrochloride
Form:
TABLET, COATED
Brand:
ADVIL COLD AND SINUS
Origin:
USA

ADVIL COLD AND SINUS 200 mg/1 (Ibuprofen and Pseudoephedrine Hydrochloride TABLET, COATED) 200 mg/1

Ibuprofen and Pseudoephedrine Hydrochloride, the active ingredients in Advil Cold and Sinus, is a combination of a nonsteroidal anti-inflammatory drug (NSAID) and a sympathomimetic decongestant presented as a 200 mg/1 mg coated tablet for oral use. It is used to relieve nasal congestion, sinus pressure, minor aches and pains, and fever associated with the common cold, flu, or allergies. GNH India supplies Advil Cold and Sinus as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

GNH India supplies Advil Cold and Sinus as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Strength

200 mg/1

Pack Size

2 CARTON in 1 PACKAGE (0573-2160-74) / 4 BLISTER PACK in 1 CARTON / 10 TABLET, COATED in 1 BLISTER

Manufacturer / TM Owner

Haleon US Holdings LLC

1
Pack/s
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Indications & Clinical Uses

Advil Cold and Sinus is used to treat symptoms associated with the common cold, flu, and allergies. It acts on the respiratory and inflammatory pathways to provide relief.

  • Common Cold: Relieves nasal congestion, sinus pressure, and minor aches and pains associated with the common cold.
  • Sinus Congestion: Reduces sinus pressure and congestion.
  • Fever: Helps to reduce fever associated with cold and flu.
  • Allergic Rhinitis: Alleviates symptoms of allergic rhinitis, including nasal congestion and sinus pressure.

How It Works

  • Ibuprofen inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis and thereby providing analgesic, antipyretic, and anti-inflammatory effects. Pseudoephedrine hydrochloride acts as an alpha-adrenergic agonist, causing vasoconstriction of nasal mucosal blood vessels and reducing nasal congestion.

Side Effects

Advil Cold and Sinus may cause various side effects, ranging from common to serious or rare.

Common Side Effects

  • Nausea
  • Dizziness
  • Headache
  • Dry mouth
  • Insomnia
  • Increased heart rate
  • Nervousness
  • Increased blood pressure

Serious or Rare Side Effects

  • Severe allergic reactions
  • Gastrointestinal bleeding
  • Ulcers
  • Liver toxicity
  • Kidney problems
  • Heart problems
  • Seizures

Precautions & Warnings

Advil Cold and Sinus should be used with caution and under the guidance of a healthcare professional. Important precautions include:

  • Avoid use if allergic to ibuprofen or pseudoephedrine: Do not use if you have a known allergy to these ingredients.
  • Consult a doctor before use if pregnant or breastfeeding: Use during pregnancy or breastfeeding should be discussed with a healthcare provider.
  • Avoid use with certain medical conditions: Consult a doctor if you have high blood pressure, heart disease, or liver/kidney disease.
  • Avoid use with other medications: Consult a doctor before using with other medications, especially blood thinners and other NSAIDs.
  • Avoid use with alcohol: Alcohol can increase the risk of side effects.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Advil Cold and Sinus may interact with other medications, leading to potential complications. Important interactions include:

Major Interactions (Avoid)

  • Blood thinners (e.g., warfarin): Increased risk of bleeding.
  • Other NSAIDs (e.g., aspirin): Increased risk of gastrointestinal bleeding.
  • MAO inhibitors: Increased risk of hypertensive crisis.
  • Beta-blockers: Reduced effectiveness of beta-blockers.
  • Digoxin: Increased risk of digoxin toxicity.

Moderate Interactions (Monitor Closely)

  • Diuretics: Reduced effectiveness of diuretics.
  • Lithium: Increased risk of lithium toxicity.
  • Methotrexate: Increased risk of methotrexate toxicity.
  • Corticosteroids: Increased risk of gastrointestinal bleeding.

Frequently Asked Questions

Advil Cold and Sinus is used to relieve nasal congestion, sinus pressure, minor aches and pains, and fever associated with the common cold, flu, or allergies. It combines the NSAID ibuprofen for pain and fever relief with the decongestant pseudoephedrine to reduce nasal and sinus congestion.

Ibuprofen inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis and thereby providing analgesic, antipyretic, and anti-inflammatory effects. Pseudoephedrine hydrochloride acts as an alpha-adrenergic agonist, causing vasoconstriction of nasal mucosal blood vessels and reducing nasal congestion.

The usual dose of Advil Cold and Sinus should be determined by a healthcare professional based on the patient's condition and medical history. Always follow the prescribed dosage and consult your doctor or pharmacist for specific instructions.

Use of Advil Cold and Sinus during pregnancy or breastfeeding should be discussed with a healthcare provider. Ibuprofen is generally not recommended during the third trimester of pregnancy, and pseudoephedrine should be used with caution. Always consult your doctor before use.

To order Advil Cold and Sinus from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.

Advil Cold and Sinus combines ibuprofen for pain and fever relief with pseudoephedrine for nasal and sinus congestion. Unlike some other decongestants that may cause drowsiness, pseudoephedrine is non-drowsy. However, it may not be suitable for everyone, especially those with certain medical conditions or those taking specific medications.

Advil Cold and Sinus should be stored below 25°C, kept in the original pack, and protected from moisture. Ensure the packaging is intact and the product is used before the expiration date. Always follow the storage instructions provided on the packaging.

Advil Cold and Sinus is administered orally in the form of coated tablets. The tablets should be swallowed whole with a glass of water, and the dosage should be as prescribed by a healthcare professional. Do not crush or chew the tablets unless instructed to do so.

The most serious risks to watch for with Advil Cold and Sinus include severe allergic reactions, gastrointestinal bleeding, ulcers, liver toxicity, kidney problems, heart problems, and seizures. If you experience any severe side effects, seek medical attention immediately.

Advil Cold and Sinus should not be used by individuals who are allergic to ibuprofen or pseudoephedrine, those with severe high blood pressure, heart disease, or liver/kidney disease, and those taking certain medications such as blood thinners and other NSAIDs. Always consult your doctor before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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